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Rodrigues-Soares, Fernanda ; Penas-Lledo, Eva M. ; Tarazona-Santos, Eduardo ; Sosa-Macias, Martha ; Teran, Enrique ; Lopez-Lopez, Marisol ; Rodeiro, Idania ; Moya, Graciela E. ; Calzadilla, Luis R. ; Ramirez-Roa, Ronald ; Grazina, Manuela ; Estevez-Carrizo, Francisco E. ; Barrantes, Ramiro ; Llerena, Adrian | American Society for Clinical Pharmacology and Therapeutics | 2019-08-08T15:23:45ZWe present the distribution of CYP2D6, CYP2C9 and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero-America (n> 6,000) in the context of genetic ancestry (n=3,387). Continental ancestries are the major de[...]texto impreso
Chacon-Duque, Juan-Camilo ; Adhikari, Kaustubh ; Fuentes-Guajardo, Macarena ; Mendoza-Revilla, Javier ; Acuna-Alonzo, Victor ; Barquera, Rodrigo ; Quinto-Sanchez, Mirsha ; Gomez-Valdes, Jorge ; Everardo Martínez, Paola ; Villamil-Ramirez, Hugo ; Hunemeier, Tabita ; Ramallo, Virginia ; Silva de Cerqueira, Caio C. ; Hurtado, Malena ; Villegas, Valeria ; Granja, Vanessa ; Villena, Mercedes ; Vásquez, Rene ; Llop, Elena ; Sandoval, Jose R. ; Salazar-Granara, Alberto A. ; Parolin, Maria-Laura ; Sandoval, Karla ; Peñaloza-Espinosa, Rosenda I. ; Rangel-Villalobos, Héctor ; Winkler, Cheryl A. ; Klitz, William ; Bravi, Claudio ; Molina, Julio ; Corach, Daniel ; Barrantes, Ramiro ; Gomes, Veronica ; Resende, Carlos ; Gusmão, Leonor ; Amorim, Antonio ; Xue, Yali ; Dugoujon, Jean-Michel ; Moral, Pedro ; González-José, Rolando ; Schuler-Faccini, Lavinia ; Salzano, Francisco M. ; Bortolini, Maria-Cátira ; Canizales-Quinteros, Samuel ; Poletti, Giovanni ; Gallo, Carla ; Bedoya, Gabriel ; Rothhammer, Francisco ; Balding, David ; Hellenthal, Garrett ; Ruiz-Linares, Andrés | Nature Research | 2019-03-05T15:23:28ZHistorical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-cont[...]
