| Título: | The influence of meibomian gland loss on ocular surface clinical parameters |
| Autores: | Rico del Viejo, Laura ; Benítez del Castillo, José Manuel ; Gómez Sanz, Fernando Javier ; García Montero, María ; Llorens Quintana, Clara ; Madrid Costa, David |
| Tipo de documento: | texto impreso |
| Editorial: | Elsevier, 2019-04-10 |
| Dimensiones: | application/pdf |
| Nota general: |
info:eu-repo/semantics/openAccess cc_by_nc_nd info:eu-repo/semantics/openAccess |
| Idiomas: | |
| Palabras clave: | Estado = Publicado , Materia = Ciencias Biomédicas: Óptica y optometría: Anatomía ocular , Materia = Ciencias Biomédicas: Óptica y optometría: Óptica fisiológica , Materia = Ciencias Biomédicas: Óptica y optometría: Técnicas de la imagen , Tipo = Artículo |
| Resumen: |
Purpose: To assess the relationship between the meibomian gland loss (MGL) and relevant ocular surface clinical parameters as well as the influence of age in this relationship. Methods: A total of 161 participants (mean age; 42±17 years) were enrolled in this study. Infrared meibography was performed using Keratograph 5M (K5M; Oculus GmbH, Wetzlar). Participants were divided into five groups according to total meiboscore and the ocular surface parameters of each MGL group were studied. In addition, the relationship between MGL and the ocular surface parameters was established including age as covariant. Results: Both eyelids were taken into account since no association between the MGL from upper and lower eyelid was found (k value=0.2; p=0.3) despite they were significantly correlated (r= 0.3; p Conclusions: MGL higher than 50% seems to be accompanied by signs on the ocular surface. Furthermore, age demonstrated to be a relevant factor when assessing MGL. For this reason, future studies should compare age-matched groups in order to know the contribution of the MGL on the ocular surface and establish valid cut-off values for dry eye diagnosis. |
| En línea: | https://eprints.ucm.es/id/eprint/55124/1/Laura%20Rico_Preprint_CLAE_2018_356_Original_V0.pdf |
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