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Bravo Osuna, Irene ; Andrés-Guerrero, Vanessa ; Arranz-Romera, Alicia ; Esteban Pérez, Sergio ; Molina-Martínez, Irene T. ; Herrero-Vanrell, Rocio | Elsevier | 2018-02-15Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These diseases include age-related macular degeneration (AMD), diabetic Retinopathy (DR) and glaucoma, among others. Also, there are genetic disorders[...]texto impreso
Herrero-Vanrell, Rocio ; Vicario de la Torre, Marta ; Andrés-Guerrero, Vanessa ; Barbosa-Alfaro, Deyanira ; Molina-Martínez, Irene Teresa ; Bravo-Osuna, Irene | Elsevier | 2013Ocular drug delivery is one of the most challenging fields of pharmaceutical research. They are generally employed to overcome the static (different layers of cornea, sclera, and retina including blood aqueous and blood-retinal barriers) and dyn[...]texto impreso
Bravo-Osuna, Irene ; Vicario-de-la-Torre, Marta ; Andrés-Guerrero, Vanessa ; Sánchez-Nieves, Javier ; Guzmán-Navarro, Manuel ; de la Matad, F. Javier ; Gómez, Rafael ; de las Heras, Beatriz ; Argüesoh, Pablo ; Poncheli, Gilles ; Herrero-Vanrell, Rocio ; Molina-Martínez, Irene Teresa | American Chemical Society (ACS) | 2016-09-06Purpose: To determine the potential use of water-soluble anionic and cationic carbosilane dendrimers (Generations 1-3) as mucoadhesive polymers in eyedrop formulations. Methods: Cationic carbosilane dendrimers decorated with ammonium –NH3 + gro[...]texto impreso
Bravo-Osuna, Irene ; Andrés-Guerrero, Vanessa ; Pastoriza Abal, Pilar ; Molina-Martínez, I.T. ; Herrero-Vanrell, R. | 2016-12Efficient treatment of ocular diseases can be achieved thanks to the proper use of ophthalmic formulations based on emerging pharmaceutical approaches. Among them, microtechnology and nanotechnology strategies are of great interest in the develo[...]texto impreso
Herrero-Vanrell, Rocio ; Bravo-Osuna, Irene ; Andrés-Guerrero, Vanessa ; Vicario-de-la-Torre, Marta ; Molina-Martínez, Irene Teresa | Elsevier | 2014-09Pathologies affecting the posterior segment are one of the major causes of blindness in developed countries and are becoming more prevalent due to the increase in society longevity. Sucessful therapy of diseases affecting the back of the eye req[...]texto impreso
Esteban Pérez, Sergio ; Bravo Osuna, Irene ; Andrés-Guerrero, Vanessa ; Molina-Martínez, Irene T. ; Herrero-Vanrell, Rocio | Bentham Science | 2019-09-05The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to bi[...]
