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Documentos disponibles de esta editorial (380)
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Casado Hernández, Israel ; Becerro de Bengoa Vallejo, Ricardo ; Losa-Iglesias, Marta Elena ; López-López, Daniel ; Rodríguez Sanz, David ; Martínez Jiménez, Eva María ; Calvo-Lobo, César | MDPI | 2019-05-15Customized foot insoles (CFI) have been recognized to reduce the prevalence of foot disorders in sport. The aim of this study was to evaluate the effect of four types of CFI on the activity patterns of the lower limb muscles (LLM) in healthy peo[...]![]()
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De la Torre, Paz ; Paris, J. L. ; Fernández de la Torre, Miguel ; Vallet Regí, María ; Flores, Ana I. | MDPI | 2021-02-10Combination therapies constitute a powerful tool for cancer treatment. By combining drugs with different mechanisms of action, the limitations of each individual agent can be overcome, while increasing therapeutic benefit. Here, we propose emplo[...]![]()
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Chacón Sombría, Jesús ; Besada Portas, Eva ; Carazo Barbero, Gonzalo ; López Orozco, José Antonio | MDPI | 2021-02Easy JavaScript Simulations (EJsS) is an open-source tool that allows teachers with limited programming experience to straightforwardly bundle an interactive computer science or engineer simulation in an HTML+ JavaScript webpage. Its prominent p[...]![]()
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Alfaro Sánchez, David ; Rodríguez Sosa, Mariano R. ; Zapata González, Agustín Gregorio | MDPI | 2020-01-22Mesenchymal stromal/stem cells (MSCs) have emerged as important therapeutic agents, owing to their easy isolation and culture, and their remarkable immunomodulatory and anti-inflammatory properties. However, MSCs constitute a heterogeneous cell [...]![]()
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Rodríguez Sousa, Antonio Alberto ; Barandica Fernández, Jesús María ; Rescia Perazzo, Alejandro Javier | MDPI | 2019-11-21Spain is the world’s leading producer of olive oil, with the largest number of olive agro-systems in the Andalusia region. However, rural migration, low profitability, and biophysical limitations to production have compromised their sustainabili[...]![]()
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Sánchez de Miguel, Alejandro ; Bará, Salvador ; Aubé, Martin ; Cardiel López, Nicolás | MDPI | 2019-04Night-time lights interact with human physiology through different pathways starting at the retinal layers of the eye; from the signals provided by the rods; the S-, L- and M-cones; and the intrinsically photosensitive retinal ganglion cells (ip[...]![]()
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Puerto Parejo, Luis ; Aliaga Vera, Ignacio ; Canal Macias, María ; Leal Hernandez, Olga ; Roncero Martín, Raul ; Rico Martín, Sergio ; Moran, Jose | MDPI | 2017Background: Heavy metals, such as lead, cadmium, and mercury, are absorbed through contaminated food sources and water. Few studies have investigated the extent to which dietary heavy metals are associated with low bone mineral density. Aims: W[...]![]()
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Rodríguez Sousa, Antonio Alberto ; Parra López, Carlos ; Sayadi-Gmada, Samar ; Barandica Fernández, Jesús María ; Rescia Perazzo, Alejandro Javier | MDPI | 2020-10-01Olive groves are representative of the landscape and culture of Spain. They occupy 2.5 M ha. (1.5 M ha in Andalusia) and are characterised by their multifunctionality. In recent years, socio-economic and environmental factors (i.e., erosion) hav[...]![]()
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Martos Villa, Rubén ; Mata, M. Pilar ; Williams, Lynda B. ; Nieto, Fernando ; Arroyo Rey, Xabier ; Saínz-Díaz, C.I. | MDPI | 2020Clay dehydration at great depth generates fluids and overpressures in organic-rich sediments that can release isotopically light boron from mature organic matter, producing 10B-rich fluids. The B can be incorporated into the tetrahedral sites of[...]![]()
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Two stratigraphic sections of carbonate sediments with significant thickness differences and without appreciable tectonic deformation were studied near the trough and on a threshold zone at the Álava Trough. Such characteristics make them approp[...]![]()
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Barquero, Nuria ; Gomez Lucia, Esperanza ; Arjona, Alvaro ; Toural, Cristina ; Heras, Alfonso las ; Fernández Garayzábal, José F ; Doménech, Ana | MDPI | 2013-10-22The diagnosis of Small Ruminant Lentivirus (SRLV) is based on clinical signs, pathological lesions and laboratory testing. No standard reference test for the diagnosis of maedi visna has been validated up to the present, and it is puzzling that [...]![]()
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Ariza García, Rocío ; Sotillo Buzarra, Belén ; Pavón Martínez, Fernando ; Urbieta Quiroga, Ana Irene ; Fernández Sánchez, Paloma | MDPI | 2020-12-01The investigated materials have great potential for integrated optoelectronic devices. The possibility to integrate them into the same material as optical resonator and light guide opens the door to the fabrication of highly compact devices. The[...]![]()
