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Esteban Fernández, Diego ; Verdaguer, J.M. ; Ramírez, R. ; Palacios Corvillo, María A. ; Gómez Gómez, M. Milagros | Oxford Academic | 2008-03Antitumoral Pt-containing drugs present side effects like nephrotoxicity and ototoxicity. Several systematic experiments have been carried out with Wistar rats treated with cisplatin, carboplatin, and oxaliplatin to study Pt-drugs accumulation a[...]texto impreso
Ramírez Camacho, R. ; Esteban Fernández, Diego ; Verdaguer, J.M. ; Gómez Gómez, M. Milagros ; Trinidad, A. ; García Berrocal, J.R. ; Palacios Corvillo, M. Antonia | Taylor and Francis | 2008Conclusion. Inductively coupled plasma mass spectrometry (ICP-MS) can be applied to organic tissues obtained from experimental animals. Hearing loss does not correlate with the platinum (Pt) concentration found in the inner ear. Drug structure a[...]texto impreso
Esteban Fernández, Diego ; Gómez Gómez, M.Milagros ; Cañas, Benito ; Verdaguer, J.M. ; Ramírez, R. ; Palacios Corvillo, M.Antonia | Elsevier | 2007Chemical compounds containing platinum have been employed since 1978 as drugs to beat certain type of tumours. Nevertheless, besides of their exceptional antitumoral properties, these drugs also have important deleterious side effects, such as, [...]
