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Florentini, E.A. ; Angulo, N. ; Gilman, R.H. ; Alcántara, R. ; Roncal, E. ; Antiparra, R. ; Toscano, E. ; Vallejos, K. ; Kirwan, D. ; Zimic, M. ; Sheen, P. | Public Library of Science | 2020-12-14T16:06:23ZPyrazinamide (PZA) susceptibility testing in Mycobacterium tuberculosis (Mtb) is a current area of development and PZA-resistant strains are increasingly prevalent. Previous studies have demonstrated that the detection of pyrazinoic acid (POA), [...]texto impreso
Alcántara, R. ; Fuentes, P. ; Antiparra, R. ; Santos, M. ; Gilman, R.H. ; Kirwan, D.E. ; Zimic, M. ; Sheen, P. | American Society for Microbiology | 2019-12-06T21:02:57ZAlthough pyrazinamide (PZA) is a key component of first- and second-line tuberculosis treatment regimens, there is no gold standard to determine PZA resistance. Approximately 50% of multidrug-resistant tuberculosis (MDR-TB) and over 90% of exten[...]
