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Documentos disponibles de esta editorial (2214)
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Khayet Souhaimi, Mohamed ; García Villaluenga, Juan Pedro ; Godino Gómez, María Paz ; Mengual Cabezón, Juan Ignacio ; Seoane Rodríguez, Benjamín ; Khulbe, K. C. ; Matsuura, T. | Elsevier | 2004-10-15Dense flat-sheet membranes were prepared from poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) using the casting solvents chloroform and 1,1,2-trichloroethylene. X-ray diffraction, tapping mode atomic force microscopy (TM-AFM), and contact angle stu[...]![]()
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Ford, James D. ; Sherman, Mya ; Berrang-Ford, Lea ; Llanos, Alejandro ; Carcamo, Cesar ; Harper, Sherilee ; Lwasa, Shuaib ; Namanya, Didacus ; Marcello, Thomas ; Maillet, Michelle ; Edge, Victoria | Elsevier | 2018-12-01T00:04:15ZClimate change presents substantial risks to the health of Indigenous peoples. Research is needed to inform health policy and practice for managing risks, with community based adaptation (CBA) emerging as one approach to conducting research to s[...]![]()
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Martinez Cengotitabengoa, Monica ; Jose Diaz Gutierrez, Maria ; Besga, Ariadna ; Bermudez Ampudia, Cristina ; Lopez, Purificacion ; Rondon, Marta B. ; Stewart, Donna E. ; Perez, Patricia ; Gutierrez, Miguel ; Gonzalez Pinto, Ana | Elsevier | 2018-11-30T23:41:32ZObjective: Despite cautions by professional associations, benzodiazepines (BZD) and Z hypnotics (BZD/Z) are widely prescribed to older adults who are particularly susceptible to insomnia and anxiety, but who are also more sensitive to drugs adve[...]![]()
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Melanopsin is a non-image forming photoreceptor known to be present in the retina and it is considered to have light regulated tasks among other functions. In the present work, melanopsin presence in human lens epithelial cells as well as in hum[...]![]()
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García Rivas, Javier ; Súarez Barrios, Mercedes ; García Romero, Emilia ; Sánchez del Río, Manuel | Elsevier | 2020-09-15Palygorskite is a clay mineral whose structure has not been successfully deciphered, even considering the simultaneous presence of the orthorhombic and monoclinic phases within the same sample. An interesting question, which has barely been cons[...]![]()
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Staller, Alejandra ; Martínez Díaz, José J. ; Benito, Belén ; Alonso Henar, Jorge ; Hernández, Douglas ; Hernández Rey, Román ; Díaz, Manuel | Elsevier | 2016-02This paper presents the results and conclusions obtained from new GPS data compiled along the El Salvador Fault Zone (ESFZ).We calculated a GPS-derived horizontal velocity field representing the present-day crustal deformation rates in the ESFZ [...]![]()
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Gomes, C. ; López-Matayoshi, C. ; Palomo-Díez, S. ; López-Parra, A. M. ; Cuesta-Alvaro, P. ; Baeza-Richer, C. ; Gibaja, J. F. ; Arroyo-Pardo, E. | Elsevier | 2019-01-25T16:20:57ZThe nature of the sample in a forensic case is one of the most important factors, since it determines the posterior analysis, helping to define or discard its identity (like blood versus semen). A presumptive test is a qualitative analysis that [...]![]()
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Levine, Lisa D. ; Gonzales, Gustavo F. ; Tapia, Vilma L. ; Gasco, Manuel ; Sammel, Mary D. ; Srinivas, Sindhu K. ; Ludmir, Jack | Elsevier | 2019-02-06T14:52:12ZOBJECTIVE: High altitude has been implicated in a variety of adverse pregnancy outcomes including preeclampsia and stillbirth. Smaller studies show conflicting data on the association between high altitude and preterm birth (PTB). The objective[...]![]()
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Levine, Lisa D. ; Gonzales, Gustavo F. ; Tapia, Vilma L. ; Gasco, Manuel ; Sammel, Mary D. ; Srinivas, Sindhu K. ; Ludmir, Jack | Elsevier | 2020-06-10T18:11:32ZOBJECTIVE: High altitude has been implicated in a variety of adverse pregnancy outcomes including preeclampsia and stillbirth. Smaller studies show conflicting data on the association between high altitude and preterm birth (PTB). The objective[...]![]()
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Kariyawasam, R. ; Lau, R. ; Valencia, B. ; Llanos-Cuentas, A. ; Boggild, A.K. | Elsevier | 2018-10-10T23:27:56ZBackground: American tegumentary leishmaniasis (ATL) comprises a discrete set of clinical presentations of leishmaniasis endemic to Latin America and particularly Peru. Leishmania RNA virus-1 (LRV-1) is a double stranded RNA virus identified in [...]![]()
