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CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis

Menezes, S.M. ; Decanine, D. ; Brassat, D. ; Khouri, R. ; Schnitman, S.V. ; Kruschewsky, R. ; López, G. ; Álvarez, C. ; Talledo, M. ; Gotuzzo, E. ; Vandamme, A.-M. ; Galvão-Castro, B. ; Liblau, R. ; Weyenbergh, J.V. | BMC | 2020-06-10T18:12:16Z

Background: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies[...]

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