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Mejías, Andrés ; Díez-Hermano, Sergio ; Ganfornina, María D. ; Gutiérrez Pozo, Gabriel ; Sánchez, Diego | Public Library of Science (PLOS) | 2019-03-06The Lipocalin family is a group of homologous proteins characterized by its big array of functional capabilities. As extracellular proteins, they can bind small hydrophobic ligands through a well-conserved ?-barrel folding. Lipocalins evolutiona[...]texto impreso
Díez Hernando, Sergio ; Mejías, Andrés ; Sánchez, Diego ; Gutiérrez Pozo, Gabriel ; Ganfornina, María D. | Public Library of Sciences (PLOS) | 2020-06-19The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection,[...]texto impreso
Díez-Hernando, Sergio ; Ganfornina, María D. ; Vargas Lozano, Esteban ; Sánchez, Diego | Frontiers Media | 2020-06-04The fruit fly compound eye is a premier experimental system for modeling human neurodegenerative diseases. The disruption of the retinal geometry has been historically assessed using time-consuming and poorly reliable techniques such as histolog[...]