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de Ferrari, Aldo ; Miranda, J. Jaime ; Gilman, Robert H. ; Davila-Roman, Victor G. ; Leon-Velarde, Fabiola ; Rivera-Ch, Maria ; Huicho, Luis ; Bernabé-Ortiz, Antonio ; Wise, Robert A. ; Checkley, William | Elsevier | 2020-06-10T18:11:32ZBACKGROUND: Excessive erythrocytosis (EE) is a prevalent condition in populations living at high altitudes (> 2,500 m above sea level). Few large population-based studies have explored the association between EE and multiple subject-specific t[...]![]()
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Yager, Jessica E. ; Lozano Beltran, Daniel F. ; Torrico, Faustino ; Gilman, Robert H. ; Bern, Caryn | Elsevier | 2019-02-06T14:52:34ZBACKGROUND: Though the incidence of new Trypanosoma cruzi infections has decreased significantly in endemic regions in the Americas, medical professionals continue to encounter a high burden of resulting Chagas disease among infected adults. The[...]![]()
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Carrillo-Larco, Rodrigo-M. ; Miranda, J. Jaime ; Li, Xian ; Cui, Chendi ; Xu, Xiaolin ; Ali, Mohammed ; Alam, Dewan-S. ; Gaziano, Thomas-A. ; Gupta, Rajeev ; Irazola, Vilma ; Levitt, Naomi-S. ; Prabhakaran, Dorairaj ; Rubinstein, Adolfo ; Steyn, Krisela ; Tandon, Nikhil ; Xavier, Denis ; Wu, Yangfeng ; Yan, Lijing-L. | Elsevier | 2019-02-06T14:45:11ZBACKGROUND: Currently available tools for assessing high cardiovascular risk (HCR) often require measurements not available in resource-limited settings in low- and middle-income countries (LMIC). There is a need to assess HCR using a pragmatic [...]![]()
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Tramontano, Alessandra ; Veronese, Nicola ; Sergi, Giuseppe ; Manzato, Enzo ; Rodríguez-Hurtado, Diana ; Maggi, Stefania ; Trevisan, Caterina ; De Zaiacomo, Francesca ; Giantin, Valter | Elsevier | 2019-01-25T15:28:08ZAIM: To assess the prevalence of sarcopenia and associated factors in a population of older people living in a rural area of the Peruvian Andes. MATERIALS AND METHODS: The study concerned 222 people aged > /=65 years. Sarcopenia was diagnosed on[...]![]()
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Yan, Lijing-L. ; Li, Chaoyun ; Chen, Jie ; Miranda, J. Jaime ; Luo, Rong ; Bettger, Janet ; Zhu, Yishan ; Feigin, Valery ; O'Donnell, Martin ; Zhao, Dong ; Wu, Yangfeng | Elsevier | 2019-02-06T14:51:45ZAlthough stroke incidence in high-income countries (HICs) decreased over the past four decades, it increased dramatically in low- and middle-income countries (LMICs). In this review, we describe the current status of primary prevention, treatmen[...]![]()
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Novel materials, based on Mesoporous Bioactive Glasses(MBGs) in the ternary system SiO2-CaO-P2O5, decorated with (3-aminopropyl)triethoxysilane (APTES) and subsequently with amino acid Lysine (Lys), by post-grafting method on the external surfac[...]![]()
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Maldonado, A. D. ; Valdivieso, A. ; Rescia Perazzo, Alejandro Javier ; Aguilera, Ángeles | Elsevier | 2020-06-22Climate change has been related to the current loss of global biodiversity. In this paper, the effects of different scenarios of climate change on the distribution of the four classes of terrestrial vertebrate species in Andalusia (Spain) are ex[...]![]()
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Brendan Murphy, J. ; Gutiérrez Alonso, Gabriel ; Fernández Suárez, Javier ; Braid, James A. | Elsevier | 2008Northwestern Iberia preserves one of the most complete Paleozoic sequences that document the origin and development of a passive margin along the southern (Gondwanan) flank of the Rheic Ocean. In addition to a well preserved sedimentary record, [...]![]()
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In this paper we consider peculiar kinds of curved slender nearly cylindrical elastic shells enjoying rigidity properties inherited from the geometry which furnish remarkable properties of strength. In two previous papers were addressed the case[...]![]()
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In this paper we consider peculiar kinds of curved slender nearly cylindrical elastic shells enjoying rigidity properties inherited from the geometry which furnish remarkable properties of strength. In two previous papers were addressed the case[...]![]()
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We develop a procedure for assessing the environmental value of landscape mosaics that simultaneously considers the values of land use patches and the values of the boundaries between them. These boundaries indicate the ecological interactions b[...]![]()
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Herrera-Asmat, Omar ; Lubkowska, Lucyna ; Kashlev, Mikhail ; Bustamante, Carlos J. ; Guerra, Daniel G. ; Kireeva, Maria L. | Elsevier | 2019-01-25T16:03:18ZRecent publications have shown that active RNA polymerase (RNAP) from Mycobacterium tuberculosis (MtbRNAP) can be produced by expressing all four subunits in a single recombinant Escherichia coli strain [1-3]. By reducing the number of plasmids [...]![]()
