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Brutsaert, Tom D. ; Kiyamu, Melisa ; Elias Revollendo, Gianpietro ; Isherwood, Jenna L. ; Lee, Frank S. ; Rivera-Ch, Maria ; Leon-Velarde, Fabiola ; Ghosh, Sudipta ; Bigham, Abigail W. | National Academy of Sciences | 2019-12-06T21:02:54ZHighland native Andeans have resided at altitude for millennia. They display high aerobic capacity (VO2max) at altitude, which may be a reflection of genetic adaptation to hypoxia. Previous genomewide (GW) scans for natural selection have nomin[...]texto impreso
Tejada, J.V. ; Flynn, J.J. ; Antoine, P.-O. ; Pacheco, V. ; Salas-Gismondi, R. ; Cerling, T.E. | National Academy of Sciences | 2020-12-14T16:10:17ZClosed-canopy rainforests are important for climate (influencing atmospheric circulation, albedo, carbon storage, etc.) and ecology (harboring the highest biodiversity of continental regions). Of all rainforests, Amazonia is the world's most div[...]texto impreso
Defrance, Dimitri ; Ramstein, Gilles ; Charbit, Sylvie ; Vrac, Mathieu ; Moise Famien, Adjoua ; Sultan, Benjamin ; Swingedouw, Didier ; Dumas, Christophe ; Gemenne, François ; Álvarez Solas, Jorge ; Vanderlinden, Jean-Paul | National Academy of Sciences | 2017-06-20The acceleration of ice sheet melting has been observed over the last few decades. Recent observations and modeling studies have suggested that the ice sheet contribution to future sea level rise could have been underestimated in the latest Inte[...]texto impreso
Gracia Téllez, Ana ; Arsuaga, Juan Luis ; Martínez Mendizábal, Ignacio ; Lorenzo Merino, Carlos ; Carretero, José Miguel ; Bermúdez de Castro, José María ; Carbonell i Roura, Eudald | National Academy of Sciences | 2009-04-21We report here a previously undescribed human Middle Pleistocene immature specimen, Cranium 14, recovered at the Sima de los Huesos (SH) site (Atapuerca, Spain), that constitutes the oldest evidence in human evolution of a very rare pathology in[...]texto impreso
Van den Broeck, F. ; Savill, N.J. ; Imamura, H. ; Sanders, M. ; Maes, I. ; Cooper, S. ; Mateus, D. ; Jara, M. ; Adaui, V. ; Arevalo, J. ; Llanos-Cuentas, A. ; Garcia, L. ; Cupolillo, E. ; Miles, M. ; Berriman, M. ; Schnaufer, A. ; Cotton, J.A. ; Dujardin, J.-C. | National Academy of Sciences | 2020-12-14T16:10:23ZThe tropical Andes are an important natural laboratory to understand speciation in many taxa. Here we examined the evolutionary history of parasites of the Leishmania braziliensis species complex based on whole-genome sequencing of 67 isolates f[...]texto impreso
Caramanica, A. ; Mesia, L.H. ; Morales, C.R. ; Huckleberry, G. ; Luis Jaime Castillo, B. ; Quilter, J. | National Academy of Sciences | 2020-12-14T16:06:12ZEl Niño-Southern Oscillation has been treated as a disruptor of environmental and socioeconomic equilibrium both in ancient times and in modern-day Peru. Recent work in the coastal desert plain, known as the Pampa de Mocan, challenges this view [...]texto impreso
Griffiths, Scott ; Mesarich, Carl-H. ; Saccomanno, Benedetta ; Vaisberg, Abraham ; De-Wit, Pierre-J. G. M. ; Cox, Russell ; Collemare, Jerome | National Academy of Sciences | 2019-02-06T14:45:34ZAnthraquinones are a large family of secondary metabolites (SMs) that are extensively studied for their diverse biological activities. These activities are determined by functional group decorations and the formation of dimers from anthraquinone[...]texto impreso
Masanes, Lluís ; Muller, Markus P. ; Augusiak, Remigiusz ; Pérez García, David | National Academy of Sciences | 2013-10Does information play a significant role in the foundations of physics? Information is the abstraction that allows us to refer to the states of systems when we choose to ignore the systems themselves. This is only possible in very particular fra[...]texto impreso
