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González Rubio, Sergio ; Montero Pastor, Nuria ; García, Carolina ; Almendro Vedia, Víctor G. ; Ferrer, Irene ; Natale, Paolo ; Paz-Ares, Luis ; Lillo, M. Pilar ; López-Montero, Iván | Frontiers Media | 2018-11Cancer cell mitochondria represent an attractive target for oncological treatment as they have unique hallmarks that differ from their healthy counterparts, as the presence of a stronger membrane potential that can be exploited to specifically a[...]texto impreso
de la Fuente Herreruela, Diego ; Gónzalez Charro, Vicente ; Almendro Vedia, Víctor G. ; Morán, María ; Martín, Miguel Ángel ; Lillo, M. Pilar ; Natale, Paolo ; López-Montero, Iván | Elsevier | 2017Mitochondria are essential for the production and maintenance of ATP in the eukaryotic cell. To image and monitor intracellular ATP level without cell breakage, biological and chemical sensors were developed in the last years. Here, we have inte[...]texto impreso
Almendro Vedia, Víctor G. ; García, Carolina ; Ahijado Guzmán, Rubén ; de la Fuente Herreruela, Diego ; Muñoz Úbeda, Mónica ; Natale, Paolo ; Viñas, Montserrat H. ; Albuquerque, Rodrigo Queiroz ; Guerrero Martínez, Andrés ; Monroy, Francisco ; Lillo, M. Pilar ; López-Montero, Iván | Elsevier | 2018Background: The fluorescent dye 10-N-nonyl acridine orange (NAO) is widely used as a mitochondrial marker. NAO was reported to have cytotoxic effects in cultured eukaryotic cells when incubated at high concentrations. Although the biochemical re[...]
