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Título:
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Self-Immolative Polymers as novel pH-responsive gate keepers for drug delivery
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Autores:
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Gisbert Garzarán, Miguel ;
Lozano Borregón, Daniel ;
Vallet Regí, María ;
Manzano García, Miguel
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Tipo de documento:
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texto impreso
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Editorial:
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Royal Society of Chemistry, 2016-12-07
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Dimensiones:
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application/pdf
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Nota general:
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cc_by
info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = En prensa
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Materia = Ciencias: Química: Materiales
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Materia = Ciencias: Química: Química inorgánica
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Tipo = Artículo
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Resumen:
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A novel pH-sensitive nanocarrier based on mesoporous silica nanoparticles with self-immolative polymers blocking the pore openings is presented. Triggered release by acid pH is demonstrated, together with their in vitro biocompatibility and effective cell internalisation, which makes this new material a promising candidate for future applications in cancer treatment.
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En línea:
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https://eprints.ucm.es/id/eprint/40875/1/05_201701_MG_RSCAD_Self-Immolative%20Polymers%20as%20novel%20pH-responsive%20gate%20keepers%20for%20drug%20delivery.pdf
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