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García Martín, Elena Salobrar ; Hoyas, Irene ; Leal, Mercedes ; Hoz Montañana, María Rosa de ; Rojas López, María Blanca ; Ramírez Sebastián, Ana Isabel ; Salazar Corral, Juan José ; Yubero Pancorbo, Raquel ; Gil, Pedro ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Hindawi Publising Corp. | 2015-06-08Decreased thickness of the retinal nerve fiber layer (RNFL) may reflect retinal neuronal-ganglion cell death. A decrease in the RNFL has been demonstrated in Alzheimer’s disease (AD) in addition to aging by optical coherence tomography (OCT). Tw[...]texto impreso
García Martín, Elena Salobrar ; Rojas López, Blanca ; Ramírez Sebastián, Ana Isabel ; Hoz Montañana, Rosa de ; Salazar Corral, Juan José ; Yubero Pancorbo, Raquel ; Gil, Pedro ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Elsevier / American Academy of Ophthalmology | 2014-03-18Although several postmortem findings in the retina of patients with Alzheimer's disease (AD) are available, new biomarkers for early diagnosis and follow-up of AD are still lacking. It has been postulated that the defects in the retinal nerve fi[...]texto impreso
García Martín, Elena Salobrar ; Hoz Montañana, María Rosa de ; Rojas López, María Blanca ; Ramírez Sebastián, Ana Isabel ; Salazar Corral, Juan José ; Yubero Pancorbo, Raquel ; Gil Gregorio, Pedro ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Hindawi Publishing Corporation | 2015-05-20Purpose. To analyze in mild Alzheimer's disease (MAD) patients, GDS-4 (Reisberg Scale), whether or not some psychophysical tests (PTs) support OCT macular findings in the same group of MAD patients reported previously. Methods. Twenty-three MAD [...]texto impreso
Jañez Escalada, Luis ; Jáñez García, Lucía ; García Martín, Elena Salobrar ; Santos Mayo, Alejandro ; Hoz Montañana, María Rosa de ; Yubero Pancorbo, Raquel ; Gil Gregorio, Pedro ; Ramirez Sebastian, Jose Manuel | Nature Publishing Group | 2019The retina is an attractive source of biomarkers since it shares many features with the brain. Thickness differences in 10 retinal layers between 19 patients with mild Alzheimer’s disease (AD) and a control group of 24 volunteers were investigat[...]texto impreso
García Martín, Elena Salobrar ; Ramírez Sebastián, Ana Isabel ; Hoz Montañana, Rosa de ; Rojas, Pilar ; Salazar Corral, Juan José ; Rojas López, Blanca ; Yubero Pancorbo, Raquel ; Gil, Pedro ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Intech | 2016-09-28Over the last few decades, the importance of ophthalmic examination in neurodegenerative diseases of the CNS has reportedly increased. The retina is an extension of the CNS and thus should not be surprising to find abnormal results in both the t[...]