Valdiosera Morales, Cristina ; Günther, Torsten ; Vera-Rodríguez, Juan Carlos ; Ureña, Irene ; Iriarte, Eneko ; Rodríguez Varela, Ricardo ; Simões, Luciana G. ; Martínez-Sánchez, Rafael María ; Svensson, Emma ; Malmström, Helena ; Rodríguez, Laura ; Bermúdez de Castro, José María ; Carbonell i Roura, Eudald ; Alday Ruiz, Alfonso ; Hernández Vera, José Antonio ; Götherström, Anders ; Carretero, José Miguel ; Arsuaga, Juan Luis ; Smith, Colin I. ; Jakobsson, Mattias | National Academy of Sciences | 2018-03-12Population genomic studies of ancient human remains have shown how modern-day European population structure has been shaped by a number of prehistoric migrations. The Neolithization of Europe has been associated with large-scale migrations from [...]texto impreso
van Dorp, Lucy ; Lowes, Sara ; Weigel, Jonathan L. ; Ansari-Pour, Naser ; López, Saioa ; Mendoza-Revilla, Javier ; Robinson, James A. ; Henrich, Joseph ; Thomas, Mark G. ; Nunn, Nathan ; Hellenthal, Garrett | National Academy of Sciences | 2019-07-04T16:59:36ZFew phenomena have had as profound or long-lasting consequences in human history as the emergence of large-scale centralized states in the place of smaller scale and more local societies. This study examines a fundamental, and yet unexplored, co[...]texto impreso
Álvarez Solas, Jorge ; Robinson, Alexander James ; Montoya Redondo, María Luisa ; Ritz, Catherine | National Academy of Sciences | 2013-10-08Proxy data reveal the existence of episodes of increased deposition of ice-rafted detritus in the North Atlantic Ocean during the last glacial period interpreted as massive iceberg discharges from the Laurentide Ice Sheet. Although these have lo[...]texto impreso
San Martín, Álvaro ; Rodriguez-Aliaga, Piere ; Molina, José Alejandro ; Martin, Andreas ; Bustamante, Carlos ; Báez, Mauricio | National Academy of Sciences | 2019-01-25T15:28:04ZATP-dependent proteases translocate proteins through a narrow pore for their controlled destruction. However, how a protein substrate containing a knotted topology affects this process remains unknown. Here, we characterized the effects of the t[...]texto impreso
Sistiaga, Ainara ; Husain, Fatima ; Uribelarrea del Val, David ; Martín Perea, David ; Ferland, Troy ; Freeman, Katherine H. ; Diez-Martín, Fernando ; Baquedano, Enrique ; Mabulla, Audax ; Domínguez-Rodrigo, Manuel ; Summons, Roger E. | National Academy of Sciences | 2020-10-06Landscape-scale reconstructions of ancient environments within the cradle of humanity may reveal insights into the relationship between early hominins and the changing resources around them. Many studies of Olduvai Gorge during Pliocene–Pleistoc[...]texto impreso
Gonzalez-Guarda, Erwin ; Petermann-Pichincura, Alia ; Tornero, Carlos ; Domingo Martínez, Laura ; Agustí, Jordi ; Pino, Mario ; Abarzúa, Ana M. ; Capriles, José M. ; Villavicencio, Natalia A. ; Labarca, Rafael ; Tolorza, Violeta ; Sevilla, Paloma ; Rivals, Florent | National Academy of Sciences | 2018-09-11Proboscideans are so-called ecosystem engineers and are considered key players in hypotheses about Late Pleistocene megafaunal extinctions. However, knowledge about the autoecology and chronology of the proboscideans in South America is still op[...]texto impreso
Almendro-Vedia, Víctor G. ; Natale, Paolo ; Mell, Michael ; Bonneau, Stephanie ; Monroy Muñoz, Francisco ; Joubert, Frederic ; López-Montero, Iván | National Academy of Sciences | 2017ATP synthase is a rotating membrane protein that synthesizes ATP through proton-pumping activity across the membrane. To unveil the mechanical impact of this molecular active pump on the bending properties of its lipid environment, we have funct[...]