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López García, Belén ; Moreno, Ana Beatriz ; San Segundo , Blanca ; De los Ríos , Vivian ; Manning, James M. ; Gavilanes, José G. ; Martínez del Pozo, Álvaro | Elsevier | 2010The mould Aspergillus giganteus produces a basic, low molecular weight protein (AFP) showing in vitro and in vivo antifungal properties against important plant pathogens. AFP is secreted as an inactive precursor containing an amino-terminal exte[...]![]()
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The Humboldt Current Large Marine Ecosystem (HCLME) covers 95% of the southeast Pacific seaboard of which the area of influence from the Humboldt Current and associated upwelling areas in the Humboldt Current System (HCS) stretches from around 4[...]![]()
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Frenk, J. ; Chen, L. ; Bhutta, Z. A. ; Cohen, J. ; Crisp, N. ; Evans, T. ; Fineberg, H. ; García, P. J. ; Ke, Y. ; Kelley, P. ; Kistnasamy, B. ; Meleis, A. ; Naylor, D. ; Pablos Méndez, A. ; Reddy, S. ; Scrimshaw, S. ; Sepúlveda, J. ; Serwadda, D. ; Zurayk, H. | Elsevier | 2019-02-22T14:54:28ZHace 100 años, diversos estudios sobre la educación de los profesionales de la salud dieron lugar a reformas innovadoras. Los nuevos retos del siglo xxiobligan a rediseñar nuevamente la educación profesional en salud. La Comisión sobre la Educac[...]![]()
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Frenk, J. ; Chen, L. ; Bhutta, Z. A. ; Cohen, J. ; Crisp, N. ; Evans, T. ; Fineberg, H. ; García, P. J. ; Ke, Y. ; Kelley, P. ; Kistnasamy, B. ; Meleis, A. ; Naylor, D. ; Pablos Méndez, A. ; Reddy, S. ; Scrimshaw, S. ; Sepúlveda, J. ; Serwadda, D. ; Zurayk, H. | Elsevier | 2019-02-22T14:54:28ZHace 100 años, diversos estudios sobre la educación de los profesionales de la salud dieron lugar a reformas innovadoras. Los nuevos retos del siglo xxiobligan a rediseñar nuevamente la educación profesional en salud. La Comisión sobre la Educac[...]![]()
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Schreve, D.C. ; Keen, D.H. ; Limondin-Lozouet, Nicole ; Auguste, Patrick ; Santisteban Navarro, Juan Ignacio ; Ubilla, Martín ; Matoshko, A. ; Bridgland, David R. ; Westaway, Rob | Elsevier | 2007Vertebrate and invertebrate faunal biostratigraphy is a well-tested method for establishing relative chronologies for fluviatile sequences that has proved useful in many parts of the world. The robust bones and teeth of large mammals are commonl[...]![]()
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An important topic in PERT networks is how to allocate the total expedition (or delay) for situations in which the project is not executed as planned. In order to do that we define a TU project game that satisfies some desirable properties from [...]![]()
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Symmetries in quantum mechanics are realized by the projective representations of the Lie group as physical states are defined only up to a phase. A cornerstone theorem shows that these representations are equivalent to the unitary representatio[...]![]()
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We study the propagation of an initial disturbance u(0)(x) of an equilibrium state s epsilon R for the scalar conservation law u(t) + phi(u)(x) = 0 in (0, + infinity) x R. We give a necessary and sufficient condition on phi for the following pro[...]![]()
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A c-edge-colored multigraph has each edge colored with one of the c available colors and no two parallel edges have the same color. A proper Hamiltonian cycle is a cycle containing all the vertices of the multigraph such that no two adjacent edg[...]![]()
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Andradas Heranz, Carlos ; Recio, Tomás ; Tabera, Luis F. ; Rafael Sendra, J. ; Villarino, Carlos | Elsevier | 2011Let K subset of R be a computable field. We present an algorithm to decide whether a proper rational parametrization of a ruled surface, with coefficients in K((i), can be properly reparametrized over a real (i.e. embedded in R) finite field ext[...]![]()
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Ancochea Bermúdez, José María ; Campoamor Stursberg, Otto Ruttwig ; Goze, M. | Elsevier | 2003-12-15Dans la variété des algèbres de Lie nilpotentes de dimension finie sur le corps des nombres complexes, l'ensemble des algèbres de Lie caractéristiquement nilpotentes n'est pas fermé. Nous montrons dans cette Note qu'il n'est pas ouvert non plus.![]()
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Arias Paniagua, Ana María ; Macorra García, José Carlos de la ; Azabal, Magdalena ; Hidalgo Arroquia, Juan José ; Peters, Ove A. | Elsevier | 2015Objectives: The aim of this study was to asses the influence of the shaping technique on incidence, intensity, duration and type of postoperative pain (PP). Methods: Root canal treatments were carried out with rtary instrumentation (n=80) during[...]![]()
