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Thermodynamic analysis of the binding of 5-fluoro-2'-deoxyuridine 5'-monophosphate to thymidylate synthase over a range of temperatures

García Fuentes, Luis ; Reche, Pedro A ; López Mayorga, O ; Santi, D V ; González-Pacanowska, D. ; Barón, C | Wiley InterScience | 1995

The binding of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP) to Lactobacillus casei recombinant thymidylate synthase has been studied by isothermal titration microcalorimetry at pH 7.1 over the temperature range 16-35 degrees C. Calorimetric[...]

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