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Adaui, Vanessa ; Lye, Lon-Fye ; Akopyants, Natalia S. ; Zimic, Mirko ; Llanos-Cuentas, Alejandro ; Garcia, Lineth ; Maes, Ilse ; De Doncker, Simonne ; Dobson, Deborah E. ; Arevalo, Jorge ; Dujardin, Jean-Claude ; Beverley, Stephen M. | Oxford University Press | 2019-02-06T14:57:40ZCutaneous and mucosal leishmaniasis, caused in South America by Leishmania braziliensis, is difficult to cure by chemotherapy (primarily pentavalent antimonials [Sb(V)]). Treatment failure does not correlate well with resistance in vitro, and th[...]texto impreso
Jara, Marlene ; Berg, Maya ; Caljon, Guy ; de Muylder, Geraldine ; Cuypers, Bart ; Castillo, Denis ; Maes, Ilse ; Orozco, María Del Carmen ; Vanaerschot, Manu ; Dujardin, Jean-Claude ; Arevalo, Jorge | Public Library of Science | 2019-01-25T15:28:05ZIt was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana and Leishmania (Leishm[...]
