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Feito Castellano, María José ; Díez-Orejas, Rosalia ; Cicuendez, Monica ; Casarrubios, Laura ; Rojo, José María ; Portolés Pérez, María Teresa | Elsevier | 2019-04-01Macrophages play a key role in nanoparticle removal and are primarily responsible for their uptake and trafficking in vivo. Due to their functional plasticity, macrophages display a spectrum of phenotypes between two extremes indentified as pro-[...]texto impreso
Cicuendez, Monica ; Portoles, Pilar ; Montes Casado, María ; Izquierdo-Barba, Isabel ; Vallet Regí, María ; Portolés Pérez, María Teresa | Royal Society of Chemistry | 2014-06-14The interaction of new nanocomposite mesoporous glass/hydroxyapatite (MGHA) scaffolds with immune cells involved in both innate and acquired immunity has been studied in vitro as an essential aspect of their biocompatibility assessment. Since th[...]texto impreso
Cicuendez, Monica ; Fernándes, Márcia ; Ayán-Varela, Miguel ; Oliveira, Helena ; Feito Castellano, María José ; Díez Orejas, Rosalía ; Paredes, Juan I. ; Villar-Rodil, Silvia ; Vila, Mercedes ; Portolés Pérez, María Teresa ; Duarte, Iola F. | Elsevier | 2020-02The preparation of graphene-based nanomaterials (GBNs) with appropriate stability and biocompatibility is crucial for their use in biomedical applications. In this work, three GBNs differing in size and/or functionalization have been synthetized[...]texto impreso
Martínez, Angel ; Fuentes Paniagua, Elena ; Baeza, Alejandro ; Sánchez Nieves, Javier ; Cicuendez, Monica ; Gómez, Rafael ; Mata, F. Javier de la ; González, Blanca ; Vallet Regí, María | Wiley | 2015-09-15A novel nanosystem based on mesoporous silica nanoparticles covered with carbosilane dendrons grafted on the external surface of the nanoparticles is reported. This system is able to transport single-stranded oligonucleotide into cells, avoiding[...]texto impreso
Cicuendez, Monica ; Flores, Joana ; Oliveira, Helena ; Portolés Pérez, María Teresa ; Vallet Regí, María ; Vila, Mercedes ; Duarte, Lola F | Elsevier | 2018-05-18Nanographene oxide (nGO)-mediated hyperthermia has been increasingly investigated as a localized, minimally invasive anticancer therapeutic approach. Near InfraRed (NIR) light irradiation for inducing hyperthermia is particularly attract[...]texto impreso
Cicuendez, Monica ; Doadrio Villarejo, Juan Carlos ; Hernandez, ana ; Portolés Pérez, María Teresa ; Izquierdo-Barba, Isabel ; Vallet Regí, María | Elsevier | 2017-11-09Multifunctional-therapeutic three-dimensional (3D) scaffolds have been prepared. These biomaterials are able to destroy the S. aureus bacterial biofilm and to allow bone regeneration at the same time. The present study is focused on the design o[...]
