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In this work we succintly review the main features of bone formation in vertebrates. Out of the many aspects of this exceedingly complex process, some particular stages are selected for which mathematical modelling appears as both feasible and d[...]texto impreso
Herrero, Miguel A. ; Oleaga Apadula, Gerardo Enrique ; Echeverri, L.F. ; López, J. M. | Springer | 2014-12This work is concerned with the sequence of events taking place during the first stages of bone fracture healing, from bone breakup until the formation of early fibrous callus (EFC). The latter provides a scaffold over which subsequent remodelin[...]texto impreso
Fasano, A. ; Herrero, Miguel A. ; López, J. M. ; Medina Reus, Elena | Italian Society for Applied and Industrial Mathematics (SIMAI) | 2010A mathematical model to describe the process of formation of bone tissue by replacement of cartilage tissue is presented and discussed. This model is based on an absorption-diffusion system which describes the interaction of two key signalling m[...]texto impreso
In this work a mathematical model for the interaction of two key signalling molecules in rat tibia ossification is presented and discussed. The molecules under consideration are Indian hedgehog (Ihh) and parathyroid hormone-related peptide (PTHr[...]
