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Autor Pintor, Jesús |
Documentos disponibles escritos por este autor (65)
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Dominguez Godínez, Carmen Olalla ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | Mary Ann Liebert | 2018-03-01Purpose: The aim of this study was to evaluate the ability to uptake and to deliver diquafosol from commercial contact lenses (CLs) and its effect on tear secretion. Methods: For both in vitro and in vivo experiments, two commercial silicone hyd[...]texto impreso
Guzmán Aránguez, Ana Isabel ; Fonseca, Begoña ; Carracedo Rodríguez, Juan Gonzalo ; Martín Gil, Alba ; Martínez Águila, Alejandro ; Pintor, Jesús | Contact Lens Association of Ophthalmologists | 2016-09Dry eye disease affects a substantial segment of the word population with increasing frequency. It is a multifactorial disease of the ocular surface and tear film, which causes ocular discomfort, visual disturbances, and tear instability with po[...]texto impreso
Mediero Muñoz, Aránzazu ; Peral Cerdá, Assumpta ; Pintor, Jesús | The Association for Research in Vision and Ophthalmology, Inc. | 2006-10Purpose. To investigate the influence of diadenosine polyphosphates on the rate of corneal epithelial cell migration. Methods. Primary corneal epithelial cell cultures were obtained from New Zealand White rabbits. Immunocytochemical experiments [...]texto impreso
Crooke, Almudena ; Guzmán Aránguez, Ana Isabel ; Mediero Muñoz, Aránzazu ; Alarma-Estrany, Pilar ; Carracedo Rodríguez, Juan Gonzalo ; Pelaez, Teresa ; Peral Cerdá, Assumpta ; Pintor, Jesús | Taylor & Francis | 2015-01Purpose: We have investigated the effect of melatonin and its analogues on rabbit corneal epithelial wound healing. Methods: New Zealand rabbits were anaesthetised and wounds were made by placing Whatman paper discs soaked in n-heptanol on the c[...]texto impreso
Navarro Gil, Francisco Javier ; Huete Toral, Fernando ; Crooke, Almudena ; Dominguez Godínez, Carmen Olalla ; Carracedo Rodríguez, Juan Gonzalo ; Pintor, Jesús | American Society for Pharmacology and Experimental Therapeutics | 2019-10Melatonin has been shown to enhance tear secretion associated with dinucleotide diadenosine tetraphosphate. This study investigated the isolated action of melatonin and its analogs, agomelatine, N-butanoyl-2-(2-methoxy-6H-isoindolo[2,1-a]indol-1[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Martínez Águila, Alejandro ; Rodríguez Pomar, Candela ; Bodas Romero, Julia ; Sánchez Naves, Juan ; Pintor, Jesús | Springer Verlag | 2019-10-24Purpose: To evaluate the effect of a new nutritional supplement based on melatonin on the intraocular pressure (IOP) in normotensive subjects. Patients and methods: A short-term prospective study was designed. Sixty-seven normotensive subjects w[...]texto impreso
Carracedo Rodríguez, Juan Gonzalo ; Martín Gil, Ana ; Fonseca, Begoña ; Pintor, Jesús | Elsevier | 2016-08Objective: To evaluate the differences between goblet cell density (GCD) and symptomatology after one month of orthokeratology lens wear. Methods: A pilot, short-term study was conducted. Twenty-two subjects (29.7. ±. 7.0 years old) participated[...]texto impreso
Alkozi, Hanan Awad ; Sánchez Naves, Juan ; Pérez de Lara, María Jesús ; Carracedo Rodríguez, Juan Gonzalo ; Fonseca, Begoña ; Martínez Águila, Alejandro ; Pintor, Jesús | John Wiley & Sons Ltd. | 2016-09-06Purpose: To study the levels of melatonin in the aqueous humour of normotensive and hypertensive intraocular pressure (IOP) patients and to compare them to an animal model of glaucoma. Methods : A total of 37 eyes of 37 patients who underwent ca[...]texto impreso
Sight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year [...]texto impreso
Reyes Resina, Irene ; Alkozi, Hanan Awad ; Ser-Badia, Anna, del ; Sánchez Naves, Juan ; Lillo, Jaume ; Jiménez Cano, Jasmina ; Pintor, Jesús ; Navarro Brugal, Gemma ; Franco Fernández, Rafael | MDPI | 2020-01-08Background: Experiments in the late nineties showed an inverse relationship in the eye levels of melatonin and dopamine, thereby constituting an example of eye parameters that are prone to circadian variations. The underlying mechanisms are not [...]texto impreso
Pintor, Jesús ; Sánchez Nogueiro, Jesús ; Irazu, Marta ; Mediero Muñoz, Aránzazu ; Pelaez, Teresa ; Peral Cerdá, Assumpta | Springer | 2004Nucleotides present an important role in ocular physiology which has been demonstrated by recent works that indicate their involvement in many ocular processes. P2Y are important among P2 receptors since they can control tear production, corneal[...]texto impreso
Melatonin is a neurohormone synthesized in the pineal gland as well as in other organs and it plays an important role in many ocular functions, as it is synthesized in numerous eye structures. Melatonin can reduce the intraocular pressure and to[...]texto impreso
Dominguez Godínez, Carmen Olalla ; Martin-Gil, Alba ; Carracedo Rodríguez, Juan Gonzalo ; Guzmán Aranguez, Ana María ; Gonzalez-Meijome, Jose Manuel ; Pintor, Jesús | Spanish General Council of Optometrists | 2013-10Purpose To evaluate the possible use of soft contact lenses (CL) to improve the secretagogue role of diadenosine tetraphosphate (Ap4A) promoting tear secretion. Methods Two conventional hydrogel CL (Omafilcon A and Ocufilcon D) and two silico[...]texto impreso
Guzmán Aránguez, Ana Isabel ; Calvo del Bosque, Patricia ; Ropero Berzal, Inés ; Pintor, Jesús | Mary Ann Liebert | 2014-11-06Purpose: Treatment with topical eye drops for long-standing ocular diseases like allergy can induce detrimental side effects. The purpose of this study was to investigate in vitro cytotoxicity of commercially preserved and unpreserved anti-aller[...]texto impreso
Pérez de Lara, María Jesús ; Guzmán Aránguez, Ana Isabel ; Gómez Villafuertes, María Rosa ; Gualix, Javier ; Miras Portugal, María Teresa ; Pintor, Jesús | Springer | 2018-06-08The pathogenesis of glaucoma involves numerous intracellular mechanisms including the purinergic system contribution. Furthermore, the presence and release of nucleotides and dinucleotides during the glaucomatous damage and the maintenance of de[...]