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Beltrán Beck, Beatriz ; Romero Martínez, Beatriz ; Sevilla, Iker A ; Barasona, Jose A ; Garrido, Joseba M ; González-Barrio, David ; Díez Delgado, Iratxe ; Minguijón, Esmeralda ; Casal, Carmen ; Vicente, Joaquín ; Gortazar, Christian ; Aranaz Martín, Alicia | American Society for Microbiology | 2014-01Wildlife vaccination is increasingly being considered as an option for tuberculosis control. We combined data from laboratory trials and an ongoing field trial to assess the risk of an oral Mycobacterium bovis BCG vaccine and a prototype heat-in[...]texto impreso
Rodríguez Prieto, Víctor ; Martínez López, Beatriz ; Barasona, José Angel ; Acevedo, Pelayo ; Romero Martínez, Beatriz ; Rodriguez Campos, Sabrina ; Gortazar, Christian ; Sánchez-Vizcaíno, José Manuel ; Vicente, Joaquín | BioMedCentral | 2012-08-30BACKGROUND Bovine tuberculosis (bTB) is a chronic infectious disease mainly caused by Mycobacterium bovis. Although eradication is a priority for the European authorities, bTB remains active or even increasing in many countries, causing signifi[...]texto impreso
De la Fuente, Jose ; Díez Delgado, Iratxe ; Contreras, Marinela ; Vicente, Joaquín ; Cabezas Cruz, Alejandro ; Tobes, Raquel ; Manrique, Marina ; López, Vladimir ; Romero Martínez, Beatriz ; Bezos Garrido, Javier ; Domínguez Rodríguez, Lucas ; Sevilla, Iker A ; Garrido, Joseba M ; Juste, Ramón ; Madico, Guillermo ; Jones-López, Edward ; Gortazar, Christian | Public Library Science | 2015-11Mycobacteria of the Mycobacterium tuberculosis complex (MTBC) greatly affect humans and animals worldwide. The life cycle of mycobacteria is complex and the mechanisms resulting in pathogen infection and survival in host cells are not fully unde[...]texto impreso
De la Fuente, Jose ; Díez Delgado, Iratxe ; Contreras, Marinela ; Vicente, Joaquín ; Cabezas Cruz, Alejandro ; Manrique, Marina ; Tobes, Raquel ; López, Vladimir ; Romero, Beatriz ; Domínguez Rodríguez, Lucas ; Garrido, Joseba M ; Juste, Ramón ; Gortazar, Christian | American Society for Microbiology | 2015-06-25Here we report the complete genome sequences of field isolates of Mycobacterium bovis and the related mycobacterial species, Mycobacterium caprae. The genomes of three M. bovis (MB1, MB3, MB4) and one M. caprae (MB2) field isolates with differen[...]texto impreso
Ruiz Fons, Francisco ; Fernández de Mera, Isabel G ; Acevedo, Pelayo ; Gortazar, Christian ; De la Fuente, Jose | American Society for Microbiology | 2012-04Environmental factors may drive tick ecology and therefore tick-borne pathogen (TBP) epidemiology, which determines the risk to animals and humans of becoming infected by TBPs. For this reason, the aim of this study was to analyze the influence [...]texto impreso
Galindo, Ruth C ; Ayllón, Nieves ; Smrdel, Katja Strašek ; Boadella, Mariana ; Beltrán-Beck, Beatriz ; Mazariegos Martínez-Peñalver, María ; García Benzaquén, Nerea ; de la Lastra, José M Pérez ; Avsic-Zupanc, Tatjana ; Kocan, Katherine M ; Gortazar, Christian ; De la Fuente, Jose | BioMedCentral | 2012-08-30BACKGROUND Anaplasma phagocytophilum infects a wide variety of hosts and causes granulocytic anaplasmosis in humans, horses and dogs and tick-borne fever in ruminants. Infection with A. phagocytophilum results in the modification of host gene e[...]texto impreso
Gamino, Virginia ; Gutiérrez Guzmán, Ana Valeria ; Fernández de Mera, Isabel G ; Ortíz, José Antonio ; Durán Martín, Mauricio ; De la Fuente, Jose ; Gortazar, Christian ; Höfle, Ursula | BioMedCentral | 2012-09-11In late summer 2010 a mosquito born flavivirus not previously reported in Europe called Bagaza virus (BAGV) caused high mortality in red-legged partridges (Alectoris rufa) and ring-necked pheasants (Phasianus colchicus). We studied clinical find[...]texto impreso