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Rodríguez Sousa, Antonio Alberto ; Barandica Fernández, Jesús María ; Aguilera, Pedro A. ; Rescia Perazzo, Alejandro Javier | MDPI | 2020-10-29Olive groves form characteristic Mediterranean socio-ecological landscapes, occupying more than 5 M ha; 2.5 M ha in Spain. In recent decades, traditional extensive management of olive groves has shifted to an intensive regime, with some cases of[...]![]()
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Experimental Study for Improving the Repair of Magnesium–Aluminium Hybrid Parts by Turning Processes
Rubio, Eva ; Villeta López, María del Carmen ; Valencia Delfa, José Luis ; Sáenz de Pipaón, José | MDPI | 2018One of the lightest metallic materials used in the aeronautics, aerospace, and automotive industries, among others, is magnesium, due to its excellent weight/strength ratio. Most parts used in these industries need to be made of materials that a[...]![]()
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Urban centres in Europe have been recently affected by touristification processes which endanger their sustainable development. In this context, education in urban sustainability is gaining great importance at all stages of education. It has bee[...]![]()
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Reyes Resina, Irene ; Alkozi, Hanan Awad ; Ser-Badia, Anna, del ; Sánchez Naves, Juan ; Lillo, Jaume ; Jiménez Cano, Jasmina ; Pintor, Jesús ; Navarro Brugal, Gemma ; Franco Fernández, Rafael | MDPI | 2020-01-08Background: Experiments in the late nineties showed an inverse relationship in the eye levels of melatonin and dopamine, thereby constituting an example of eye parameters that are prone to circadian variations. The underlying mechanisms are not [...]![]()
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Benito, Gerardo ; Sánchez Moya, Yolanda ; Medialdea, Alicia ; Barriendos, Mariano ; Calle, Mikel ; Rico, Mayte ; Sopeña, Alfonso ; Machado, María J. | MDPI | 2020Climate change implies changes in the frequency and magnitude of flood events. The influence of climate variability on flooding was evaluated by an analysis of sedimentary (palaeofloods) and documentary archives. A 500-year palaeoflood record at[...]![]()
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Billings, Joshua-D. ; Joseph-Davey, Dvora-L. ; Konda, Kelika-A. ; Bristow, Claire-C. ; Chow, Jeremy ; Klausner, Jeffrey-D. ; Caceres, Carlos-F. | MDPI | 2019-02-06T14:51:17ZThe aim of the study was to identify factors associated with undiagnosed human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) and male-to-female transgender women in Lima, Peru.We analyzed characteristics of 378 MS[...]![]()
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López Quintás, Ignacio ; Rebollar, Esther ; Ávila Brande, David ; Izquierdo, Jesús G. ; Díaz-Guerra Viejo, Carlos ; Urbieta Quiroga, Ana Irene ; Castillejo, Marta ; Nalda, Rebeca de ; Martín, Margarita | MDPI | 2020-11Nanostructured thin films of Co-doped zinc sulfide were synthesized through femtosecond pulsed laser deposition. The scheme involved ablation of physically mixed Co and ZnS with pairs of ultrashort pulses separated in time in the 0-300 ps range.[...]![]()
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Canullo, Luigi ; Genova, Tullio ; Gross Trujillo, Esperanza ; Pradíes Ramiro, Guillermo ; Petrillo, Sara ; Muzzi, Maurizio ; Carossa, Stefano ; Mussano, Federico | MDPI | 2020Background: Attaining an effective mucosal attachment to the transmucosal part of the implant could protect the peri-implant bone. Aim: To evaluate if chair side surface treatments (plasma of Argon and ultraviolet light) may affect fibroblast ad[...]![]()
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Humans and fire form a coupled and co-evolving natural-human system in Mediterranean-climate ecosystems. In this context, recent trends in landscape change, such as urban sprawl or the abandoning of agricultural and forest land management in lin[...]![]()
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Garrote Revilla, Julio ; Díez Herrero, Andrés ; Bodoque del Pozo, José María ; Perucha, M.A. ; Mayer, Pablo L. | MDPI | 2017-12-31Las Angustias River is an ungauged stream in the Caldera de Taburiente National Park (Spain), where frequent intense flash-flood events occur. The aim of this research is to analyze the flood hazard at the Playa de Taburiente. Based on the limit[...]![]()
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Studies looking at flood risk analysis and assessment (FRA) reviews are not customary, and they usually approach to methodological and spatial scale issues, uncertainty, mapping or economic damage topics. However, most of these reviews provide a[...]![]()
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Gomez-Lucia, Esperanza ; Collado Alcalá, Victorio Manuel ; Miró, Guadalupe ; Martín, Sonsoles ; Benítez Rico, Laura ; Doménech, Ana | MDPI | 2019-09-11Specific treatments for the long-life infections by feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are either toxic, expensive or not too effective. Interferon ? (IFN-?) is an immunomodulatory molecule which has been shown [...]![]()
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Perez-Leon, Silvana ; Pesantes, M. Amalia ; Aya Pastrana, Nathaly ; Raman, Shivani ; Miranda, Jaime ; Suggs, L. Suzanne | MDPI | 2018-11-30T03:10:46ZPeru is undergoing a nutrition transition and, at the country level, it faces a double burden of disease where several different conditions require dietary changes to maintain a healthy life and prevent complications. Through semistructured inte[...]![]()
