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Navarro, Pedro ; Trevisan Herraz, Marco ; Bonzon Kulichenko, Elena ; Núñez, Estefanía ; Martínez Acedo, Pablo ; Pérez Hernández, Daniel ; Jorge, Inmaculada ; Mesa, Raquel ; Calvo, Enrique ; Carrascal, Montserrat ; Hernaez, Maria Luisa ; García, Fernando ; Bárcena, José Antonio ; Ashman, Keith ; Abian, J. ; Gil, Concha ; Redondo, Juan Miguel ; Vázquez, Jesús | American Chemical Society | 2014-01-31The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures. However, interpretation of the large data sets generated by these techniques remains a [...]texto impreso
Martínez Santos, Paula, Paula ; Baldán Martín, Montserrat ; López, Juan A. ; Martín Lorenzo, Marta ; Santiago Hernández, Aránzazu ; Agudieza, Marta ; Cabrera Sierra, Martha ; Calvo, Eva ; Vázquez, Jesús ; Ruiz Hurtado, Gema ; Vivanco, Fernando ; Ruilope, Luis M ; Barderas, María G. ; Alvarez-Llamas, Gloria | Elsevier | 2019-03Background and aims The predictive value of traditional CV risk calculators is limited. Novel indicators of CVD progression are needed particularly in the young population. The main aim of this study was the identification of a molecular profile[...]texto impreso
Tomás-Loba, Antonia ; Manieri, Elisa ; González-Terán, Bárbara ; Mora, Alfonso ; Leiva-Vega, Luis ; Santamans, Ayelén M. ; Romero-Becerra, Rafael ; Rodríguez, Elena ; Pintor-Chocano, Aránzazu ; Feixas, Ferran ; López, Juan Antonio ; Caballero, Beatriz ; Trakala, Marianna ; Blanco, Óscar ; Torres, Jorge L. ; Hernández-Cosido, Lourdes ; Montalvo-Romeral, Valle ; Matesanz, Nuria ; Roche-Molina, Marta ; Bernal, Juan Antonio ; Mischo, Hannah ; León, Marta ; Caballero, Ainoa ; Miranda-Saavedra, Diego ; Ruiz-Cabello, Jesús ; Nevzorova, Yulia A. ; Cubero, Francisco Javier ; Bravo, Jerónima ; Vázquez, Jesús ; Malumbres, Marcos ; Marcos, Miguel ; Osuna, Silvia ; Sabio, Guadalupe | Nature Research | 2019-04-10The cell cycle is a tightly regulated process that is controlled by the conserved cyclin-dependent kinase (CDK)–cyclin protein complex1. However, control of the G0-to-G1 transition is not completely understood. Here we demonstrate that p38 MAPK [...]texto impreso
Martín Lorenzo, Marta ; Martínez, Paula J. ; Baldán Martín, Montserrat ; López, Juan A. ; Mínguez, Pablo ; Santiago Hernández, Aránzazu ; Vázquez, Jesús ; Segura, Julián ; Ruiz Hurtado, Gema ; Vivanco, Fernando ; Barderas, María G. ; Ruilope, Luis M ; Alvarez-Llamas, Gloria | American Heart Association | 2019-02-04Resistant hypertension prevalence is progressively increasing, and prolonged exposure to suboptimal blood pressure control results in higher cardiovascular risk and end-organ damage. Among various antihypertensive agents, spironolactone seems th[...]