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The Cameros Basin (Iberian Chain, Central Spain) developed during the latest Jurassic–Early Cretaceous in an extensional regime characterized by high rates of subsidence. Its sedimentary fill has been subdivided into eight depositional sequences[...]![]()
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Albert, R. ; Arenas Martín, Ricardo ; Gerdes, Axel ; Sánchez Martínez, Sonia ; Fernández-Suárez, J. ; Fuenlabrada Pérez, José Manuel | Elsevier | 2015-12his study focuses on the provenance of the uppermost unit of the Upper Allochthon of the Variscan belt with combined U–Pb and Lu–Hf zircon (LA-ICPMS) and Sm–Nd whole-rock analyses. This unit is represented in the Cabo Ortegal Complex (NW Iberia)[...]![]()
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The new dimorphic genus Pseudoteloceras (type-species: P. crosillense gen. et sp. nov.) is defined within the subfamily Stephanoceratinae. It constitutes the terminal step of an early Bajocian phyletic trend that produces Teloceras-like morpholo[...]![]()
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Introduction: Medical faculty plays an important role influencing for undergraduate students to carry out research, but this influence will not be adequate if they have not previously done research. Objective: To describe the characteristics of [...]![]()
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We analyse the dynamics of the non-autonomous nonlinear reaction–diffusion equation ut ?_u = f (t,x,u), subject to appropriate boundary conditions, proving the existence of two bounding complete trajectories, one maximal and one minimal. Our mai[...]![]()
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Hidalgo Román, Alberto ; García-Mouton, Cristina ; Autilio, Chiara ; Carravilla, Pablo ; Orellana Moraleda, Guillermo ; Islam, Mohammad N. ; Bhattacharya, Jahar ; Bhattacharya, Sunita ; Cruz Rodríguez, Antonio ; Pérez Gil, Jesús | Elsevier | 2020-11-24This work explores the potential for strategizing pulmonary surfactant (PS) for drug delivery over the respiratory air-liquid interface: the interfacial delivery. The efficacy of PS- and interface-assisted drug vehiculization was determined both[...]![]()
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Pulmonary surfactant is a membrane-based lipid-protein system essential for the process of breathing, which coats and stabilizes the whole respiratory surface and possesses exceptional biophysical properties. It constitutes the first barrier aga[...]![]()
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Liekkinen, Juho ; Enkavi, Giray ; Javanainen, Matti ; Olmeda Lozano, Bárbara ; Pérez-Gil, Jesús ; Vattulainen, Ilpo | Elsevier | 2020-05-02Surfactant protein B (SP-B) is essential in transferring surface-active phospholipids from membrane-based surfactant complexes into the alveolar air–liquid interface. This allows maintaining the mechanical stability of the surfactant film under [...]![]()
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Pulmonary surfactant is a lipid–protein complex that lines and stabilizes the respiratory interface in the alveoli, allowing for gas exchange during the breathing cycle. At the same time, surfactant constitutes the first line of lung defense aga[...]![]()
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Martínez Calle, Marta ; Prieto, Manuel ; Olmedo, Barbara ; Fedorov, Aleksander ; Loura, Luís M.S. ; Pérez Gil, Jesús | Elsevier | 2020-02-15Surfactant protein SP-B is absolutely required for the generation of functional pulmonary surfactant, a unique network of multilayered membranes, which stabilizes the respiratory air-liquid interface. It has been proposed that SP-B assembles int[...]![]()
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The aim of this paper is to prove that the usual topology in Q inherited from the real line is not a Mackey topology in the sense defined in [5]. To that end, we find a locally quasi-convex topology on Q/Z, the torsion group of T, which is stric[...]![]()
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It is shown that a separable variable exponent (or Nakano) function space L-p(.)(?) has a lattice-isomorphic copy of l(q) if and only if q is an element of Rp(.), the essential range set of the exponent function p(.). Consequently Rp(.) is a lat[...]![]()
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Moreno, María Nieves ; Morales Fernández, Laura ; Ruiz Medrano, Magali ; Martínez de la Casa, Jose Maria ; Madrigal Sánchez, Rebeca ; Hernández García, Elena ; Gómez de Liaño, Rosario ; García Feijoo, Julián | Elsevier | 2018-12-11Objetivo: Evaluar el efecto del glaucoma en la función visual, la calidad de vida en los niños y la calidad de vida percibida por los cuidadores en niños de hasta 16 años. Material y métodos: Se diseñó un estudio observacional y prospectivo. Se [...]![]()
