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Gil Bona, Ana ; Parra Giraldo, Claudia Marcela ; Hernaez, Maria Luisa ; Reales Calderón, José Antonio ; Solis, Norma V. ; Filler, Scott G. ; Monteoliva Díaz, Lucía ; Gil, Concha | Elsevier | 2015-09-08The ability to switch from yeast to hyphal growth is essential for virulence in Candida albicans. The cell surface is the initial point of contact between the fungus and the host. In this work, a free-gel proteomic strategy based on tryptic dige[...]texto impreso
Reales Calderón, José Antonio ; Vaz, Catarina ; Monteoliva Díaz, Lucía ; Molero, Gloria ; Gil, Concha | American Chemical Society | 2016-10-14The effectiveness of macrophages in the response to systemic candidiasis is crucial to an effective clearance of the pathogen. The secretion of proteins, mRNAs, non-coding RNAs and lipids through extracellular vesicles (EVs) is one of the mechan[...]texto impreso
Vialás, Vital ; Sun, Zhi ; Loureiro yPenha, Carla Verónica ; Carrascal, Montserrat ; Abian, J. ; Monteoliva Díaz, Lucía ; Deutsch, Eric W. ; Aebersold, Ruedi ; Moritz, Robert L. ; Gil, Concha | Elsevier | 2014Candida albicans public proteomic datasets, though growing steadily in the last few years, still have a very limited presence in online repositories. We report here the creation of a C. albicans PeptideAtlas comprising near 22,000 distinct pepti[...]texto impreso
Uno de los objetivos fundamentales de nuestro grupo de investigación es la identificación de distintas funciones celulares de la célula fúngica que puedan utilizarse en el desarrollo de nuevos fármacos antifungicos. En este trabajo se ha clonado[...]texto impreso
Buján, Noemí ; Hernández Haro, Carolina ; Monteoliva Díaz, Lucía ; Gil, Concha ; Magariños, Beatriz | Elsevier | 2015-09-08Edwardsiella tarda is an enteric opportunistic pathogen that causes a great loss in aquaculture. This species has been described as a phenotypical homogeneous group; in contrast, serological studies and molecular typing revealed a wide heterogen[...]texto impreso
Rodríguez Peña, José Manuel ; Monteoliva Díaz, Lucía ; Molero Martín-Portugués, María Gloria ; Alonso Monge, Rebeca María del Mar ; García Sanchez, Raul ; Amador García, Ahinara | 2020-06-01En las diferentes clases prácticas relacionadas con asignaturas de Microbiología, como sucede en otras áreas de conocimiento, un aspecto que requiere especial atención es el diseño y la elaboración de herramientas que contribuyan a facilitar y m[...]texto impreso
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Vaz, Catarina Oliveira ; Reales Calderón, José Antonio ; Pitarch, Aida ; Vellosillo, Perceval ; Trevisan Herraz, Marco ; Hernáez Sánchez, Maria Luisa ; Monteoliva Díaz, Lucía ; Gil García, Concha | ACS | 2019-04-15Macrophages are involved in the primary human response to Candida albicans. After pathogen recognition, signaling pathways are activated, leading to the production of cytokines, chemokines, and antimicrobial peptides. ATP binding proteins are cr[...]texto impreso
Gil Bona, Ana ; Monteoliva Díaz, Lucía ; Gil García, Concha | 2015-08-31Candida albicans secretes numerous proteins related to cell wall remodeling, adhesion, nutrient acquisition and host interactions. Also, extracellular vesicles containing cytoplasmic proteins are secreted into the medium. The C. albicans ecm33/e[...]texto impreso
Hernández Haro, Carolina ; Llopis, Silvia ; Molina, María ; Monteoliva Díaz, Lucía ; Gil, Concha | Elsevier | 2015-01-01Saccharomyces cerevisiae is considered a safe microorganism widely used as a dietary supplement. However, in the latest decades several cases of S. cerevisiae infections have been reported. Recent studies in a murine model of systemic infection [...]texto impreso
Monteoliva Díaz, Lucía ; Molero Martín-Portugués, María Gloria ; Rodríguez Peña, José Manuel ; Alonso Monge, Rebeca María del Mar ; García Sanchez, Raul ; Oliveira Vaz, Catarina | 2018-06-30El proyecto se ha desarrollado según lo previsto y se han alcanzado de manera muy satisfactoria los objetivos propuestos, generándose informes virtuales de prácticas de Microbiología Clínica de 4º de Farmacia y un banco de fotografías de pruebas[...]texto impreso
Llopis, Silvia ; Hernández Haro, Carolina ; Monteoliva Díaz, Lucía ; Querol, Amparo ; Molina, María ; Fernández Espinar, María T. | Public Library of Science | 2014-05-30Saccharomyces cerevisiae plays a beneficial role in health because of its intrinsic nutritional value and bio-functional properties, which is why it is also used as a dietary supplement. However, the perception that S. cerevisiae is harmless has[...]texto impreso
Gil Bona, Ana ; Lla Palacios, Arancha ; Parra Giraldo, Claudia Marcela ; Vivando, F. ; Nombela, César ; Monteoliva Díaz, Lucía ; Gil, Concha | ACS | 2015Different signal transduction pathways mediated by MAP kinases have been described in Candida albicans. These pathways sense different stimuli and, therefore, elaborate specific responses. Hog1 was identified as the MAPK that is primarily involv[...]texto impreso
Gil Bona, Ana ; Amador García, Ahinara ; Gil, Concha ; Monteoliva Díaz, Lucía | Elsevier | 2018-05-30The cell surface and secreted proteins are the initial points of contact between Candida albicans and the host. Improvements in protein extraction approaches and mass spectrometers have allowed researchers to obtain a comprehensive knowledge of [...]texto impreso
