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Martínez Carmona, Marina ; Qui P., Ho ; Morand, Jeremy ; García Fontecha, Ana ; Ortega, Enrique ; Luiza C.S., Erthal ; Ruiz-Hernandez, Eduardo ; Santana, Dolores M. ; Ruiz, José ; Vallet Regí, María ; Gun’ko, Yurii | American Chemical Society | 2020-07-06In the process of synthesis of a new drug, as important as the drug itself is the formulation used, because the same compound can present a very different efficacy depending on how it is administered. In this work, we demonstrate how the antitum[...]texto impreso
Delpiano, Giulia ; Casula, Maria ; Piludu, Marco ; Corpino, Riccardo ; Ricci, Pier Carlo ; Vallet Regí, María ; Sanjust, Enrico ; Monduzzi, Maura ; Salis, Andrea | American Chemical Society | 2019-06-25The purpose of this work was the assembly of multicomponent nano-bioconjugates based on mesoporous silica nanoparticles (MSNs), proteins (bovine serum albumin, BSA, or lysozyme, LYZ), and gold nanoparticles (GNPs). These nanobioconjugates may fi[...]texto impreso
Vilhena, J.G. ; Pimentel, Carlos ; Pedraz, Patricia ; Luo, Feng ; Serena, Pedro A. ; Pina Martínez, Carlos Manuel ; Gnecco, Enrico ; Pérez, Rubén | American Chemical Society | 2016The sliding of a sharp nanotip on graphene completely immersed in water is investigated by molecular dynamics (MD) and atomic force microscopy. MD simulations predict that the atomicscale stick?slip is almost identical to that found in ultrahigh[...]texto impreso
Guisasola, Eduardo ; Asin, Laura ; Beola, Lillianne ; De la Fuente, J. M. ; Baeza, Alejandro ; Vallet Regí, María | American Chemical Society | 2018-03-21In this study we present an innovation in the tumor treatment in vivo mediated by magnetic mesoporous silica nanoparticles (MMSNs). This device was built with iron oxide magnetic nanoparticles embedded in a mesoporous silica matrix and coated wi[...]texto impreso
Castillo, Rafael R. ; Lozano Borregón, Daniel ; Vallet Regí, María | American Chemical Society | 2018-10-01ABSTRACT: Despite encapsulation of drugs claim to improve the therapeutic profile of free drugs, there are still important limitations in drug delivery. Focusing on cancer treatment, two promising implementations are combination therapy and targ[...]texto impreso
Valencia Ayala, Edward ; Rodrigues da Cunha, Gisele ; Araujo Azevedo, Maira ; Calderón, Maritza ; Jimenez, Juan ; Venuto, Ana Paula ; Gazzinelli, Ricardo ; Ynocente Lavalle, Raúl Jesus ; Vidal Riva, Angela Giovana ; Hincapie, Robert ; Finn, M. G. ; Marques, Alexandre F. | American Chemical Society | 2020-07-14T00:02:36ZThe leading animal model of experimental Chagas disease, the mouse, plays a significant role in studies for vaccine development, diagnosis, and human therapies. Humans, along with Old World primates, alone among mammals, cannot make the terminal[...]texto impreso
Reales Calderón, José Antonio ; Vaz, Catarina ; Monteoliva Díaz, Lucía ; Molero, Gloria ; Gil, Concha | American Chemical Society | 2016-10-14The effectiveness of macrophages in the response to systemic candidiasis is crucial to an effective clearance of the pathogen. The secretion of proteins, mRNAs, non-coding RNAs and lipids through extracellular vesicles (EVs) is one of the mechan[...]texto impreso
Gartzia-Rivero, Leire ; Ray Leiva, César ; Sánchez Carnerero, Esther M. Márquez ; Bañuelos, Jorge ; Moreno Jiménez, Florencio ; Lora Maroto, Beatriz ; García Moreno, Inmacualada ; Infantes, Lourdes ; Méndez Martín, Bianchi ; López Arbeloa, Íñigo María | American Chemical Society | 2019-04-09Supramolecular self-assembly of a highly flexible and achiral meso bis(boron dipyrromethene) [bis-(BODIPY)] dye straightforwardly yields fluorescent micro-fibers, exhibiting an intriguing anisotropic photonic behavior. This performance includes [...]texto impreso
