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Ruwisch, Jannik ; Sehlmeyer, Kirsten ; Roldán López, Nuria ; García Álvarez, Begoña ; Pérez-Gil, Jesús ; Weaver, Timothy E. ; Ochs, Matthias ; Knudsen, Lars ; López-Rodríguez, Elena | American Thoracic Society | 2020-01-10Surfactant protein (SP)-C deficiency is found in samples from patients with idiopathic pulmonary fibrosis, especially in familial forms of this disease. We hypothesized that SP-C may contribute to fibrotic remodeling in aging mice and alveolar l[...]texto impreso
López-Rodríguez, Elena ; Pascual, Alicia ; Arroyo, Raquel ; Floros, Joanna ; Pérez Gil, Jesús | BIOPHYSICAL SOCIETY | 2016-08Pulmonary surfactant is a lipoprotein complex that reduces surface tension to prevent alveolar collapse and contributes to the protection of the respiratory surface from the entry of pathogens. Surfactant protein A (SP-A) is a hydrophilic glycop[...]texto impreso
López-Rodríguez, Elena ; Roldán López, Nuria ; García-Álvarez, Begoña ; Pérez-Gil, Jesús | American Society for Biochemistry and Molecular Biology | 2019-02Traditionally, thin layer chromatography (TLC) has been used for the analysis of lipids isolated from membrane complexes. Here, we describe a method based on the combination of TLC and SDS-polyacrylamide gel electrophoresis (SDS-PAGE) for the qu[...]
