Información del autor
Documentos disponibles escritos por este autor (65)
Añadir el resultado a su cesta Hacer una sugerencia Refinar búsqueda
texto impreso
Awad Alkozi, Hanan ; Navarro, Gemma ; Aguinaga, David ; Reyes-Resina, Irene ; Sánchez Naves, Juan ; Pérez de Lara, María Jesús ; Franco, Rafael ; Pintor, Jesús | The British Pharmacological Society / Wiley-Blackwell | 2020-01-04Background and Purpose: Often, glaucoma courses with elevated eye hydrostatic pression, which is regulated by endogenous melatonin. Via ?1?adrenoceptor activation, phenylephrine increases cytoplasmic [Ca2+] that is detrimental in glaucoma. The a[...]texto impreso
Colligris, Basilio ; Crooke, Almudena ; Huete Toral, Fernando ; Pintor, Jesús | Taylor & Francis | 2014-07Introduction: Dry eye disease is a common disorder provoking changes in tear film and ocular surface. Untreated dry eye could cause ocular infections, corneal ulcer and blindness. Only a few drugs are authorized so far for the treatment of dry e[...]texto impreso
Loma Lozano, Patricia ; Guzmán Aránguez, Ana Isabel ; Pérez de Lara, María Jesús ; Pintor, Jesús | Spanish General Council of Optometrists | 2017-11Purpose/aim: Glaucoma consists of a group of progressive optic neuropathies that are characterized by degeneration of the optic nerve and irreversible visual filed loss. Elevated intraocular pressure is the only proven treatable risk factor and [...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Gonzalez-Meijome, Jose Manuel ; Pintor, Jesús | The Association for Research in Vision and Ophthalmology, Inc. | 2012-07Purpose.: To evaluate the levels of dinucleotides diadenosine tetraphosphate (Ap4A) and diadenosine pentaphosphate (Ap5A) in tears of patients wearing rigid gas permeable (RGP) contact lenses on a daily wear basis and of patients wearing reverse[...]texto impreso
Martínez Águila, Alejandro ; Fonseca Vázquez, Begoña ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | 2020-07-29Purpose: The objective of this study was to evaluate the changes in the melatoninergic receptors of DBA/2J and C57BL/6J mice with the development of glaucoma. DBA/2J mice are widely used to study the physiopathology of glaucoma due to the simila[...]texto impreso
Fonseca Vázquez, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Pintor, Jesús | Frontiers Media | 2017-10-10Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal mode[...]texto impreso
texto impreso
Mediero Muñoz, Aránzazu ; Guzmán Aránguez, Ana Isabel ; Crooke, Almudena ; Peral Cerdá, Assumpta ; Pintor, Jesús | The Association for Research in Vision and Ophthalmology, Inc. | 2008-11Purpose. To investigate the role of ERK1/2 and RhoA/ROCK intracellular pathways in the modification of corneal re-epithelialization when stimulated by the diadenosine polyphosphates Ap4A and Ap3A. Methods. In wounded confluent SIRC (Statens Seru[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Cacho, Isabel ; Sánchez Naves, Juan ; Pintor, Jesús | John Wiley & Sons Ltd. | 2014-02Purpose:? To study the concentrations of diadenosine polyphosphates in the ocular surface after PRK and LASIK. Methods:? Sixty-one patients (30 males and 31 females) with ages ranging from 20 to 63 (34.04 ± 9.13 years) were recruited in Balear I[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Peral Cerdá, Assumpta ; Pintor, Jesús | The Association for Research in Vision and Ophthalmology, Inc. | 2010-11Purpose.: To analyze the levels of diadenosine tetraphosphate (Ap4A) and diadenosine pentaphosphate (Ap5A) in tears of subjects with Sjögren syndrome and to compare them with those in a control group. Methods.: Twelve subjects with a diagnosis o[...]texto impreso
Peral Cerdá, Assumpta ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | Wiley-Blackwell | 2015-08Purpose To quantify diadenosine polyphosphate levels in tears of congenital aniridia patients to estimate the ocular surface changes associated with congenital aniridia compared to normal individuals. Methods Fifteen patients diagnosed with cong[...]texto impreso
Fonseca, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Pintor, Jesús | Springer | 2016-11Glaucoma is a neurodegenerative disease that produces blindness. The main factor associated with this disease is an abnormally elevated intraocular pressure (IOP). To date, some attempts have been made to demonstrate the role of nucleotides modu[...]texto impreso
Loma Lozano, Patricia ; Guzmán Aránguez, Ana Isabel ; Pérez de Lara, María Jesús ; Pintor, Jesús | Elsevier | 2015-05The effect of the dinucleotide P1, P4-Di (adenosine-5') tetraphosphate (Ap4A) in improving adrenergic anti-glaucomatous delivery by modifying the tight junction proteins of the corneal epithelium was evaluated. Stratified human corneal epithelia[...]texto impreso
Loma Lozano, Patricia ; Guzmán Aránguez, Ana Isabel ; Pérez de Lara, María Jesús ; Pintor, Jesús | The British Pharmacological Society / Wiley-Blackwell | 2015-02BACKGROUND AND PURPOSE: Here, we have studied the effects of the dinucleotide P1, P4-Di (adenosine-5?) tetraphosphate (Ap4A) on corneal barrier function conferred by the tight junction (TJ) proteins and its possible involvement in ocular drug de[...]texto impreso
García Porta, Nery ; Rico del Viejo, Laura ; Martín Gil, Alba ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús ; Gonzalez-Meijome, Jose Manuel | Hindawi Publishing Corporation | 2016-08Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK). Materials and Methods. This was a prospecti[...]
