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Ardura, Juan A. ; Portal Núñez, Sergio ; Lozano Borregón, Daniel ; Gutiérrez Rojas, Irene ; Sánchez Salcedo, Sandra ; López Herradón, Ana ; Mulero, Francisca ; Villanueva Penacarrillo, Maria L. ; Vallet Regí, María ; Esbrit, Pedro | Wiley | 2016-08Diabetes mellitus (DM) and aging are associated with bone fragility and increased fracture risk. Both (1-37) N- and (107-111) C-terminal parathyroid hormone-related protein (PTHrP) exhibit osteogenic properties. We here aimed to evaluate and com[...]texto impreso
Lozano Borregón, Daniel ; Sánchez Salcedo, Sandra ; Portal Núñez, Sergio ; Vila, Mercedes ; López Herradón, Ana ; Ardura, Juan A. ; Mulero, Francisca ; Gómez Barrena, Enrique ; Vallet Regí, María ; Esbrit, Pedro | Elsevier | 2014-07Biopolymer-coated nanocrystalline hydroxyapatite (HA) made as macroporous foams which are degradable and flexible are promising candidates as orthopaedic implants. The C-terminal (107-111) epitope of parathyroid hormone-related protein (PTHrP) e[...]texto impreso
Ardura, Juan A. ; Portal Núñez, Sergio ; Castelbón Calvo, Irantzu ; Martínez de Toda Cabeza, Irene ; Fuente del Rey, Mónica de la ; Esbrit, Pedro | Wiley Online Library | 2017Oxidative damage is an important contributor to the morphological and functional changes in osteoporotic bone. Aging increases the levels of reactive oxygen species (ROS) that cause oxidative stress and induce osteoblast apoptosis. ROS modify se[...]