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The village of Pajares de Pedraza (Segovia, Spain) is located in the floodplain of the Cega River, a left bank tributary of the Douro River. Repeated flash flood events occur in this small village because of its upstream catchment area, mountain[...]![]()
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Meinzen, Christopher ; Proaño, Alvaro ; Gilman, Robert H. ; Caviedes, Luz ; Coronel, Jorge ; Zimic, Mirko ; Sheen, Patricia | Elsevier | 2019-02-06T14:45:55ZBACKGROUND: Pyrazinamide (PZA) is the most important drug against the latent stage of tuberculosis (TB) and is used in both first and second line treatment regimens. The continued increase in multi-drug resistant TB and the prevalence of PZA res[...]![]()
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For sequence stratigraphic analysis of extensive carbonate platforms (hundreds of kilometres wide) developed in greenhouse climates on broad, passive margins, less emphasis should be placed on large-scale seismic geometries, and more attention p[...]![]()
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Spatial resilience quantification can be a useful tool for land planning and management in agricultural systems to predict the appropriate control of disturbances such as pest infections. We proposed an index of spatial resilience based on lands[...]![]()
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We study the equilibrium dynamics of the relative phase in a superconducting Josephson link taking into account the quantum ?uctuations of the electromagnetic vacuum. The photons act as a superohmic heat bath on the relative Cooper pair number a[...]![]()
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Many stochastic systems, including biological applications, use Markov chains in which there is a set of absorbing states. It is then needed to consider analogs of the stationary distribution of an irreducible chain. In this context, quasi-stati[...]![]()
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An example of a Frechet space E is given such that the space of n-homogeneous continuous polynomials on E, endowed with any of the natural topologies usually considered on it, is quasinormable for every n is an element of N. This space has the p[...]![]()
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Thick laminar calcrete profiles are common on the surface of the eastern Canary Islands of Lanzarote and Fuerteventura. This paper reports the study of one profile from Lanzarote (Macher profile) and one from Fuerteventura (Tef|¨a profile). Thes[...]![]()
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The Quaternary sedimentary record of Sal Island includes marine and related aeolian and alluvial fan deposits. The substratum of the island is volcanic, with ages between 25 and 0.6 Ma. Quaternary marine units generally occur as raised marine te[...]![]()
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Soit E un fibre vectoriel stable sur l'espace projectif P'. Les droites de saut de E d'ordre donné, stratifient la variété des droites. On utilise un théorème de Porteous pour donner des informations numériques sur les strates. En particulier on[...]![]()
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We consider a queueing system where a customer who finds all channels busy must decide either to join the queue or to retry after an exponentially distributed time. The performance of the system can be approximated by using the RTA approximation[...]![]()
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España es uno de los países europeos con mayor prevalencia de enfermedad renal crónica, con una población de más de 4 millones de pacientes. De estos, se hallan en tratamiento sustitutivo renal 31.735 entre los programas de trasplante renal, diá[...]![]()
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We characterize the positive radial continuous and rotation invariant valuations V defined on the star bodies of Rn as the applications on star bodies which admit an integral representation with respect to the Lebesgue measure. That is,V(K)=?Sn?[...]![]()
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We show that a radial continuous valuation defined on the n-dimensional star bodies extends uniquely to a continuous valuation on the n-dimensional bounded star sets. Moreover, we provide an integral representation of every such valuation, in te[...]![]()
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We study in this paper the asymptotic behaviour of solutions of a nonlinear Fokker-Plank equation. Such an equation describes the evolution of radiation for a gas of photons, which interacts with electrons by means of Compton scattering and Brem[...]![]()