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López-López, Daniel ; Vilar-Fernández, Juan ; Barros-García, Gonzalo ; Losa-Iglesias, Marta ; Palomo-López, Patricia ; Becerro de Bengoa Vallejo, Ricardo ; Calvo-Lobo, César | MDPI | 2018-07-23Background: Variations in the foot structure related with the high or low arch are identified common lower limb conditions, and it is supposed to be the effect on the quality of life (QoL) associated to foot health in adults. Here we aimed to de[...]![]()
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Rodríguez Temiño, Ignacio ; Yáñez Vega, Ana ; Jorge Villar, Susana ; Reyes Mateo, Álvaro ; Rufino Rus, Javier ; Salas Álvarez, Jesús ; Lavín Berdonces, Ana | MDPI | 2018For most of its history, archaeology has too often taken an indulgent attitude toward looting and antiquities trafficking. The primary response to these dangers has been to publish the main findings made outside of academia. As a result of this [...]![]()
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Laqbaqbi, Mourad ; Sanmartino Rodríguez, Julio Antonio ; Khayet Souhaimi, Mohamed ; García Payo, María del Carmen ; Chaouch, Mehdi | MDPI | 2017-05Various membrane separation processes are being used for seawater desalination and treatment of wastewaters in order to deal with the worldwide water shortage problem. Different types of membranes of distinct morphologies, structures and physico[...]![]()
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Floods, at present, may constitute the natural phenomenon with the greatest impact on the deterioration of cultural heritage, which is the reason why the study of flood risk becomes essential in any attempt to manage cultural heritage (archaeolo[...]![]()
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Rivera de la Torre, Esperanza ; Palacios Ortega, Juan ; Slotte, J. Peter ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; García Linares, Sara | MDPI | 2020-11Venoms constitute complex mixtures of many different molecules arising from evolution in processes driven by continuous prey–predator interactions. One of the most common compounds in these venomous cocktails are pore-forming proteins, a family [...]![]()
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Gravity can be formulated as a gauge theory by combining symmetry principles and geometrical methods in a consistent mathematical framework. The gauge approach to gravity leads directly to non-Euclidean, post-Riemannian spacetime geometries, pro[...]![]()
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Olombrada, Miriam ; Lázaro Gorines, Rodrigo ; López Rodríguez, Juan C. ; Martínez del Pozo, Álvaro ; Oñaderra, Mercedes ; Maestro López, Moisés ; Lacadena, Javier ; Gavilanes, José G. ; García Ortega, Lucía | MDPI | 2017Fungi establish a complex network of biological interactions with other organisms in nature. In many cases, these involve the production of toxins for survival or colonization purposes. Among these toxins, ribotoxins stand out as promising candi[...]![]()
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Delgado Piña, María Isabel ; Rodríguez Ruiz, Óscar ; Rodríguez Duarte, Antonio ; Sastre Castillo, Miguel Ángel | MDPI | 2020The study of the gender composition of top management and its impact for organizations has received increasing attention during recent decades. Despite this, findings have been conflicting and few consistent conclusions have been reached. This p[...]![]()
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The notion of the orbifold Euler characteristic came from physics at the end of the 1980s. Coincidence (up to sign) of the orbifold Euler characteristics is a necessary condition for crepant resolutions of orbifolds to be mirror symmetric. There[...]![]()
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García-Rivas, Javier ; Suárez, Mercedes ; Torres, Trinidad ; Sánchez-Palencia, Yolanda ; García Romero, Emilia ; Ortiz, J.E. | MDPI | 2018The Tajo Basin is one of the richest in Mg-clays known around the world. Mg-bentonites, kwon as pink clays and green clays, alter in the Intermediate Unit of the Miocene sediments. In this work, a new approach to the genesis of these bentonites [...]![]()
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Escayo, Joaquin ; Fernández, José ; Prieto, Juan F. ; Camacho, Antonio G. ; Palano, Mimmo ; Aparicio, Alfredo ; Rodríguez Velasco, Gema ; Ancochea Soto, Eumenio | MDPI | 2020-08-10La Palma is one of the youngest of the Canary Islands, and historically the most active. The recent activity and unrest in the archipelago, the moderate seismicity observed in 2017 and 2018 and the possibility of catastrophic landslides related [...]![]()
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Perales, María ; Valenzuela, Pedro L. ; Barakat, Ruben ; Cordero Rodríguez, Yaiza ; Peláez, Mireia ; López, Carmen ; Ruilope, Luis M. ; Santos-Lozano, Alejandro ; Lucia, Alejandro | MDPI | 2020We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology ([...]![]()
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Avila-Burgos, Leticia ; Montañez-Hernández, Julio César ; Cahuana-Hurtado, Lucero ; Villalobos, Aremis ; Hernandez-Pena, Patricia ; Heredia-Pi, Ileana | MDPI | 2020-07-14T00:00:54ZThe purpose of this study was to assess whether government policies to expand the coverage of maternal health and family planning (MHFP) services were benefiting the adolescents in need. To this end, we estimated government MHFP expenditure for [...]![]()
