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Autor Pintor, Jesús |
Documentos disponibles escritos por este autor (65)
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The eye is continuously exposed to solar UV radiation and pollutants, making it prone to oxidative attacks. In fact, oxidative damage is a major cause of age-related ocular diseases including cataract, glaucoma, age-related macular degeneration [...]![]()
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Carracedo Rodríguez, Juan Gonzalo ; Crooke, Almudena ; Guzmán Aranguez, Ana María ; Pintor, Jesús | Elsevier | 2016-07-14Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substance[...]![]()
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Andrés Guerrero, Vanessa ; Molina Martínez, Irene Teresa ; Peral Cerdá, Assumpta ; De las Heras Polo, Beatriz ; Pintor, Jesús ; Herrero Vanrell, Rocío | Association for Research in Vision and Ophthalmology (ARVO) | 2011-03Purpose.: 5-Methoxy-carbonylamino-N-acetyltryptamine (5-MCA-NAT, a melatonin receptor agonist) produces a clear intraocular pressure (IOP) reduction in New Zealand White rabbits and glaucomatous monkeys. The goal of this study was to evaluate wh[...]![]()
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TRPV4 activation triggers the release of melatonin from human non-pigmented ciliary epithelial cells
Melatonin is a neurohormone mainly produced in the pineal gland; nevertheless, various ocular structures such as the ciliary body, lens and the retina produce it. One of the roles of melatonin in the eye is the modulation of intraocular pressure[...]![]()
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Alkozi, Hanan Awad ; Pérez de Lara, María Jesús ; Sánchez Naves, Juan ; Pintor, Jesús | MDPI | 2017-04Melatonin is a molecule which has gained a great deal of interest in many areas of science; its synthesis was classically known to be in the pineal gland. However, many organs synthesize melatonin, such as several ocular structures. Melatonin is[...]