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The decrease in the proliferative response of lymphocytes is one of the most evident among the age-related changes of the immune system. This has been linked to a higher risk of mortality in both humans and experimental animals. However, long-li[...]texto impreso
Vida, Carmen ; Kobayashi, Hikaru ; Garrido, Antonio ; Martínez de Toda, Irene ; Carro, Eva ; Molina, José ; Fuente del Rey, Mónica de la | MDPI | 2019-02-12In Parkinson’s Disease (PD), the peripheral changes in the functional capacity and redox state of immune cells has been scarcely investigated, especially in the early PD stages. Aging is a risk factor for PD, and the age-related impairment of th[...]texto impreso
Carracedo Añón, Julia María ; Ramírez-Carracedo, Rafael ; Martínez de Toda, Irene ; Vida Rueda, Carmen ; Alique, Matilde ; Fuente del Rey, Mónica de la ; Ramírez-Chamond, Rafael | MDPI | 2018-05-17Carbamylation is a post-translational modification of proteins that may partake in the oxidative stress-associated cell damage, and its increment has been recently proposed as a “hallmark of aging”. The molecular mechanisms associated with aging[...]