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Vera González, Vicente ; Moran, Jose ; Barros, Patricia ; Canal-Macias, Maria ; Guerrero-Bonmatty, Rafael ; Costa-Fernandez, Carmen ; Lavado-Garcia, Jesus ; Roncero-Martin, Raul ; Pedrera-Zamorano, Juan | MDPI | 2015We aimed to investigate and compare the effects of chronic antiepileptic therapy on bone health in pediatric patients using quantitative ultrasound of the phalanges (QUS) and controlling for potential confounding factors, particularly nutrient i[...]![]()
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The entropy of Boltzmann-Gibbs, as proved by Shannon and Khinchin, is based on four axioms, where the fourth one concerns additivity. The group theoretic entropies make use of formal group theory to replace this axiom with a more general composa[...]![]()
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Sequeira, Catarina Romão ; Rego, Francisco ; Montiel Molina, Cristina ; Morgan, Penelope | MDPI | 2019Wildfires in the Iberian Peninsula were large and frequent in the second half of the 20th century. Land use and land cover (LULC) also changed greatly. Our aim was to understand the relationship between LULC and fire in the western and eastern e[...]![]()
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Montiel Molina, Cristina ; Vilar, Lara ; Sequeira, Catarina Romão ; Karlsson, Oskar ; Galiana-Martín, Luis ; Madrazo-García de Lomana, Gonzalo ; Palacios Estremera, Mª Teresa | MDPI | 2019Fire is one of the main disturbance factors shaping the landscape, and landscape is a key driver of fire behavior. Considering the role played by land use and land cover (LULC) changes as the main driver of landscape dynamics, the aim of this st[...]![]()
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Aparicio García, Marta Evelia ; Díaz Ramiro, Eva María ; Rubio Valdehita, Susana ; López Núñez, María Inmaculada ; García-Nieto, Isidro | MDPI | 2018Young transgender and non-binary individuals (TNBI) are exposed to situations of discrimination and have a greater risk of violence. The purpose of this study is to analyze which protective, violence and health and well-being factors have more i[...]![]()
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Sánchez Gómez, Rubén ; Becerro de Bengoa Vallejo, Ricardo ; Losa-Iglesias, Marta Elena ; Calvo-Lobo, César ; Romero-Morales, Carlos ; Martínez Jiménez, Eva María ; Palomo-López, Patricia ; López-López, Daniel | MDPI | 2019-03-16Hallux abductus valgus (HAV) is a forefoot condition produced by extrinsic and intrinsic factors. Shoes with a high heel height and a typical narrow tip toe box can induce deviations in both the proximal phalanx of the hallux (PPH) and the first[...]![]()
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High-dimensional data and high-dimensional representations of reality are inherent features of modern Artificial Intelligence systems and applications of machine learning. The well-known phenomenon of the “curse of dimensionality” states: many p[...]![]()
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Morales Casero, Irene ; Hernando Grande, Antonio ; Presa Muñoz del Toro, Patricia de la ; Costo Cámara, Rocío ; Mille, Nicolas ; Bezerra Da Silva, Gustavo ; Carrey, Julian | MDPI | 2018-12In order to understand the properties involved in the heating performance of magnetic nanoparticles during hyperthermia treatments, a systematic study of different gamma-Fe_2O_3 and Fe_3O_4 nanoparticles has been done. High-frequency hysteresis [...]![]()
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Marino, Egidio ; González, Francisco Javier ; Lunar Hernández, Rosario ; Reyes, Jesús ; Medialdea, Teresa ; Castillo Carrión, Mercedes ; Bellido, Eva ; Somoza Losada, Luis | MDPI | 2018-07-02Two Fe–Mn crusts among 35 samples, from six seamounts in the Canary Island Seamount Province, were selected as representatives of the endpoint members of two distinct types of genetic processes, i.e., mixed diagenetic/hydrogenetic and purely hyd[...]![]()
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Sánchez Salcedo, Sandra ; Malavasi, Gianluca ; Salinas Sánchez, Antonio J. ; Lusvardi, Gigliola ; Rigamonti, Luca ; Menabue, Ledi ; Vallet Regí, María | MDPI | 2018-03-02Beneficial effects in bone cell growth and antibacterial action are currently attributed to Ga3+ ions. Thus, they can be used to upgrade mesoporous bioactive glasses (MBGs), investigated for tissue engineering, whenever they released therapeutic[...]![]()
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Bizhani, Hasti ; Katbab, Ali Asghar ; López Hernández, Emil ; Miranda Pantoja, José Miguel ; Verdejo, Raquel | MDPI | 2020-04The need for electromagnetic interference (EMI) shields has risen over the years as the result of our digitally and highly connected lifestyle. This work reports on the development of one such shield based on vulcanized rubber foams. Nanocomposi[...]![]()
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González-Nieto, Daniel ; Fernández-García, Laura ; Pérez-Rigueiro, José ; Guinea, Gustavo ; Panetsos, Fivos | MDPI | 2018The use of advanced biomaterials as a structural and functional support for stem cells-based therapeutic implants has boosted the development of tissue engineering applications in multiple clinical fields. In relation to neurological disorders, [...]![]()
