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Título:
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The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan
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Autores:
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Garrido Tarrio, Antonio ;
Cruces, Julia ;
Ceprián, Noemí ;
Díaz del Cerro, E. ;
Félix, J. ;
Fuente del Rey, Mónica de la
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Tipo de documento:
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texto impreso
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Editorial:
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Elsevier, 2020-04-10
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Dimensiones:
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application/pdf
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Nota general:
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info:eu-repo/semantics/restrictedAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Medicina: Inmunología
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Materia = Ciencias Biomédicas: Biología: Fisiología animal
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Tipo = Artículo
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Resumen:
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Adult prematurely aging mice (PAM) show behavioral deterioration, premature immunosenescence and increased oxidative stress, impairments that are associated with their shorter lifespan, compared to the corresponding exceptional non-prematurely aging mice (ENPAM). When PAM live in a predominantly ENPAM environment (2/5, respectively) they exhibit an improvement of immunity and redox state in their spleen and thymus leukocytes, and an increased lifespan. Nevertheless, it is unknown if other PAM/ENPAM ratios could affect behavioral and peritoneal leukocyte functions of PAM and change their lifespan. ENPAM and PAM were divided into the following groups: C-ENPAM (8 ENPAM in the cage); C-PAM (8 PAM in the cage); ENPAM > 50% and PAM 50% and ENPAM 50%, PAM = 50% and PAM
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En línea:
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https://eprints.ucm.es/id/eprint/60825/1/Garrido%2C%20A.%20et%20al.%202020.%20The%20ratio%20of%20prematurely%20aging.....pdf
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