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Activation of the yeast cell wall integrity MAPK pathway by zymolyase depends on protease and glucanase activities and requires the mucin-like protein Hkr1 but not Msb2

Rodríguez Peña, José Manuel ; Diez-Muñiz, Sonia ; Bermejo, Clara ; Nombela, César ; Arroyo, Javier | Elsevier | 2013-10-04

Yeast adaptation to conditions in which cell wall integrity is compromised mainly relies on the cell wall integrity (CWI) mitogen-activated protein kinase (MAPK) pathway. Zymolyase, a mixture of cell wall-digesting enzymes, triggers a peculiar s[...]

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Chromatin remodeling by the SWI/SNF complex is essential for transcription mediated by the yeast cell wall integrity MAPK pathway.

Sanz, A. Belén ; García, Raúl ; Rodríguez-Peña, José Manuel ; Diez-Muñiz, Sonia ; Nombela, César ; Peterson, Craig L. ; Arroyo, Javier | 2012-05-23

In Saccharomyces cerevisiae, the transcriptional program triggered by cell wall stress is coordinated by Slt2/Mpk1, the mitogen-activated protein kinase (MAPK) of the cell wall integrity (CWI) pathway, and is mostly mediated by the transcription[...]

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