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Marino, Egidio ; González, Francisco Javier ; Kühn, Thomas ; Madureira, Pedro ; Wegorzewski, Anna V. ; Mirao, Jose ; Medialdea, Teresa ; Oeser, Martin ; Miguel, Catarina ; Reyes Andrés, Jesús ; Somoza Losada, Luis ; Lunar Hernández, Rosario | MDPI | 2019Four pure hydrogenetic, mixed hydrogenetic-diagenetic and hydrogenetic-hydrothermal Fe-Mn Crusts from the Canary Islands Seamount Province have been studied by Micro X-Ray Diffraction, Raman and Fourier-transform infrared spectroscopy together w[...]![]()
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Alique, Matilde ; Sánchez-López, E. ; Bodega, Guillermo ; Giannarelli, Chiara ; Carracedo, Julia ; Ramírez, Rafael | MDPI | 2020-01-13Aging is one of the hottest topics in biomedical research. Advances in research and medicine have helped to preserve human health, leading to an extension of life expectancy. However, the extension of life is an irreversible process that is acco[...]![]()
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Figueroa-Ildefonso, Erick ; Bademci, Guney ; Rajabli, Farid ; Cornejo-Olivas, Mario ; Villanueva, Ruy Diego Chacon ; Badillo-Carrillo, Rodolfo ; Inca-Martinez, Miguel ; Neyra, Karina Milla ; Sineni, Claire ; Tekin, Mustafa | MDPI | 2019-08-08T15:23:45ZHearing loss (HL) is a common sensory disorder affecting over 5% of the global population. The etiology underlying HL includes congenital and acquired causes; genetic factors are the main cause in over 50% of congenital cases. Pathogenic varian[...]![]()
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Figueroa-Ildefonso, Erick ; Bademci, Guney ; Rajabli, Farid ; Cornejo-Olivas, Mario ; Villanueva, Ruy Diego Chacon ; Badillo-Carrillo, Rodolfo ; Inca-Martinez, Miguel ; Neyra, Karina Milla ; Sineni, Claire ; Tekin, Mustafa | MDPI | 2019-12-06T20:57:42Z: Hearing loss (HL) is a common sensory disorder affecting over 5% of the global population. The etiology underlying HL includes congenital and acquired causes; genetic factors are the main cause in over 50% of congenital cases. Pathogenic vari[...]![]()
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Visitor data is essential for decision-making, policy formulation, and monitoring of protected areas. In this context, the data on the temporal distribution of visitors is essential to characterize influx and seasonality, and even to measure the[...]![]()
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Imaging Thermal Anomalies in Hot Dry Rock Geothermal Systems from Near-Surface Geophysical Modelling
Gómez-Ortiz, David ; Blanco-Montenegro, Isabel ; Arnoso, José ; Martín-Crespo, Tomás ; Solla, Mercedes ; Montesinos, F. G. ; Velez, Emilio ; Sánchez, Nieves | MDPI | 2019Convective hydrothermal systems have been extensively studied using electrical and electromagnetic methods given the strong correlation between low conductivity anomalies associated with hydrothermal brines and high temperature areas. However, s[...]![]()
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López-López, Daniel ; Painceira-Villar, Roi ; García-Paz, Vanesa ; Becerro de Bengoa Vallejo, Ricardo ; Losa-Iglesias, Marta Elena ; Rodríguez Sanz, David ; Calvo-Lobo, César | MDPI | 2019-05-08Background: Asthma may be considered as a non-communicable condition associated with higher bronchial responsiveness that may impair quality of life (QoL). Purpose: The research aim was to compare scores of depression, as well as general and foo[...]![]()
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Garrote Revilla, Julio ; Díez-Herrero, Andrés ; Génova, Mar ; Bodoque del Pozo, José María | MDPI | 2018-08-10Flash floods represent one of the more usual natural hazards in mountain basins, and, combined with the lack of reliable flow data and the recreational use of the drainage basin by tourists and hikers, there is a significant risk of catastrophe.[...]![]()
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Bazta, Otman ; Urbieta Quiroga, Ana Irene ; Trasobares, Susana ; Piqueras de Noriega, Javier ; Fernández Sánchez, Paloma ; Addou, Mohammed ; Calvino, Jose Juan ; Hungría, Ana Belén | MDPI | 2020-05Pure and Ce-modified ZnO nanosheet-like polycrystalline samples were successfully synthesized by a simple and fast microwave-based process and tested as photocatalytic materials in environmental remediation processes. In an attempt to clarify th[...]![]()
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Herráez-Galindo, Cristina ; Rizo-Gorrita, María ; Luna-Oliva, Irene ; Serrera-Figallo, María-Ángeles ; Castillo Oyagüe, Raquel ; Torres-Lagares, Daniel | MDPI | 2019Polymethyl methacrylate (PMMA) and lithium disilicate are widely used materials in the dental field. PMMA is mainly used for the manufacture of removable prostheses; however, with the incorporation of CAD-CAM technology, new applications have be[...]![]()
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Ruiz-de-la-Herrán, Javier ; Tomé-Amat, Jaime ; Lázaro Gorines, Rodrigo ; Gavilanes, José G. ; Lacadena, Javier | MDPI | 2019-10-12Immunotoxins are chimeric molecules that combine the specificity of an antibody to recognize and bind tumor antigens with the potency of the enzymatic activity of a toxin, thus, promoting the death of target cells. Among them, RNases-based immun[...]![]()
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Vida, Carmen ; Carracedo Añón, Julia ; Sequera, Patricia de ; Bodega, Guillermo ; Pérez, Rafael ; Alique, Matilde ; Ramírez, Rafael | MDPI | 2020-04-15Oxidative stress is exacerbated in hemodialysis patients by several factors, including the uremic environment and the use of dialysis fluids (DFs). Since magnesium (Mg) plays a key role in modulating immune function and in reducing oxidative str[...]![]()
