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Introduction: Nanocarriers have emerged as a powerful alternative for cancer therapy.Indeed, they are promising candidates to tackle the acquired resistance of surviving cells against antiproliferative drugs – the so-called multidrug resistance [...]texto impreso
Castillo, Rafael R. ; Lozano Borregón, Daniel ; González, Blanca ; Manzano García, Miguel ; Izquierdo-Barba, Isabel ; Vallet Regí, María | Taylor & Francis | 2019-03-22Introduction: Mesoporous silica nanoparticles (MSNs) are outstanding nanoplatforms for drug delivery. Herein, the most recent advances to turn MSN-based carriers into minimal side effect drug delivery agents are covered. Areas covered: This revi[...]texto impreso
Jedidi, Ines ; Cruz, Alejandra ; González Jaén, María Teresa ; Said, Salem | Taylor & Francis | 2016-11-02Occurrence of aflatoxins (AFs) AFB1, AFB2, AFG1, AFG2 and ochra toxin A (OTA) was studied in 65 samples of stored and freshly harvested wheat, barley and maize collected in Tunisia. The mycotoxins were simultaneously extracted and quantified by [...]texto impreso
Galindo Francisco, Mª del Carmen ; Pankhurst, R.J. ; Casquet, César ; Coniglio, Jorge ; Baldo, Edgardo G. ; Rapela, Carlos W. ; Saavedra, Julio | Taylor & Francis | 1997Fluorite mineralization at the La Nueva and Bubu mines yields Sm-Nd ages of 131 ± 22 and 117 ± 26 Ma, respectively. Thus, the mineralization most probably is related to a late Gondwanian (Lower Cretaceous) extensional and magmatic event that aff[...]texto impreso
This paper analyses which districts are targeted by Spanish political parties in their electoral campaigns. We find that the major Spanish parties - PP and PSOE - mobilise districts where they are more likely to win a new seat or are in danger o[...]texto impreso
Acosta Gallo, Belén ; Casado González, Miguel Ángel ; Montalvo, J. ; Diaz Pineda, Francisco | Taylor & Francis | 2011-09Below-ground biomass might play an important role in the persistence of grasslands. The summertime water stress of Mediterranean grasslands very much accounts for annual plants in their communities. These plants die off in summer, and the soil s[...]texto impreso
Fernández López, Sixto Rafael ; Henriques, María Helena Paiva ; Mangold, Charles | Taylor & Francis | 2006The Cabo Mondego outcrops exposed along the cliffs, on the western margin of the Iberian Plate, show an expanded stratigraphic section of Lower Bathonian deposits containing abundant ammonoids. Upper Bajocian deposits correspond to similar facie[...]texto impreso
Bas Auran, in south-eastern France, is the candidate area for Global Boundary Stratotype Section and Point (GSSP) of the base of the Bathonian Stage (Middle Jurassic). In the Bas Auran area, upper Bajocian and lower Bathonian deposits are made u[...]texto impreso
Two-part models based on generalized linear models are widely used in insurance rate-making for predicting the expected loss. This paper explores an alternative method based on quantile regression which provides more information about the loss d[...]texto impreso
The purpose of this paper is to study the problem (P) ??u+u??=f in ?, u=0 on ??, u???L1(?), u> 0 in ?, where ? is a bounded smooth open set of RN, f?0, f?L1(?) and 0texto impreso
Based on a data set of 115 economies, this article empirically investigates the relation between public debt and economic growth. Using the World Bank’s classification for income groups, we initially find that those countries that present the lo[...]texto impreso
Acosta-González, Eduardo ; Fernández-Rodríguez, Fernando ; Sosvilla-Rivero, Simón | Taylor & Francis | 2014-03Using a statistical methodology guided only by data and based on a genetic algorithm, we select the best econometric model for explaining the determinants of the size of the shadow economy, its main determinants being: taxes on capital gains of [...]texto impreso
We show the rigidity of a parameterized family of solvable Leibniz non-Lie algebras in arbitrary dimension, obtaining an irreducible component in the variety L epsilon(n) that does not intersect the variety of Lie algebras non-trivially. Moreove[...]texto impreso
An iterative strategy for the reconstruction of objects buried in a medium and the identification of their material parameters is analysed. The algorithm alternates guesses of the domains using topological derivatives with corrections of the par[...]texto impreso
Wetlands are vulnerable to groundwater extraction, which has proven detrimental to aquatic ecosystems around the planet. As wetlands rank among the world’s most endangered ecosystems, versatile strategies are required to protect them. This paper[...]
