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Saborido Modia, Ana ; Arroyo Sánchez, Miguel ; Feito Castellano, María José ; Navarro LLorens, Juana María | 2015Este informe corresponde a un proyecto de innovación educativa de la UCM. En la realización del proyecto, se han abierto vías para adaptar al inglés la asignatura "Laboratorio de Bioquímica y Biología Molecular I" correspondiente al segundo curs[...]texto impreso
Montes-Casado, María ; Sanvicente, Adrián ; Casarrubios Molina, Laura ; Feito Castellano, María José ; Rojo, J.M. ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portoles, Pilar ; Portolés Pérez, María Teresa | MDPI | 2020-11-05Mesoporous bioactive glass nanospheres (NanoMBGs) have high potential for clinicalapplications. However, the impact of nanoparticles on the immune system needs to be addressed. In this study, the biocompatibility of SiO2-CaO NanoMBGs was evalua[...]texto impreso
Feito Castellano, María José ; Díez-Orejas, Rosalia ; Cicuendez, Monica ; Casarrubios, Laura ; Rojo, José María ; Portolés Pérez, María Teresa | Elsevier | 2019-04-01Macrophages play a key role in nanoparticle removal and are primarily responsible for their uptake and trafficking in vivo. Due to their functional plasticity, macrophages display a spectrum of phenotypes between two extremes indentified as pro-[...]texto impreso
Navarro LLorens, Juana María ; Saborido Modia, Ana ; Arroyo Sánchez, Miguel ; Feito Castellano, María José ; Sánchez Torralba, Antonio ; Gavilanes Franco, Francisco ; Lorente Pérez, Mar ; Barderas Manchado, Rodrigo ; López Conejo, Teresa ; Ranz Valdecasa, Regina | 2017-06-02Proyecto de innovación realizado en el curso 16-17 en la asignatura del laboratorio integrado BBM1 del segundo curso del grado de Bioquimica de la UCM.texto impreso
Saborido Modia, Ana Isolina ; Arroyo Sánchez, Miguel ; Feito Castellano, María José ; Olmeda Lozano, Bárbara ; Mata Riesco, María Isabel de la ; Garrido Bueno, José Luis ; Nieto Bueno, José Luis ; Amigot Sánchez, Rafael ; Blanco Arribas, Elena ; Cueto Remacha, Mateo ; Guerra Espinosa, Claudia ; Rodríguez Solana, Patricia | 2020-06-10Con objeto de fomentar el aprendizaje activo en el laboratorio de Bioquímica BBM1, se diseñaron, emplearon y evaluaron una serie de actividades y herramientas: (i) test pre-laboratorio, realizados mediante la aplicación Socrative; (ii) herramien[...]texto impreso
Matesanz Sancho, María Concepción ; Feito Castellano, María José ; Oñaderra Sánchez, Mercedes ; Ramirez Santillán, Cecilia ; Casa, Carmen da ; Arcos Navarrete, Daniel ; Vallet Regí, María ; Rojo, José María ; Portolés Pérez, María Teresa | Elsevier | 2014-02-15Hypothesis: Synthetic hydroxyapatite (HA) and Si substituted hydroxyapatite (SiHA) are calcium phosphate ceramics currently used in the field of dentistry and orthopaedic surgery. The preparation of both biomaterials as polycrystalline solid pie[...]texto impreso
Torres-Rodriguez, Carolina ; Portolés Pérez, M. T. ; Matesanz Sancho, María Concepción ; Linares, Javier ; Feito Castellano, María José ; Izquierdo-Barba, Isabel ; Esbrit, Pedro ; Vallet Regí, María | Elsevier | 2016-01-01Hypothesis: Dental bleaching with H2O2 is a common daily practice in dentistry to correct discoloration of anterior teeth. The aim of this study has been to determine whether this treatment of human teeth affects growth, differentiation and acti[...]texto impreso
Feito Castellano, María José ; Serrano, M. C. ; Oñaderra Sánchez, Mercedes ; Matesanz Sancho, María Concepción ; Sánchez Salcedo, Sandra ; Arcos Navarrete, Daniel ; Vallet Regí, María ; Portolés Pérez, María Teresa | Royal Society of Chemistry | 2016-09-21Vascular endothelial growth factor (VEGF) plays an essential role in angiogenesis and vascular homeostasis. Endothelial progenitor cells (EPCs) are primitive bone marrow cells participating in neovascularization and revascularization processes, [...]texto impreso
Gómez-Cerezo, Natividad ; Casarrubios, L. ; Morales, I. ; Feito Castellano, María José ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | Elsevier | 2018-10-15A mesoporous bioactive glass (MBG) of molar composition 75SiO2-20CaO-5P2O5 (MBG-75S) has been synthetized as a potential bioceramic for bone regeneration purposes. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), nitroge[...]texto impreso
Díez Orejas, Rosalía ; Casarrubios, Laura ; Feito Castellano, María José ; Rojo, J.M. ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | Elsevier | 2021-02-15The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a[...]texto impreso
Sánchez Torralba, Antonio ; Feito Castellano, María José ; Arroyo Sánchez, Miguel ; Saborido Modia, Ana ; Navarro LLorens, Juana María | 2016Este proyecto persigue fomentar la adquisición de conocimientos y habilidades en el laboratorio de Bioquímica combinando estrategias multimedia con el aprendizaje cooperativo centrado en el alumno y haciendo hincapié en la adaptación al inglés d[...]texto impreso
Maycas, Marta ; Portolés Pérez, María Teresa ; Matesanz Sancho, María Concepción ; Buendía, Irene ; Linares, Javier ; Feito Castellano, María José ; Arcos Navarrete, Daniel ; Vallet Regí, María ; Plotkin, Lilian I. ; Esbrit, Pedro ; Gortázar, Arancha R. | Wiley | 2017-12Diabetes mellitus (DM) induces bone deterioration, while mechanical stimulation promotes osteocyte-driven bone formation. We aimed to evaluate the interaction of acute exposure (24 h) to high glucose (HG) with both the pro-survival effect confer[...]texto impreso
Feito Castellano, María José ; Vila, Mercedes ; Matesanz Sancho, Mª Concepción ; Linares, J. ; Gonçalves, G. ; Marques, P.A.A.P. ; Vallet Regí, María ; Rojo, J.M. ; Portolés Pérez, Teresa | Elsevier | 2014Graphene oxide (GO) has attracted the scientific community attention due to its novel properties and wide range of potential applications including hyperthermia cancer therapy. However, little is known about the GO effects on the immune function[...]texto impreso
Casarrubios, Laura ; Gómez-Cerezo, Natividad ; Feito Castellano, María José ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | Elsevier | 2018-12-01Mesoporous nanospheres in the system SiO2-CaO (NanoMBGs) with a hollow core surrounded by a radial arrangement of mesopores were characterized, labeled with FITC (FITC-NanoMBGs) and loaded with ipriflavone (NanoMBG-IPs) in order to evaluate thei[...]texto impreso
Linares, Javier ; Matesanz Sancho, María Concepción ; Feito Castellano, María José ; Salavagione, Horacio Javier ; Martínez, Gerardo ; Gómez Fatou, Marian | Elsevier | 2016-02The differences in the response of human Saos-2 osteoblasts to nanocomposites of poly(vinyl alcohol) (PVA) and 1.5 wt.% graphene oxide (GO) prepared by covalent linking (PVA/GO-c) and simple blending (PVA/GO-m) have been evaluated through differ[...]