Gortazar, Christian ; Beltrán-Beck, Beatriz ; Garrido, Joseba M ; Aranaz Martín, Alicia ; Sevilla, Iker A ; Boadella, Mariana ; Lyashchenko, Konstantin P ; Galindo, Ruth C ; Montoro, Vidal ; Domínguez Rodríguez, Lucas ; Juste, Ramón ; De la Fuente, Jose | BioMedCentral | 2014-04-26BACKGROUND Field vaccination trials with Mycobacterium bovis BCG, an attenuated mutant of M. bovis, are ongoing in Spain, where the Eurasian wild boar (Sus scrofa) is regarded as the main driver of animal tuberculosis (TB). The oral baiting str[...]texto impreso
Beltrán-Beck, Beatriz ; De la Fuente, Jose ; Garrido, Joseba M ; Aranaz Martín, Alicia ; Sevilla, Iker ; Villar, Margarita ; Boadella, Mariana ; Galindo, Ruth C ; Pérez de la Lastra, José M ; Moreno Cid, Juan A ; Fernández de Mera, Isabel G ; Alberdi, Pilar ; Santos, Gracia ; Ballesteros, Cristina ; Lyashchenko, Konstantin P ; Minguijón, Esmeralda ; Romero Martínez, Beatriz ; Juan Ferré, Lucia de ; Domínguez Rodríguez, Lucas ; Juste, Ramón ; Gortazar, Christian | Public Library Science | 2014Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model fo[...]texto impreso
Cabal Rosel, Adriana ; García Castillo, María ; Cantón Moreno, Rafael ; Gortazar, Christian ; Domínguez Rodríguez, Lucas ; Alvarez, Julio | Frontiers Media | 2016Etiological diagnosis of diarrheal diseases may be complicated by their multi-factorial nature. In addition, Escherichia coli strains present in the gut can occasionally harbor VGs without causing disease, which complicates the assessment of the[...]texto impreso
Dieli, Francesco ; Garrido, Joseba M. ; Sevilla, Iker A. ; Beltrán-Beck, Beatriz ; Minguijón, Esmeralda ; Ballesteros, Cristina ; Galindo, Ruth C. ; Boadella, Mariana ; Lyashchenko, Konstantin P. ; Romero Martínez, Beatriz ; Geijo, Maria Victoria ; Ruiz Fons, Francisco ; Aranaz Martín, Alicia ; Juste, Ramón A. ; Vicente, Joaquín ; De la Fuente, Jose ; Gortazar, Christian | 2011Tuberculosis (TB) caused by Mycobacterium bovis and closely related members of the Mycobacterium tuberculosis complex continues to affect humans and animals worldwide and its control requires vaccination of wildlife reservoir species such as Eur[...]texto impreso
Beltrán-Beck, Beatriz ; Romero Martínez, Beatriz ; Boadella, Mariana ; Casal, Carmen ; Bezos Garrido, Javier ; Mazariegos Martínez-Peñalver, María ; Martín, MariPaz ; Galindo, Ruth C ; Pérez de la Lastra, José M ; Villar, Margarita ; Garrido, Joseba M ; Sevilla, Iker A ; Asensio, Fernando ; Sicilia, Javier ; Lyashchenko, Konstantin P ; Domínguez Rodríguez, Lucas ; Juste, Ramón A ; De la Fuente, Jose ; Gortazar, Christian | American Society for Microbiology | 2014-08Mycobacterium bovis causes animal tuberculosis (TB) in cattle, humans, and other mammalian species, including pigs. The goal of this study was to experimentally assess the responses of pigs with and without a history of tonsillectomy to oral vac[...]texto impreso
Acevedo, Pelayo ; Romero Martínez, Beatriz ; Vicente, Joaquín ; Caracappa, Santo ; Galluzzo, Paola ; Marineo, Sandra ; Vicari, Domenico ; Torina, Alessandra ; Casal, Carmen ; De la Fuente, Jose ; Gortazar, Christian | Public Library Science | 2013Because of their relative simplicity and the barriers to gene flow, islands are ideal systems to study the distribution of biodiversity. However, the knowledge that can be extracted from this peculiar ecosystem regarding epidemiology of economic[...]texto impreso
Muñoz Mendoza, Marta ; Marreros, Nelson ; Boadella, Mariana ; Gortazar, Christian ; Menéndez, Santiago ; Juan Ferré, Lucía ; Bezos Garrido, Javier ; Romero Martínez, Beatriz ; Copano, María Francisca ; Amado, Javier ; Saez, Jose Luis ; Mourelo, Jorge ; Balseiro, Ana | BioMedCentral | 2013-09-08BACKGROUND Infections with Mycobacterium bovis and closely related members of the Mycobacterium tuberculosis complex (MTC) are shared between livestock, wildlife and sporadically human beings. Wildlife reservoirs exist worldwide and can interfe[...]