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Martínez Águila, Alejandro ; Martín Gil, Alba ; Carpena Torres, Carlos ; Pastrana, Cristina ; Carracedo Rodríguez, Juan Gonzalo | MDPI | 2021-02-24Circadian rhythm and the molecules involved in it, such as melanopsin and melatonin, play an important role in the eye to regulate the homeostasis and even to treat some ocular conditions. As a result, many ocular pathologies like dry eye, corne[...]![]()
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Casado-Hernández, Israel ; Becerro de Bengoa Vallejo, Ricardo ; Losa-Iglesias, Marta Elena ; Martínez-Jiménez, Eva María ; López-López, Daniel ; Mazoteras Pardo, Victoria ; Romero-Morales, Carlos ; Calvo Lobo, César | MDPI | 2020-03-11Nowadays, the use of insoles in sport practice have been recognized to decrease the foot and lower limb injury patterns. The aim of this study was to analyse the effect of four types of hardness insoles (HI) in the activity patterns of the hip a[...]![]()
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Vicente, Fátima ; Sanchiz Giraldo, África ; Rodríguez-Pérez, Rosa ; Pedrosa, María ; Quirce, Santiago ; Haddad, Joseph ; Besombes, Colette ; Linacero de la Fuente, Rosario ; Allaf, Karim ; Cuadrado Hoyos, Carmen | MDPI | 2020-04-10Pistachio and cashew contain allergenic proteins, which causes them to be removed from the diet of allergic people. Previous studies have demonstrated that food processing (thermal and non-thermal) can produce structural and/or conformational ch[...]![]()
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Mesoporous silica nanoparticles have been broadly applied as drug delivery systems 14 owing to their exquisite features, such as excellent textural properties or biocompatibility. However, 15 there are various biological barriers that prevent th[...]![]()
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At the European Union (EU) level, innovation matter is acknowledged as crucial for progress and sustainability. Related policy action is materialized through Horizon Europe, the 9th Framework Program (FP) for research and development (R&D). The [...]![]()
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Garcia-Ceca Hernández, Javier ; Montero Herradón, Sara ; Zapata González, Agustín | MDPI | 2020-10-02Intimate interactions between thymic epithelial cells (TECs) and thymocytes (T) have been repeatedly reported as essential for performing intrathymic T-cell education. Nevertheless, it has been described that animals exhibiting defects in these [...]![]()
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Jiménez, Felipe ; Naranjo, José ; Serradilla, Francisco ; Pérez Moreno, Elisa ; Hernández Lloreda, María ; Ruiz Gallego-Largo, Trinidad ; Anaya, José ; Díaz, Alberto | MDPI | 2016Inappropriate speed is a relevant concurrent factor in many traffic accidents. Moreover, in recent years, traffic accidents numbers in Spain have fallen sharply, but this reduction has not been so significant on single carriageway roads. These i[...]![]()
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Casarrubios, Laura ; Gomez Cerezo, Natividad ; Feito Castellano, María José ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | MDPI | 2020-12-21The incorporation and effects of hollow mesoporous nanospheres in the systemSiO2–CaO (nanoMBGs) containing ipriflavone (IP), a synthetic isoflavone that prevents osteoporosis, were evaluated. Due to their superior porosity and capability to host[...]![]()
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Saiz Galdós, Jesús ; Pung, Meredith A. ; Wilson, Kathleen L. ; Pruitt, Christopher ; Rutledge, Thomas ; Redwine, Laura ; Taub, Pam ; Greenberg, Barry H. ; Mills, Paul J. | MDPI | 2020-05-08In the United States, heart failure (HF) affects approximately 6.5 million adults. While studies show that individuals with HF often suffer from adverse symptoms such as depression and anxiety, studies also show that these symptoms can be at lea[...]![]()
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Issii, Thais Martins ; Pereira-Silva, Erico Fernando Lopes ; López de Pablo, Carlos Tomás ; Santos, Rozely Ferreira dos ; Hardt, Elisa | MDPI | 2020-11-18Landscape connectivity can be assessed based on the physical connection (structural connectivity) or the maintenance of flow among habitats depending on the species (functional connectivity). The lack of empirical data on the dispersal capacity [...]![]()
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Aguado Aguilar, Luis ; Parkington, Karisa ; Dieguez-Risco, Teresa ; Hinojosa Poveda, José A. ; Itier, Roxane | MDPI | 2019Faces showing expressions of happiness or anger were presented together with sentences that described happiness-inducing or anger-inducing situations. Two main variables were manipulated: (i) congruency between contexts and expressions (congruen[...]![]()
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Palomo-López, Patricia ; Becerro de Bengoa Vallejo, Ricardo ; Losa-Iglesias, Marta Elena ; López-López, Daniel ; Rodríguez Sanz, David ; Romero-Morales, Carlos ; Calvo Lobo, César ; Mazoteras Pardo, Victoria | MDPI | 2020-01-18Background: Hallux valgus (HV) has been previously associated with psychological disorders. Thus, the purposes of this study were to associate kinesiophobia and pain intensity with HV deformity degrees, as well as predict kinesiophobia and pain [...]![]()
