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Autor Martínez del Pozo, Álvaro |
Documentos disponibles escritos por este autor (55)
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Álvarez García, Elisa ; Diago Navarro, Elizabeth ; Herrero Galán, Elías ; García Ortega, Lucía ; López Villarejo, Juan ; Olmo López, Nieves ; Díaz Orejas, Ramón ; Gavilanes, José G. ; Martínez del Pozo, Álvaro | Elsevier | 2011Fungal ribotoxins are toxic secreted ribonucleases that cleave a conserved single phosphodiester bond located at the sarcin/ricin loop of the larger rRNA. This cleavage inactivates ribosomes leading to protein biosynthesis inhibition and cell de[...]![]()
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Olombrada, Miriam ; Peña, Cohue ; Rodríguez Galán, Olga ; Klingauf Nerurkar, Purnima ; Portugal Calisto, Daniela ; Oborská Oplová, Michaela ; Altvater, Martin ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; De la Cruz, Jesús ; García Ortega, Lucía ; Govind Panse, Vikram | Elsevier | 2020-04-04The ribotoxin -sarcin belongs to a family of ribonucleases that cleave the sarcin/ricin loop (SRL), a critical functional rRNA element within the large ribosomal subunit (60S), thereby abolishing translation. Whether -sarcin targets the SRL only[...]![]()
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Olombrada, Miriam ; Peña, Cohue ; Rodríguez Galán, Olga ; Klingauf Nerurkar, Purnima ; Portugal Calisto, Daniela ; Oborská Oplová, Michaela ; Altvater, Martin ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Cruz, Jesús de la ; García Ortega, Lucía ; Govind Panse, Vikram | Oxford University Press | 2020The ribotoxin -sarcin belongs to a family of ribonucleases that cleave the sarcin/ricin loop (SRL), a critical functional rRNA element within the large ribosomal subunit (60S), thereby abolishing translation. Whether -sarcin targets the SRL only[...]![]()
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Carreras Sangrà, Nelson ; Álvarez García, Elisa ; Herrero Galán, Elías ; Tomé, Jaime ; Lacadena, Javier ; Alegre Cebollada, Jorge ; Oñaderra, Mercedes ; Gavilanes, José G. ; Martínez del Pozo, Álvaro | Bentham Science Publishers Ltd. | 2008Ribotoxins constitute a family of toxic extracellular fungal RNases that exert a highly specific activity on a conserved region of the larger molecule of rRNA, known as the sarcin–ricin loop. This cleavage of a single phosphodiester bond inactiv[...]![]()
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García Linares, Sara ; Palacios Ortega, Juan ; Yasuda, Tomokazu ; Astrand, Mia ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | Elsevier | 2016-03-11Sticholysin I and II (StnI and StnII) are pore-forming toxins that use sphingomyelin (SM) for membrane binding. We examined how hydrogen bonding among membrane SMs affected the StnI- and StnII-induced pore formation process, resulting in bilayer[...]