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Zazo Cardeña , Caridad ; Goy Goy, José Luis ; Hillaire-Marcel, Claude ; Guillot, Pierre-Yvot ; Soler Javaloyes, Vicente ; González Delgado, José Ángel ; Dabrio, Cristino J. ; Ghaleb, B. | Elsevier | 2002Systematic mapping and morphosedimentary analysis of Fuerteventura and Lanzarote Islands supported by laboratory techniques (U-series mostly by TIMS, 14C analysis and allo-isoleucine measurements on biogenic carbonates from raised marine deposit[...]![]()
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García Montero, María ; Rico del Viejo, Laura ; Llorens Quintana, Clara ; Lorente Velázquez, Amalia ; HernandezVerdejo, José Luis ; Madrid Costa, David | Elsevier | 2018-12-23Purpose: The aim of the current study is to assess, using new technologies, the interaction of four monthly silicone hydrogel contact lenses on the ocular surface and the comfort over 15 days of use. Methods: Prospective cross-over, randomized a[...]![]()
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García Montero, María ; Rico del Viejo, Laura ; Llorens Quintana, Clara ; Lorente Velázquez, Amalia ; Hernández Verdejo, José Luis ; Madrid Costa, David | Elsevier | 2018-12-23Purpose: The aim of the current study is to assess, using new technologies, the interaction of four monthly silicone hydrogel contact lenses on the ocular surface and the comfort over 15 days of use. Methods: Prospective cross-over, randomized a[...]![]()
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The study was designed to assess acceptability and side-effects of consumption of sacha inchi oil, rich in alpha-linolenic acid and sunflower oil, rich in linoleic acid, in adult human subjects. Thirty subjects received 10 or 15ml daily of sacha[...]![]()
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Pfeiffer, Norbert ; García Feijoo, Julián ; Martínez de la Casa, Jose Maria ; Larrosa Povés, José Manuel ; Fea, Antonio ; Lemij, Hans ; Gandolfi, Stefano ; Schwenn, Oliver ; Lorenz, Katrin ; Samuelson, Thomas W. | Elsevier | 2015-07Purpose: To assess the safety and effectiveness of the Hydrus Microstent (Ivantis, Inc, Irvine, CA) with concurrent cataract surgery (CS) for reducing intraocular pressure (IOP) in open-angle glaucoma (OAG). Design: Prospective, multicenter, ran[...]![]()
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Murad, M. H. ; Guyatt, G. H. ; Domecq, J. P. ; Vemooij, R. W. M. ; Erwin, P. J. ; Meerpohl, J. J. ; Prutsky, G. J. ; Akl, E. A. ; Mueller, K. ; Bassler, D. ; Schandelmaier, S. ; Walter, S. D. ; Busse, J. W. ; Kasenda, B. ; Pagano, G. ; Pardo-Hernandez, H. ; Montori, V. M. ; Wang, Z. ; Briel, M. | Elsevier | 2019-01-25T16:36:28ZObjective: We explored how investigators of ongoing or planned trials respond to the publication of a trial stopped early for benefit addressing a similar question. Study Design and Setting: We searched multiple databases from the date of public[...]![]()
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Martínez Cisuelo, V. ; Gómez, J. ; García Junceda, I. ; Naudi, Alba ; Cabré, R. ; Mota Martorell, N. ; López Torres, Mónica ; González Sánchez, Mónica ; Pamplona, R. ; Barja de Quiroga, Gustavo | Elsevier | 2016-10Rapamycin consistently increases longevity in mice although the mechanism of action of this drug is unknown. In the present investigation we studied the effect of rapamycin on mitochondrial oxidative stress at the same dose that is known to incr[...]![]()
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Aranbarri, Josu ; González Sampériz, Penélope ; Moreno, Ana ; Valero-Garcés, Blas ; Moreno, Ana ; Gil-Romera, Graciela ; Sevilla-Callejo, Miguel ; García-Prieto, Eduardo ; Di Rita, Federico ; Mata, M. Pilar ; Morellón, Mario ; Magri, Donatella ; Rodríguez-Lázaro, Julio ; Carrión, José S. | Elsevier | 2014Palynological, sedimentological and geochemical analyses performed on the Villarquemado paleolake sequence (987 m a.s.l, 40°30?N; 1°18?W) reveal the vegetation dynamics and climate variability in continental Iberia over the last 13,500 cal yr BP[...]![]()
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Glass, Roger I. ; García, Patricia J. ; Belter, Christopher W. ; Livinski, Alicia A. ; Leon-Velarde, Fabiola | Elsevier | 2018-12-03T17:02:46Z![]()
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Poor vision in low light is a common complaint of elderly people. This poorly understood phenomenon is likely to involve both receptoral and post receptoral mechanisms. We investigated the recovery of contrast thresholds for sine-wave gratings o[...]![]()
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Esteban Fernández de Ávila, Berta ; Zhao, Mingjiao ; Campuzano, Susana ; Ricci, Francesco ; Pingarrón Carrazón, José Manuel ; Mascini, Marcelo ; Wang, Joseph | Elsevier | 2017-05-15A dynamic micromotor-based immunoassay, exemplified by cortisol detection, based on the use of tubular micromotors functionalized with a specific antibody is described. The use of antibody-functionalized micromotors offers huge acceleration of b[...]![]()