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Lobov, Sergey ; Krilova, Nadia ; Kastalskiy, Innokentiy ; Kazantsev, Victor ; Makarov, Valeri A. | MDPI | 2018-04-06Recent advances in recording and real-time analysis of surface electromyographic signals (sEMG) have fostered the use of sEMG human–machine interfaces for controlling personal computers, prostheses of upper limbs, and exoskeletons among others. [...]![]()
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The application of a methodology based on S.C. Dik’s Functionalist Grammar linguistic principles, which is addressed to the teaching of Latin to secondary students, has resulted in a quantitative improvement in students’ acquisition process of k[...]![]()
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The properties of one-dimensional photonic quasicrystals ultimately rely on their nontrivial long-range order, a hallmark that can be quantified in many ways depending on the specific aspects to be studied. Here, we assess the quasicrystal struc[...]![]()
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Rodríguez-Cielos, Ricardo ; Galán-García, José ; Padilla-Domínguez, Yolanda ; Rodríguez-Cielos, Pedro ; Bello Patricio, Ana Belén ; López-Medina, José | MDPI | 2017There are currently several new technologies being used to generate digital elevation models that do not use photogrammetric techniques. For example, LiDAR (Laser Imaging Detection and Ranging) and RADAR (RAdio Detection And Ranging) can generat[...]![]()
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Castillo Eguskitza, Nekane ; Schmitz, María F. ; Onaindia, Miren ; Rescia Perazzo, Alejandro Javier | MDPI | 2019-05-31The search for a balance between nature conservation and sustainable development remains a scientific and spatial planning challenge. In social-ecological systems based on traditional rural activities and associated with protected areas, this ba[...]![]()
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Cañadas Benito, Olga ; Olmeda Lozano, Bárbara ; Alonso Eugenio, Alejandro ; Pérez-Gil, Jesús | MDPI | 2020-05-25Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and secreted into the airspaces, where it coats and protects the large respiratory air–liquid interface. Surfactant, assembled as a complex network of membran[...]![]()
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While most research on electronic commerce has focused on customer behaviour according to websites’ functional tasks, consumers are influenced by many other factors such as website content and design, especially in online food shopping. This is [...]![]()
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Salizzoni, Emma ; Pérez Campaña, Rocío ; Alcalde-Rodríguez, Fernando ; Talavera García, Rubén | MDPI | 2020-04-05Although widely, as well as recently explored, the concept of urban resilience still poses important issues in terms of its operationalization. For this reason, best practices that show how the resilience concept has been turned into planning pr[...]![]()
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Agúndez, Dolores ; Nouhoheflin, Théodore ; Coulibaly, Ousmane ; Soliño Millán, Mario ; Alía, Ricardo | MDPI | 2019Shea products in Benin (West Africa) are produced in a low-developed agroindustry, but they are estimated to be the country’s third largest export. The nut harvesting and quality guaranteeing in the butter process can only be achieved through im[...]![]()
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For a locally quasi-convex topological abelian group (G, ?), we study the poset C (G, ?) of all locally quasi-convex topologies on G that are compatible with ? (i.e., have the same dual as (G, ?)) ordered by inclusion. Obviously, this poset has [...]![]()
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We study here several simple models of the electron transfer (ET) in a one-dimensional nonlinear lattice between a donor and an acceptor and propose a new fast mechanism of electron surfing on soliton-like excitations along the lattice. The nonl[...]![]()
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Alonso Conde, Rafael Alejandro ; Celis Rodríguez, Miguel de ; Ruiz Ruiz, Javier ; Vicente Sánchez, Javier ; Navascués, Eva ; Acedo, Alberto ; Ortiz-Álvarez, Rüdiger ; Belda, Ignacio ; Santos de la Sen, Antonio ; Gómez Flechoso, María Angeles ; Marquina Díaz, Domingo | MDPI | 2019-08-29In winemaking processes, there is a current tendency to develop spontaneous fermentations taking advantage of the metabolic diversity of derived from the great microbial diversity present in grape musts. This enological practice enhances wine co[...]![]()
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A direct approach to non-linear second-order ordinary differential equations admitting a superposition principle is developed by means of Vessiot-Guldberg-Lie algebras of a dimension not exceeding three. This procedure allows us to describe gene[...]![]()
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Ruiz-Roso Guerra, María Belén ; Echeverry Alzate, Víctor ; Ruiz-Roso Calvo de la Mora, Baltasar ; Quintela, José ; Ballesteros Rodrigálvarez, Sandra ; Lahera Julia, Vicente ; Heras Jiménez, Natalia de las ; López Moreno, José Antonio ; Martín Fernández, Beatriz | MDPI | 2018Alzheimer’s disease (AD) is the main cause of dementia and cognitive impairment. It has been associated with a significant diminution of omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) levels in the brain. Clinical trials with DHA [...]![]()
