Información del autor
Autor Pintor, Jesús |
Documentos disponibles escritos por este autor (65)
Añadir el resultado a su cesta Hacer una sugerencia Refinar búsqueda
texto impreso
texto impreso
Dry eye syndrome is a common tears and ocular surface multifactorial disease, described by changes in the ocular surface epithelia related to reduced tears quantity and ocular surface sensitivity, leading to inflammatory reaction. Managing the e[...]texto impreso
Diego García, Laura de ; Ramírez Escudero, Mercedes ; Sebastián Serrano, Álvaro ; Díaz Hernández, Juan Ignacio ; Pintor, Jesús ; Lucas Lozano, José J. ; Díaz Hernández, Miguel | Elsevier | 2017-01The Ubiquitin-Proteasome System (UPS) is essential for the regulation of the cellular proteostasis. Indeed, it has been postulated that an UPS dysregulation is the common mechanism that underlies several neurological disorders. Considering that [...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Serramito Blanco, María ; Martín Gil, Alba ; Wang, Zicheng ; Carballo Álvarez, Jesús ; Pintor, Jesús | Lippincott Williams & Wilkins | 2016-02Purpose: To evaluate the most important signs of dry eye, such as osmolarity, inflammation, and diadenosine tetraphosphate (Ap4A) concentration before and after wearing scleral lenses for 8 h in keratoconus patients. Methods: A pilot, experiment[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Recchioni, Alberto ; Alejandre Alba, Nicolás ; Martín Gil, Alba ; Batres Valderas, Laura ; Jiménez Alfaro-Morote, Ignacio ; Pintor, Jesús | Taylor & Francis | 2017Purpose: Based on the relationship between keratoconus and dry eye, the aim of this study was to evaluate changes in signs and symptoms of dry eye in keratoconus patients before and after intrastromal corneal ring surgery. Methods: Fifteen kerat[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Recchioni, Alberto ; Alejandre Alba, Nicolás ; Martín Gil, Alba ; Crooke, Almudena ; Jiménez Alfaro-Morote, Ignacio ; Pintor, Jesús | Taylor & Francis | 2015-11Purpose: To compare signs and symptoms of dry eye in keratoconus (KC) patients versus healthy subjects. Methods: A total of 15 KC patients (KC group, n?=?15 eyes) and 16 healthy subjects (control group, 16 eyes) were enrolled in this study. The [...]texto impreso
Rivas Santisteban, Rafael ; Reyes Resina, Irene ; Raich, Iu ; Pintor, Jesús ; Alkozi, Hanan Awad ; Navarro Brugal, Gemma ; Franco Fernández, Rafael | San Antonio TX | 2019-12-15This is a pre-registered study, i.e. a study whose hypotheses and experiments designed to address these hypotheses have been deposited in a database before starting the experiments. The study aims at assessing the Gs versus Gi coupling and the p[...]texto impreso
Acosta Boj, Mª Carmen ; Peral Cerdá, Assumpta ; Luna García, Carolina ; Pintor, Jesús ; Belmonte, Carlos ; Gallar Martínez, Juana | The Association for Research in Vision and Ophthalmology, Inc. | 2004-07Purpose. To measure the increase in tear secretion evoked by selective stimulation of the different populations of sensory receptors of the cornea and conjunctiva by using moderate and intense mechanical, chemical, and cold stimuli. Methods. Six[...]texto impreso
Fernández Arroyo, Salvador ; Huete Toral, Fernando ; Pérez de Lara, María Jesús ; Cádiz Gurrea, María de la Luz ; Legeai Mallet, Laurence ; Micol, Vicente ; Segura Carretero, Antonio ; Joven, Jorge ; Pintor, Jesús | Taylor & Francis | 2015-10-05Background: Imbalances in the functional binding of fibroblast growth factors (FGFs) to their receptors (FGFRs) have consequences for cell proliferation and differentiation that in chondrocytes may lead to degraded cartilage. The toxic, proinfla[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Gonzalez-Meijome, Jose Manuel ; Martín Gil, Alba ; Carballo Álvarez, Jesús ; Pintor, Jesús | Elsevier | 2016-10Purpose: To evaluate the signs and symptoms of dry eye and dinucleotide secretion in tears of keratoconus patients (KC) and the potential effect of rigid gas permeable (RGP) contact lens wear. Methods: Twenty-three KC patients and forty control [...]texto impreso
The eye is continuously exposed to solar UV radiation and pollutants, making it prone to oxidative attacks. In fact, oxidative damage is a major cause of age-related ocular diseases including cataract, glaucoma, age-related macular degeneration [...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Crooke, Almudena ; Guzmán Aranguez, Ana María ; Pintor, Jesús | Elsevier | 2016-07-14Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substance[...]texto impreso
Andrés Guerrero, Vanessa ; Molina Martínez, Irene Teresa ; Peral Cerdá, Assumpta ; De las Heras Polo, Beatriz ; Pintor, Jesús ; Herrero Vanrell, Rocío | Association for Research in Vision and Ophthalmology (ARVO) | 2011-03Purpose.: 5-Methoxy-carbonylamino-N-acetyltryptamine (5-MCA-NAT, a melatonin receptor agonist) produces a clear intraocular pressure (IOP) reduction in New Zealand White rabbits and glaucomatous monkeys. The goal of this study was to evaluate wh[...]texto impreso
TRPV4 activation triggers the release of melatonin from human non-pigmented ciliary epithelial cells
Melatonin is a neurohormone mainly produced in the pineal gland; nevertheless, various ocular structures such as the ciliary body, lens and the retina produce it. One of the roles of melatonin in the eye is the modulation of intraocular pressure[...]texto impreso
Alkozi, Hanan Awad ; Pérez de Lara, María Jesús ; Sánchez Naves, Juan ; Pintor, Jesús | MDPI | 2017-04Melatonin is a molecule which has gained a great deal of interest in many areas of science; its synthesis was classically known to be in the pineal gland. However, many organs synthesize melatonin, such as several ocular structures. Melatonin is[...]