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Soriano Romaní, Laura ; Vicario de la Torre, Marta ; López García, Antonio ; Crespo Moral, Mario ; Herrero-Vanrell, Rocio ; Molina Martínez, Irene Teresa ; Diebold Luque, Yolanda | Elsevier | 2017-01In ocular surface inflammatory diseases, such as dry eye disease, long-term symptom relief requires targeting the inflammation itself rather than treating only the surface-associated dryness with artificial tears. Therefore, we included an anti-[...]texto impreso
Wojtusik, Mateusz ; Rodríguez Martín, Alberto ; Ripoll Morales, Vanessa ; Santos Mazorra, Victoria E. ; García, Jose L. ; García-Ochoa Soria, Félix | Elsevier | 2015Production of 1,3-propanediol from glycerol using Klebsiella oxytoca NRRL-B199 has been studied. Medium composition has been optimized by means of a statistical design based on the Taguchi method. Strong influences of glycerol and phosphate conc[...]texto impreso
Rodríguez, Alberto ; Wojtusik, Mateusz ; Ripoll, Vanessa ; Santos, Victoria E. ; García-Ochoa, F. | Elsevier | 2015-10-23Shimwellia blattae ATCC 33430 as biocatalyst in the conversion of 1,3-propanediol from glycerol is herein evaluated. Several operational conditions in batch cultivations, employing pure and raw glycerol as sole carbon source, were studied. Tempe[...]texto impreso
Estañ, María Cristina ; Calviño, Eva ; Blas, Elena de ; Boyano Adánez, María del Carmen ; Mena, María Luz ; Gómez Gómez, M.Milagros ; Rial, Eduardo ; Aller, Patricio | Elsevier | 2012While the anti-tumor efficacy of 2-deoxy-D-glucose (2-DG) is normally low in monotherapy, it may represent a valuable radio- and chemo-sensitizing agent. We here demonstrate that 2–10 mM 2-DG cooperates with arsenic trioxide (ATO) and other anti[...]texto impreso
Redondo Useros, Noemí ; Gheorghe, Alina ; Pérez de Heredia, Fátima ; Díaz, Ligia Esperanza ; Baccan, Gyselle Chrystina ; Fuente del Rey, Mónica de la ; Marcosa, Ascensión | Elsevier | 2019-11-29Objective We aimed to assess whether 2-hydroxyoleic acid (2-OHOA) and n-3 polyunsaturated fatty acids (PUFA) could counteract changes on adipokine secretion and cardiometabolic risk biomarkers associated with high-fat diet-induced obesity in mic[...]texto impreso
Alcock, James E ; Martínez Catalán, José R. ; Rubio Pascual, Francisco J. ; Díez Montes, Alejandro ; Díez Fernández, Rubén ; Gómez Barreiro, Juan ; Arenas Martín, Ricardo ; Dias da Silva, Ícaro ; González Clavijo, Emilio | Elsevier | 2015-08-30A model for the P–T–t evolution of NW and Central Iberia is presented to better understand its metamorphic evolution from initial Barrovian stage through HT–LP conditions. The model is constrained by the well-known succession of structural event[...]texto impreso
Ferrater Gómez, Marta ; Echeverria, Anna ; Masana Closa, Eulàlia ; Martínez Díaz, José J. ; Sharp, Warren D | Elsevier | 2016The slip rate of a seismogenic fault is a crucial parameter for establishing the contribution of the fault tothe seismic hazard. It is calculated from measurements of the offset of linear landforms, such channels,produced by the fault combined w[...]texto impreso
Lobate scarps are the topographic expression of the largest thrust faults observed on the surfaces of terrestrial planets and their study provides information on the mechanical characteristics of the lithosphere at the time of formation. Here we[...]texto impreso
Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved with the design of 3D implants, which combine the merits of osseous[...]texto impreso
Vila, Mercedes ; García, Ana ; Girotti, Alessandra ; Alonso, Matilde ; Rodriguez Cabello, José Carlos ; González Vázquez, Arlyng ; Planell, Josep A. ; Engel, Elisabeth ; Buján, Julia ; García-Honduvilla, Natalio ; Vallet Regí, María | Elsevier | 2016The current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. Silicon doped hydroxyap[...]texto impreso
In the northwest Iberian Range the Aalenian to Bajocian interval is represented by condensed, as well as more expanded marine carbonate strata deposited in a shallow epicontinental-sea setting. Precise biochronological data (successive ammonites[...]texto impreso
Dominguez, Carmen M. ; Rodríguez Gutiérrez, Vanesa ; Montero González, Esperanza ; Romero, Arturo ; Santos, Aurora | Elsevier | 2020The alkaline activation of persulfate (PS) has been tested in this study as in situ oxidation technology for the abatement of dichloromethane (DCM), a chlorinated volatile organic pollutant commonly found in groundwater due to its wide use as so[...]texto impreso
Boekstegers, Felix ; Marcelain, Katherine ; Barahona Ponce, Carol ; Baez Benavides, Pablo F. ; Müller, Bettina ; de Toro, Gonzalo ; Retamales, Javier ; Barajas, Olga ; Ahumada, Monica ; Morales, Erik ; Rojas, Armando ; Sanhueza, Verónica ; Loader, Denisse ; Rivera, María Teresa ; Gutiérrez, Lorena ; Bernal, Giuliano ; Ortega, Alejandro ; Montalvo, Domingo ; Portiño, Sergio ; Bertrán, Maria Enriqueta ; Gabler, Fernando ; Spencer, Loreto ; Olloquequi, Jordi ; González Silos, Rosa ; Fischer, Christine ; Scherer, Dominique ; Jenab, Mazda ; Aleksandrova, Krasimira ; Katzke, Verena ; Weiderpass, Elisabete ; Moradi, Tahereh ; Fischer, Krista ; Bossers, Willem ; Brenner, Hermann ; Hveem, Kristian ; Eklund, Niina ; Völker, Uwe ; Waldenberger, Melanie ; Fuentes Guajardo, Macarena ; González-José, Rolando ; Bedoya, Gabriel ; Bortolini, Maria C. ; Canizales, Samuel ; Gallo, Carla ; Ruiz Linares, Andres ; Rothhammer, Francisco ; Lorenzo Bermejo, Justo | Elsevier | 2020-07-14T00:00:57ZBACKGROUND: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. We investigated whether t[...]texto impreso
Some abrasion surfaces displayed by internal moulds of ammonites, such as annular abrasion furrows formed on the venter surface and ellipsoidal abrasion facets preferentially developed on the last third part of the preserved whorl, are diagnosti[...]texto impreso
It is shown that neither the Schrödinger equation nor the Klein-Gordon one with logarithmic nonlinearities have dissipative solutions. In the case of one-dimensional space, numerical experiments with different Cauchy data, in the nonrelativistic[...]