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In this paper we obtain the rates of convergence of the algorithms given in [13] and [14] for an automatic computation of the centered Hausdorff and packing measures of a totally disconnected self-similar set. We evaluate these rates empirically[...]![]()
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Díez Fernández, Rubén ; Rubio Pascual, Francisco J. ; Martín Parra, Luis Miguel | Elsevier | 2019-03This contribution discusses about the rheological, kinematic and dynamic frameworks necessary to produce recumbent and upright folds from syn-orogenic granitic massifs that were formed during an early stage of magma genesis related to the onset [...]![]()
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In this paper we present results of a study of the crystallisation behaviour of the dolomite-analogues norsethite and PbMg (CO3)2 at room temperature and atmospheric pressure. Whereas precipitation of norsethite was previously obtained by mixing[...]![]()
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Casado González, Miguel Ángel ; Ciriano, Miguel A. ; Lahoz, Fernando J. ; Oro, Luis A. ; Pérez Torrente, Jesús J. | Elsevier | 2016-06-15Treatment of heterobimetallic sulfido-bridged complexes [Cp(acac)Ti(m3-S)2{M(cod)}2] (M ¼ Rh (1), Ir(2)) with the organic acids CX3COOH (X ¼ F, H) forms the corresponding acetate derivatives [Cp(CX3COO)Ti(m3-S)2{M(cod)}2] (X ¼ F, M ¼ Rh (3), Ir [...]![]()
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There have been quite a few proposals for behavioural equivalences for concurrent processes, and many of them are presented in Van Glabbeek’s linear time-branching time spectrum. Since their original definitions are based on rather different ide[...]![]()
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Let X be a separable Banach space with a separating polynomial. We show that there exists C > = 1 (depending only on X) such that for every Lipschitz function f : X -> R, and every epsilon > 0, there exists a Lipschitz, real analytic function [...]![]()
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We investigate the behaviour by general J- and K-methods of certain closed operator ideals. In particular, the results apply to weakly compact operators, Rosenthal operators and Banach–Saks operators.![]()
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We prove that if T: A0 ? B0 is compact and T: A1 ? B1 is compact (or T: A1 ? B1 is bounded and, then given any ? and q with 0![]()
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We study real algebraic plane curves, at an elementary level, using as little algebra as possible. Both cases, affine and projective, are addressed. A real curve is infinite, finite or empty according to the fact that a minimal polynomial for th[...]![]()
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This paper provides an elementary exposition of affine and projective real plane curves. Where possible, elementary proofs are given, but to some extent, one must make use of results from algebraic geometry (over the complex numbers) and real al[...]![]()
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The main goal of this paper is to prove that for each n > 2, every sequence of integers satisfying Dold’s congruences is realized as the sequence of fixed point indices of the iterates of an orientation preserving Rn-homeomorphism at an isolate[...]![]()
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Lomoschitz, Alejandro ; Sanchez Marco, Antonio ; Huertas Coronel, María José ; Betancort, Juan F. ; Arnau, Isern ; Sanz, Elena ; Meco, Joaquín | Elsevier | 2016-11The Famara massif, in the north of Lanzarote Island, constitutes the remains of a former island inhabited by the oldest known vertebrate fauna of the Canary archipelago off the coast of Africa. In this study, new ages are offered for the underly[...]![]()
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Dry eye syndrome is a common tears and ocular surface multifactorial disease, described by changes in the ocular surface epithelia related to reduced tears quantity and ocular surface sensitivity, leading to inflammatory reaction. Managing the e[...]![]()
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Reductive acetylation of the lipoyl domain (E2plip) of the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase multienzyme complex of Escherichia coli is catalysed specifically by its partner pyruvate decarboxylase (E1p), and[...]![]()
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Karátson, D. ; Yepes, J. ; Favalli, M. ; Rodríguez-Peces, Martin Jesús ; Fornaciai, A. | Elsevier | 2016-01Original volcanic edifices of two successive stages of Gran Canaria are reconstructed using a geomorphometric analysis of existent or restored paleosurfaces. In the reconstruction, surface fitting was applied preferably to planèzes (i.e. triangu[...]![]()
