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San Martín, Álvaro ; Rodriguez-Aliaga, Piere ; Molina, José Alejandro ; Martin, Andreas ; Bustamante, Carlos ; Báez, Mauricio | National Academy of Sciences | 2019-01-25T15:28:04ZATP-dependent proteases translocate proteins through a narrow pore for their controlled destruction. However, how a protein substrate containing a knotted topology affects this process remains unknown. Here, we characterized the effects of the t[...]texto impreso
Doniselli, Nicola ; Rodriguez-Aliaga, Piere ; Amidani, Davide ; Bardales, Jorge A. ; Bustamante, Carlos ; Guerra, Daniel G. ; Rivetti, Claudio | Oxford University Press | 2019-02-06T14:53:08ZThe stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind RNA polymerase (RNAP) and regulate gene expression to adapt bacteria to different environmental conditions. Here, we use Atomic Force Microscopy and in vi[...]
