| Título: | Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. |
| Autores: | Phan, Tung Gia ; Del Valle Mendoza, Juana Mercedes ; Sadeghi, Mohammadreza ; Altan, Eda ; Deng, Xutao ; Delwart, Eric |
| Tipo de documento: | texto impreso |
| Editorial: | Springer International Publishing, 2017-10-27T19:53:47Z |
| Dimensiones: | application/pdf |
| Nota general: |
Archived with thanks to Virus genes info:eu-repo/semantics/openAccess |
| Idiomas: | Inglés |
| Palabras clave: | Facultad de Ciencias de la Salud , Pregrado , Artículos científicos , Medicina |
| Resumen: |
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown. Revisión por pares |
| En línea: | Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Genes |
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