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Independent component analysis (ICA) has been proven useful for suppression of artifacts in EEG recordings. It involves separation of measured signals into statistically independent components or sources, followed by rejection of those deemed ar[...]![]()
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This work studies the evolution of IGCC slag grains within a ceramic matrix fired at different temperatures to investigate the effect of using IGCC slag as a degreaser. Pressed ceramic specimens from two clay mixtures are used in this study. The[...]![]()
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Residency at high altitude (HA) demands adaptation to challenging environmental conditions with hypobaric hypoxia being the most important one. Epidemiological and experimental data suggest that chronic exposure to HA reduces cancer mortality an[...]![]()
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Organized tours to watch wildlife are popular recreational and educational activities, in which the visitor expectative (to observe as many and as diverse animals as possible) runs parallel to conservation purposes. However, the presence of visi[...]![]()
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Ferrater, Marta ; Ortuño, María ; Masana, Eulàlia ; Pallàs, Raimon ; Perea Manea, Hector ; Baize, Stephane ; García Meléndez, Eduardo ; Martínez Díaz, José J. ; Echeverria, Anna ; Rockwell, Thomas K. ; Sharp, Warren D. ; Medialdea, Alicia ; Rhodes, Edward J. | Elsevier | 2016-06hree-dimensional paleoseismology in strike-slip faults with slip rates less than 1 mm per year involves a greatmethodological challenge. We adapted 3D trenching to track buried channels offset by the Alhama de Murciaseismogenic left-lateral stri[...]![]()
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Román-Dañobeytia, F. ; Huayllani, M. ; Michi, A. ; Ibarra, F. ; Loayza-Muro, R. ; Vázquez, T. ; Rodríguez, L. ; García, M. | Elsevier | 2019-02-22T14:55:02ZGlobal demand for gold has led to a massive increase in mining activity around the world. During the last decade, gold mining grew significantly in the Amazon becoming a major driver for land degradation and heavy metal contamination. However, f[...]![]()
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Understanding how fossil assemblages were formed and which species modified the bones recovered in archaeological sites is no easy task. Nevertheless, during recent decades taphonomists have been working on the study of living carnivores in orde[...]![]()
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Egea-González, Isabel ; Jiménez Díaz, Alberto ; Parro, Laura M. ; Mansilla, Federico ; Holmes, James A. ; Lewis, Stephen R. ; Patel, Manish R. ; Ruiz Pérez, Javier | Elsevier | 2019Elysium Planitia and Oxia Planum are plains located near the Martian dichotomy. Lately, both regions have been extensively analyzed due to the major role that they play in the InSight and ExoMars missions. InSight landed in Elysium Planitia and [...]![]()
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Lazo-Porras, Maria ; Bernabé-Ortiz, Antonio ; Ruiz-Alejos, Andrea ; Smeeth, Liam ; Gilman, Robert H. ; Checkley, William ; Malaga, German ; Jaime Miranda, J. | Elsevier | 2019-12-06T21:04:48ZAIMS: This study aimed (1) to estimate the prevalence of prediabetes according to different definitions, (2) to evaluate regression to normal glucose levels and progression towards T2DM, and (3) to determine factors associated with regression an[...]![]()
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Lazo-Porras, Maria ; Bernabé-Ortiz, Antonio ; Ruiz-Alejos, Andrea ; Smeeth, Liam ; Gilman, Robert H. ; Checkley, William ; Malaga, German ; Miranda, J. Jaime | Elsevier | 2020-07-14T00:02:30ZAIMS: This study aimed to (1) estimate the prevalence of prediabetes according to different definitions, (2) evaluate regression to normal glucose levels and progression towards T2DM, and (3) determine factors associated with regression and prog[...]![]()
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We study the regularity of the solution to the Reynolds equation for incompressible and compressible fluids when the gap between the lubricated surfaces, “h(x,y)”, presents a discontinuity in a two-dimensional bounded domain. As in the one-dimen[...]![]()
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Diego García, Laura de ; Ramírez Escudero, Mercedes ; Sebastián Serrano, Álvaro ; Díaz Hernández, Juan Ignacio ; Pintor, Jesús ; Lucas Lozano, José J. ; Díaz Hernández, Miguel | Elsevier | 2017-01The Ubiquitin-Proteasome System (UPS) is essential for the regulation of the cellular proteostasis. Indeed, it has been postulated that an UPS dysregulation is the common mechanism that underlies several neurological disorders. Considering that [...]