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Muñoz, Juan José ; García Ceca Hernández, Javier ; Montero Herradón, Sara ; Sánchez del Collado, Beatriz ; Alfaro Sánchez, David ; Zapata González, Agustín | Frontiers Media | 2018-04-03For a long time, the effects of distinct Eph tyrosine kinase receptors and their ligands, ephrins on the structure, immunophenotype, and development of thymus and their main cell components, thymocytes (T) and thymic epithelial cells (TECs), hav[...]texto impreso
Cejalvo, Teresa ; Muñoz, Juan J. ; Tobajas, Esther ; Alfaro Sánchez, David ; García Ceca Hernández, Javier ; Zapata González, Agustín | Springer Link | 2015-05Our understanding about medullary compartment, its niches composition and formation is still limited. Previous studies using EphB2 and/or EphB3 knockout mice showed an abnormal thymic development that affects mainly to the epithelial component, [...]texto impreso
Morona Arribas, Ruth ; González Gallegos, Agustín ; Gutiérrez Cañas, Irene ; García-Ceca Hernández, José Javier ; López Redondo, Jesús María ; Alfaro Sánchez, David ; Muñiz Hernando, Enriqueta ; Carrión Caballo, Mar ; Moreno García, Nerea ; Pérez García, Selene ; Pérez Gomáriz, Rosa María | 2018-05-31Histoteca digital para que los alumnos puedan consultar un material gráfico actualizado y concreto, similar a lo que observan en el microscopio cuando realizan sus prácticas de Organografía de la asignatura de “Organografía microscópica” del Gra[...]texto impreso
Alfaro Sánchez, David ; Rodríguez Sosa, Mariano R. ; Zapata González, Agustín Gregorio | MDPI | 2020-01-22Mesenchymal stromal/stem cells (MSCs) have emerged as important therapeutic agents, owing to their easy isolation and culture, and their remarkable immunomodulatory and anti-inflammatory properties. However, MSCs constitute a heterogeneous cell [...]texto impreso
García Ceca Hernández, Javier ; Alfaro Sánchez, David ; Montero Herradón, Sara ; Tobajas, Esther ; Muñoz, Juan José ; Zapata González, Agustín | Frontiers Media | 2015-06-26Numerous studies emphasize the relevance of thymocyte–thymic epithelial cell (TECs) interactions for the functional maturation of intrathymic T lymphocytes. The tyrosine kinase receptors, Ephs (erythropoietin-producing hepatocyte kinases) and th[...]texto impreso
Alfaro Sánchez, David ; Garcia Ceca Hernández, José Javier ; Farias de Oliveira, Desio A. ; Terra Granado, Eugenia ; Montero Herradón, Sara ; Cotta de Almeida, Vinicius ; Savino, Wilson ; Zapata González, Agustín | 2015-02Adult thymuses lacking either ephrin type B receptor 2 (EphB2) or EphB3, or expressing a truncated form of EphB2, the forward signal-deficient EphB2LacZ, have low numbers of early thymic progenitors (ETPs) and are colonized in vivo by reduced nu[...]texto impreso
Garcia-Ceca Hernández, Javier ; Montero Herradón, Sara ; Alfaro Sánchez, David ; Zapata González, Agustín | Springer Link | 2017-05-24Epithelial-free areas, present in both thymic cortex and medulla, have been studied in WT and EphB-deficient mice that have important alterations in the development of thymic epithelium due to the lack of proper thymocyte–thymic epithelial cell [...]texto impreso
Fañanas-Baquero, Sara ; Orman, Israel ; Becerra Aparicio, Federico ; Bermudez de Miguel, Silvia ; Garcia Merino, Jordi ; Yañez, Rosa ; Fernández Sainz, Yolanda ; Sánchez, Rebeca ; Dessy-Rodríguez, Mercedes ; Alberquilla, Omaira ; Alfaro Sánchez, David ; Zapata González, Agustín ; Bueren, Juan A. ; Segovia, Jose Carlos ; Quintana-Bustamante, Oscar | Ferrata Storti Foundation | 2020-04Hematopoietic Stem and Progenitor Cells are crucial in the maintenance of lifelong production of all blood cells. These Stem Cells are highly regulated to maintain homeostasis through a delicate balance between quiescence, self-renewal and diffe[...]texto impreso
Este proyecto pretende facilitar el aprendizaje y mejorar los conocimientos de los alumnos del Grado en Biología sobre los temas tratados en las prácticas de Biología Celular, mediante la elaboración de diverso material docente adicional.
