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Feito Castellano, María José ; Díez-Orejas, Rosalia ; Cicuendez, Monica ; Casarrubios, Laura ; Rojo, José María ; Portolés Pérez, María Teresa | Elsevier | 2019-04-01Macrophages play a key role in nanoparticle removal and are primarily responsible for their uptake and trafficking in vivo. Due to their functional plasticity, macrophages display a spectrum of phenotypes between two extremes indentified as pro-[...]texto impreso
Díez Orejas, Rosalía ; Casarrubios, Laura ; Feito Castellano, María José ; Rojo, J.M. ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | Elsevier | 2021-02-15The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a[...]texto impreso
Casarrubios, Laura ; Gómez-Cerezo, Natividad ; Feito Castellano, María José ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | Elsevier | 2018-12-01Mesoporous nanospheres in the system SiO2-CaO (NanoMBGs) with a hollow core surrounded by a radial arrangement of mesopores were characterized, labeled with FITC (FITC-NanoMBGs) and loaded with ipriflavone (NanoMBG-IPs) in order to evaluate thei[...]texto impreso
Casarrubios, Laura ; Gomez Cerezo, Natividad ; Feito Castellano, María José ; Vallet Regí, María ; Arcos Navarrete, Daniel ; Portolés Pérez, María Teresa | MDPI | 2020-12-21The incorporation and effects of hollow mesoporous nanospheres in the systemSiO2–CaO (nanoMBGs) containing ipriflavone (IP), a synthetic isoflavone that prevents osteoporosis, were evaluated. Due to their superior porosity and capability to host[...]texto impreso
Gomez Cerezo, Natividad ; Casarrubios, Laura ; Saiz-Pardo, M. ; Ortega, L. ; De Pablo, D. ; Díaz-Güemes, I. ; Fernández-Tomé, E. ; Enciso, S ; Sanchez-Margallo, F. M. ; Portolés Pérez, María Teresa ; Arcos Navarrete, Daniel ; Vallet Regí, María | Elsevier | 2019-04-05Macroporous scaffolds made of a SiO2-CaO-P2O5 mesoporous bioactive glass (MBG) and ?polycaprolactone (PCL) have been prepared by robocasting. These scaffolds showed an excellent in vitro biocompatibility in contact with osteoblast like cells (Sa[...]texto impreso
Casarrubios, Laura ; Matesanz Sancho, María Concepción ; Sánchez Salcedo, Sandra ; Arcos Navarrete, Daniel ; Vallet Regí, María ; Portoles, María Teresa | Elsevier | 2016-11-15Hypothesis: Silicon substituted hydroxyapatites (SiHA) are highly crystalline bioceramics treated at high temperatures (about 1200ºC) which have been approved for clinical use with spinal, orthopedic, periodontal, oral and craniomaxillofacial ap[...]texto impreso
Salinas Sánchez, Antonio J. ; Blanco-Bécares, José M. ; Mersinlioglu, Okan ; Casarrubios, Laura ; Fernández-Villa, Daniel ; Feito Castellano, María José ; Portolés Pérez, María Teresa ; González Ortiz, Blanca ; Vallet Regí, María | Wiley Online Library | 2018-05-25Calcium phosphate (CaP) based hybrid materials have been synthesized through a precipitation method in aqueous medium in the presence of the anionic surfactant sodium dodecylbenzene sulfonate (SDBS) as structure directing agent. Parameters of sy[...]