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Vida, Carmen ; Kobayashi, Hikaru ; Garrido, Antonio ; Martínez de Toda, Irene ; Carro, Eva ; Molina, José ; Fuente del Rey, Mónica de la | MDPI | 2019-02-12In Parkinson’s Disease (PD), the peripheral changes in the functional capacity and redox state of immune cells has been scarcely investigated, especially in the early PD stages. Aging is a risk factor for PD, and the age-related impairment of th[...]![]()
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Villegas, Fernanda ; Garcia-Uriostegui, Lorena ; Rodríguez, Ofelia ; Izquierdo-Barba, Isabel ; Salinas Sánchez, Antonio J. ; Toriz, Guillermo ; Vallet Regí, María ; Delgado, Ezequiel | MDPI | 2017Abstract: A facile strategy for zwitterionization of bioceramics based on direct incorporation of L-lysine amino acid via the ?-amino group onto mesoporous MCM-41 materials is proposed. FTIR studies of lysine-grafted MCM-41 (MCM-LYS) showed simu[...]![]()
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The study of diagnostic associations entails a large number of methodological problems regarding the application of machine learning algorithms, collinearity and wide variability being some of the most prominent ones. To overcome these, we propo[...]![]()
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López Cuenca, Inés ; Hoz Montañana, Rosa de ; García Martín, Elena Salobrar ; Elvira Hurtado, Lorena ; Rojas Lozano, Pilar ; Fernández Albarral, José Antonio ; Barabash, Ana ; Salazar Corral, Juan José ; Ramírez Sebastián, Ana Isabel ; Ramirez Sebastian, Jose Manuel | MDPI | 2020-06-03In this case control study, we examined the retinal thickness of the different layers in the macular region and peripapillary retinal nerve fiber layer (RNFL) with optical coherence tomography (OCT) in healthy cognitive subjects (from 51 to 74 y[...]![]()
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Lopez, Belen ; Torres Marín, Alfonso Jesús ; Ruozzi López, Alberto ; Vicente, Jose Antonio | MDPI | 2020The objective of this study is to explore empirically the dimensions that generate high impact in the finance industry to better understand its contribution from a Corporate Social Responsibility (CSR) perspective. We analyze data concerning imp[...]![]()
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Cadenas de Llano-Pérula, Maria ; Ricse, Estela ; Fieuws, Steffen ; Willems, Guy ; Orellana-Valvekens, Maria Fernanda | MDPI | 2020-07-14T00:01:00ZRural, isolated areas benefit less from caries prevention programs and access to treatment than urban areas, and, hence, differences in oral health can be expected. This study aims to assess the prevalence of caries and malocclusion in urban and[...]![]()
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Martínez Santos, Pedro ; Martín Loeches, Miguel Martín ; Díaz Alcaide, Silvia ; Danert, Kerstin | MDPI | 2020Water access remains a challenge in rural areas of low-income countries. Manual drilling technologies have the potential to enhance water access by providing a low cost drinking water alternative for communities in low and middle income countrie[...]![]()
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Aubé, Martin ; Marseille, Charles ; Farkouh, Amar ; Dufour, Adam ; Simoneau, Alexandre ; Zamorano Calvo, Jaime ; Roby, Johanne ; Tapia Ayuga, Carlos | MDPI | 2020-12Increased exposure to artificial light at night can affect human health including disruption of melatonin production and circadian rhythms which can extend to increased risks of hormonal cancers and other serious diseases. In addition, multiple [...]![]()
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Martínez Santos, Pedro ; Martín-Loeches, Miguel ; Solera, Daniel ; Cano, Beatriz ; Díaz Alcaide, Silvia | MDPI | 2017While access to water remains an issue in arid and semiarid regions across the world, aquifers have the potential to help millions of people out of poverty by providing a reliable source of drinking and irrigation water. Manual boreholes are inc[...]![]()
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Pesántez-Pacheco, José Luis ; Heras-Molina, Ana ; Torres-Rovira, Laura ; Sanz-Fernández, María Victoria ; García-Contreras, Consolación ; Vázquez Gómez, Marta ; Feyjoo Vico, Pablo ; Cáceres Martín, Elisa ; Frías Mateo, Millán ; Hernández, Fernando ; Martínez-Ros, Paula ; González Martín, Juan Vicente ; González Bulnes, Antonio ; Astiz, Susana | MDPI | 2019-05-30Pregnancy and lactation, especially when concurrent, create a rather metabolically demanding situation in dairy ruminants, but little is known about their effects on offspring phenotype and milk yield. Here, we evaluated the impact of pregnancy [...]![]()
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García-Contreras, Consolación ; Vázquez Gómez, Marta ; Pesántez-Pacheco, José Luis ; Torres-Rovira, Laura ; Heras-Molina, Ana ; Encinas Cerezo, Teresa ; Astiz, Susana ; González Bulnes, Antonio | MDPI | 2019-04-29Metformin is an anti-hyperglycemic drug widely used for the treatment of insulin resistance and glucose intolerance and is currently considered for preventing large-for-gestational-age (LGA) offspring in pregnant women affected by obesity or dia[...]![]()
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Disasters have catastrophic effects on the affected population, especially in developing and underdeveloped countries. Humanitarian Logistics models can help decision-makers to efficiently and effectively warehouse and distribute emergency goods[...]