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Analysis of complement-mediated lysis of simian immunodeficiency virus (SIV) and SIV-infected cells reveals sex differences in vaccine-induced immune responses in rhesus macaques

Miller-Novak, Leia K. ; Das, Jishnu ; Musich, Thomas A. ; Demberg, Thorsten ; Weiner, Joshua A. ; Venzon, David J. ; Mohanram, Venkatramanan ; Vargas-Inchaustegui, Diego A. ; Tuero, Iskra ; Ackerman, Margaret E. ; Alter, Galit ; Robert-Guroff, Marjorie | American Society for Microbiology | 2018-11-30T23:41:31Z

An effective human immunodeficiency virus (HIV) vaccine has yet to be developed, and defining immune correlates of protection against HIV infection is of paramount importance to inform future vaccine design. The complement system is a component [...]

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