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Castillo, Denis ; Sauvain, Michel ; Rivaud, Marion ; Jullian, Valerie | Georg Thieme Verlag | 2020-06-10T18:12:14ZSeven benzo[c]phenanthridines, synthetic or isolated from Zanthoxylum rhoifolium root bark, were evaluated against Leishmania amazonensis axenic amastigotes. Five of them were considered leishmanicidal, with IC50 values ranging from 0.03 to 0.5[...]texto impreso
Vasquez-Ocmin, Pedro ; Haddad, Mohamed ; Gadea, Alice ; Jullian, Valerie ; Castillo, Denis ; Paloque, Lucie ; Cerapio, Juan Pablo ; Bourdy, Genevieve ; Sauvain, Michel | Taylor & Francis | 2019-01-25T15:02:14ZOne new phthalide (1) was isolated from aerial parts of Peperomia nivalis, along with known compounds (2 and 3), reported in this species for the first time. The structure of the new compound was characterised on the basis of 1D ((1)H and (13)C [...]texto impreso
Trinel, Manon ; Jullian, Valerie ; Le Lamer, Anne-Cecile ; Mhamdi, Icram ; Mejia, Kember ; Castillo, Denis ; Cabanillas, Billy Joel ; Fabre, Nicolas | Wiley | 2018-11-30T22:50:36ZINTRODUCTION: The phytochemistry of the latex of Hura crepitans L. (Euphorbiaceae), a widespread tree in the Amazonian forest having many uses, is little known. Only huratoxin, a daphnane diterpene orthoester, has been described despite the high[...]
