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Autor Slotte, J. Peter |
Documentos disponibles escritos por este autor (13)
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Alm, Ida ; García Linares, Sara ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | Elsevier | 2015-04The pore forming capacity of Sticholysin II (StnII; isolated from Stichodactyla helianthus) in bilayer membranes containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), palmitoylsphingomyelin (PSM) and either cholesterol or palmitoyl[...]texto impreso
Palacios Ortega, Juan ; García Linares, Sara ; Rivera de la Torre, Esperanza ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | ACS | 2017In this study, we examined the influence of bilayer thickness on the activity of the actinoporin toxins sticholysin I and II (StnI and StnII) at 25 °C. Bilayer thickness was varied using dimonounsaturated phosphatidylcholine (PC) analogues (with[...]texto impreso
García-Linares, Sara ; Rivera de la Torre, Esperanza ; Morante, Koldo ; Tsumoto, Kouhei ; Caaveiro, José M. M. ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | American Chemical Society | 2016-11Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins (PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII, respectively), produced by three different sea anemone specie[...]texto impreso
Roldán López, Nuria ; Nyholm, Thomas K. M. ; Slotte, J. Peter ; Pérez Gil, Jesús ; García Álvarez, Begoña | BIOPHYSICAL SOCIETY | 2016-10-18To allow breathing and prevent alveolar collapse, lung surfactant (LS) develops a complex membranous system at the respiratory surface. LS is defined by a specific protein and lipid composition, including saturated and unsaturated phospholipid s[...]texto impreso
Palacios Ortega, Juan ; Rivera-de-Torre, Esperanza ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | Elsevier | 2020-04-21Release of aqueous contents from model lipid vesicles has been a standard procedure to evaluate pore formation efficiency by actinoporins, such as sticholysin II (StnII), for the last few decades. However, regardless of the probe of choice, the [...]texto impreso
Palacios Ortega, Juan ; Rivera de la Torre, Esperanza ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | Elsevier | 2020-09-01Release of aqueous contents from model lipid vesicles has been a standard procedure to evaluate pore formation efficiency by actinoporins, such as sticholysin II (StnII), for the last few decades. However, regardless of the probe of choice, the [...]texto impreso
Rivera de la Torre, Esperanza ; Palacios Ortega, Juan ; Slotte, J. Peter ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; García Linares, Sara | MDPI | 2020-11Venoms constitute complex mixtures of many different molecules arising from evolution in processes driven by continuous prey–predator interactions. One of the most common compounds in these venomous cocktails are pore-forming proteins, a family [...]texto impreso
Al Sazzad, Md. Abdullah ; Möuts, Anna ; Palacios Ortega, Juan ; Lin, Kai-Lan ; Nyholm, Thomas K. M. ; Slotte, J. Peter | Elsevier | 2019-03-19The mode of interactions between palmitoyl lysophosphatidylcholine (palmitoyl lyso-PC) or other lysophospholipids (lyso-PLs) and palmitoyl ceramide (PCer) or other ceramide analogs in dioleoylphosphatidylcholine (DOPC) bilayers has been examined[...]texto impreso
Palacios Ortega, Juan ; García Linares, Sara ; Astrand, Mia ; Abdullah Al Sazzad, Md. ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | ACS | 2016Sticholysin II (StnII) is a pore-forming toxin that uses sphingomyelin (SM) as the recognition molecule in targeting membranes.After StnII monomers bind to SM, several toxin monomers act in concert to oligomerize into a functional pore. The regu[...]texto impreso
Palacios Ortega, Juan ; García Linares, Sara ; Rivera de la Torre, Esperanza ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | Elsevier | 2019-06-18Actinoporins are a group of soluble toxic proteins that bind to membranes containing sphingomyelin (SM) and oligomerize to form pores. Sticholysin II (StnII) is a member of the actinoporin family, produced by Stichodactyla helianthus. Cholestero[...]texto impreso
Rivera de Torre, Esperanza ; Palacios Ortega, Juan ; Garb, Jessica E. ; Slotte, J. Peter ; Gavilanes, José G. ; Martínez del Pozo, Álvaro | Elsevier | 2020Actinoporins are a family of pore-forming toxins produced by sea anemones as part of their venomous cocktail. These proteins remain soluble and stably folded in aqueous solution, but when interacting with sphingomyelin-containing lipid membranes[...]texto impreso
García-Linares, Sara ; Alm, Ida ; Maula, Terhi ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | MDPI | 2015Actinoporins are ?-pore forming proteins with therapeutic potential, produced by sea anemones. Sticholysin II (StnII) from Stichodactyla helianthus is one of its most extensively characterized members. These proteins remain stably folded in wate[...]texto impreso
García Linares, Sara ; Palacios Ortega, Juan ; Yasuda, Tomokazu ; Astrand, Mia ; Gavilanes, José G. ; Martínez del Pozo, Álvaro ; Slotte, J. Peter | Elsevier | 2016-03-11Sticholysin I and II (StnI and StnII) are pore-forming toxins that use sphingomyelin (SM) for membrane binding. We examined how hydrogen bonding among membrane SMs affected the StnI- and StnII-induced pore formation process, resulting in bilayer[...]