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Título:
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A method for predicting protein structure from sequence
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Autores:
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Skolnick, Jeffrey ;
Kolinski, Andrzej ;
Brooks, Charles L. ;
Godzik, Adam ;
Rey, Antonio
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Tipo de documento:
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texto impreso
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Editorial:
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Elsevier, 1993
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Dimensiones:
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application/pdf
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Nota general:
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info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias: Química: Química física
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Tipo = Artículo
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Resumen:
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The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones.
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En línea:
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https://eprints.ucm.es/43831/1/CurrentBiol_Skolnick1993.pdf
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