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Alique, Matilde ; Sánchez-López, E. ; Bodega, Guillermo ; Giannarelli, Chiara ; Carracedo, Julia ; Ramírez, Rafael | MDPI | 2020-01-13Aging is one of the hottest topics in biomedical research. Advances in research and medicine have helped to preserve human health, leading to an extension of life expectancy. However, the extension of life is an irreversible process that is acco[...]texto impreso
Vida, Carmen ; Carracedo Añón, Julia ; Sequera, Patricia de ; Bodega, Guillermo ; Pérez, Rafael ; Alique, Matilde ; Ramírez, Rafael | MDPI | 2020-04-15Oxidative stress is exacerbated in hemodialysis patients by several factors, including the uremic environment and the use of dialysis fluids (DFs). Since magnesium (Mg) plays a key role in modulating immune function and in reducing oxidative str[...]texto impreso
Carracedo, Julia ; Alique, Matilde ; Vida, Carmen ; Bodega, Guillermo ; Ceprián, Noemí ; Morales, Enrique ; Praga, Manuel ; Sequera, Patricia de ; Ramírez, Rafael | Frontiers Media | 2020-03-20Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory process such as atherosclerosis, remain the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). CKD is a systemic condition af[...]texto impreso
Alique, Matilde ; Bodega, Guillermo ; Giannarelli, Chiara ; Carracedo, Julia ; Ramírez, Rafael | Nature Research | 2019-05-14Whereas a healthy endothelium maintains physiological vascular functions, endothelial damage contributes to the development of cardiovascular diseases. Endothelial senescence is the main determinant of endothelial dysfunction and thus of age-rel[...]texto impreso
Alique, Matilde ; Bodega, Guillermo ; Corchete, Elena ; García-Menéndez, Estefanya ; Sequera, Patricia de ; Luque, Rafael ; Rodríguez-Padrón, Daily ; Marqués, María ; Portolés, José ; Carracedo Añón, Julia María ; Ramírez, Rafael | Computational and Structural Biotechnology Journal | 2020-04-09Vascular calcification (VC), an unpredictable pathophysiological process and critical event in patients with cardiovascular diseases (CVDs), is the leading cause of morbi-mortality and disability in chronic kidney disease (CKD) patients worldwid[...]texto impreso
Bodega, G. ; Alique, Matilde ; Puebla, L. ; Carracedo Añón, Julia María ; Ramírez, R. M. | Taylor & Francis | 2019-06-17This review analyzes the relationship between microvesicles and reactive oxygen species (ROS). This relationship is bidirectional; on the one hand, the number and content of microvesicles produced by the cells are affected by oxidative stress co[...]texto impreso
Carracedo Añón, Julia María ; Ramírez-Carracedo, Rafael ; Martínez de Toda, Irene ; Vida Rueda, Carmen ; Alique, Matilde ; Fuente del Rey, Mónica de la ; Ramírez-Chamond, Rafael | MDPI | 2018-05-17Carbamylation is a post-translational modification of proteins that may partake in the oxidative stress-associated cell damage, and its increment has been recently proposed as a “hallmark of aging”. The molecular mechanisms associated with aging[...]texto impreso
Alique, Matilde ; Ramírez-Carracedo, Rafael ; Bodega, Guillermo ; Carracedo Añón, Julia María ; Ramírez, Rafael | MDPI | 2018-07-09Atherosclerosis, a chronic inflammatory disease that causes the most heart attacks and strokes in humans, is the leading cause of death in the developing world; its principal clinical manifestation is coronary artery disease. The development of [...]