Fernández García, Jesús M. ; Evans, Paul J. ; Filippone, Salvatore ; Herranz, M.Angeles ; Martín, Nazario | American Chemical Society | 2019-06Chirality is a fascinating property present in naturally occurring and artificial molecules and materials, observable as chiroptical behavior. The emerging area of carbon nanostructures has undergone tremendous development, with a wide variety o[...]texto impreso
Greiner, Martina ; Yin, Xiaofei ; Fernández-Díaz, Lourdes ; Griesshaber, Erika ; Weitze, Florian ; Ziegler, Andreas ; Veintemillas-Verdaguer, Sabino ; Schmahl, Wolfgang W. | American Chemical Society | 2018-01-30We report results of CaCO3 crystallization experiments by counter diffusion in agar gel with two different solid contents (0.5 and 2 wt %) and two solute concentrations (0.1 M CaCl2, 0.1 M Na2CO3; 0.5 M CaCl2, 0.5 M Na2CO3). Solute concentration[...]texto impreso
Moreno, Marta ; Tong-Rios, Carlos ; Orjuela-Sanchez, Pamela ; Carrasco-Escobar, Gabriel ; Campo, Brice ; Gamboa, Dionicia ; Winzeler, Elizabeth A. ; Vinetz, Joseph M. | American Chemical Society | 2018-11-30T02:09:31ZIn vitro culture of Plasmodium vivax liver stages underlies key understandings of the fundamental biology of this parasite, particularly the latent, hyponozoite stage, toward drug and vaccine development. Here, we report systematic production of[...]texto impreso
Birame Gueye, Papa Gorgui ; López Sánchez, Jesús ; Navarro Palma, Elena ; Serrano, Aída ; Marín Palacios, María Pilar | American Chemical Society | 2020-04-01A combination of high-energy ball milling, vacuum filtering, and sedimentation processes has been demonstrated to be a useful approach to reduce, in a controlled way, the length of as-cast Fe_(73.5)Si_(13.5)Nb_3Cu_1B_9 amorphous magnetic microwi[...]texto impreso
Sanz, L. ; Quesada-Bernat, S. ; Pérez, A. ; De Morais-Zani, K. ; SantEänna, S.S. ; Hatakeyama, D.M. ; Tasima, L.J. ; De Souza, M.B. ; Kayano, A.M. ; Zavaleta, A. ; Salas, M. ; Soares, A.M. ; Calderón, L.D.A. ; Tanaka-Azevedo, A.M. ; Lomonte, B. ; Calvete, J.J. ; Caldeira, C.A.S. | American Chemical Society | 2020-12-14T16:10:10ZWe report a structural and functional proteomics characterization of venoms of the two subspecies (Bothrops bilineatus bilineatus and B. b. smaragdinus) of the South American palm pit viper from the Brazilian state of Rondônia and B. b. smaragdi[...]texto impreso
Orjuela-Sanchez, Pamela ; Villa, Zaira Hellen ; Moreno, Marta ; Tong-Rios, Carlos ; Meister, Stephan ; LaMonte, Gregory M. ; Campo, Brice ; Vinetz, Joseph M. ; Winzeler, Elizabeth A. | American Chemical Society | 2018-11-30T03:10:44ZTo develop new drugs and vaccines for malaria elimination, it will be necessary to discover biological interventions, including small molecules that act against Plasmodium vivax exoerythrocytic forms. However, a robust in vitro culture system fo[...]texto impreso
García-Linares, Sara ; Rivera de la Torre, Esperanza ; Morante, Koldo ; Tsumoto, Kouhei ; Caaveiro, José M. M. ; Gavilanes, José G. ; Slotte, J. Peter ; Martínez del Pozo, Álvaro | American Chemical Society | 2016-11Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins (PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII, respectively), produced by three different sea anemone specie[...]
