texto impreso

Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation

Amrán, Donna ; Sancho, Patricia ; Fernández, Carlos ; Esteban Fernández, Diego ; Ramos, Adrian M. ; Blas, Elena de ; Gómez Gómez, M.Milagros ; Palacios Corvillo, María A. ; Aller, Patricio | Elsevier | 2005

It has been reported that inhibition of extracellular signal-regulated protein kinases (ERKs) attenuates the toxicity cisplatin (cisplatinum (II)-diammine dichloride) in some cell types. This response was here investigated using human myeloid le[...]

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