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Bouton, Tara C. ; Phillips, Patrick P. J. ; Mitnick, Carole D. ; Peloquin, Charles A. ; Eisenach, Kathleen ; Patientia, Ramonde F. ; Lecca, Leonid ; Gotuzzo, Eduardo ; Gandhi, Neel R. ; Butler, Donna ; Diacon, Andreas H. ; Martel, Bruno ; Santillan, Juan ; Hunt, Kathleen Robergeau ; Vargas, Dante ; von Groote-Bidlingmaier, Florian ; Seas, Carlos ; Dianis, Nancy ; Moreno-Martinez, Antonio ; Horsburgh, C. Robert | BMC | 2019-01-25T16:59:36ZBACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroqu[...]texto impreso
Peloquin, Charles A. ; Phillips, Patrick P. J. ; Mitnick, Carole D. ; Eisenach, Kathleen ; Patientia, Ramonde F. ; Lecca, Leonid ; Gotuzzo, Eduardo ; Gandhi, Neel R. ; Butler, Donna ; Diacon, Andreas H. ; Martel, Bruno ; Santillan, Juan ; Hunt, Kathleen Robergeau ; Vargas, Dante ; von Groote-Bidlingmaier, Florian ; Seas, Carlos ; Dianis, Nancy ; Moreno-Martinez, Antonio ; Kaur, Pawandeep ; Horsburgh, C. Robert | American Society of Microbiology | 2018-11-30T17:17:13ZPatients with multidrug-resistant tuberculosis in Peru and South Africa were randomized to a weight-banded nominal dose of 11, 14, 17, or 20 mg/kg/day levofloxacin (minimum, 750 mg) in combination with other second-line agents. A total of 101 pa[...]
