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St Jean, P.L. ; Koh, G.C.K.W. ; Breton, J.J. ; Espino, F.E.J. ; Hien, T.T. ; Krudsood, S. ; Lacerda, M.V.G. ; Llanos-Cuentas, A. ; Lon, C. ; Mohammed, R. ; Namaik-Larp, C.S. ; Pereira, D.B. ; Saunders, D.L. ; Velez, I.D. ; Yilma, D. ; Villegas, M.F. ; Duparc, S. ; Green, J.A. | Lippincott Williams and Wilkins | 2020-12-14T16:10:15ZPlasmodium vivax has the largest geographic range of human malaria species and is challenging to manage and eradicate due to its ability to establish a dormant liver stage, the hypnozoite, which can reactivate leading to relapse. Until recently,[...]texto impreso
Llanos-Cuentas, A. ; Lacerda, M.V.G. ; Hien, T.T. ; Velez, I.D. ; Namaik-Larp, C. ; Chu, C.S. ; Villegas, M.F. ; Val, F. ; Monteiro, W.M. ; Brito, M.A.M. ; Costa, M.R.F. ; Chuquiyauri, R. ; Casapía, M. ; Nguyen, C.H. ; Aruachan, S. ; Papwijitsil, R. ; Nosten, F.H. ; Bancone, G. ; Angus, B. ; Duparc, S. ; Craig, G. ; Rousell, V.M. ; Jones, S.W. ; Hardaker, E. ; Clover, D.D. ; Kendall, L. ; Mohamed, K. ; Koh, G.C.K.W. ; Wilches, V.M. ; Breton, J.J. ; Green, J.A. | Massachusetts Medical Society | 2019-12-06T20:57:47ZBACKGROUND Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed “radical cure.” METHODS We performed a phase 3, prospec[...]
