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Título:
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Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to ?-lactams in Haemophilus influenzae
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Autores:
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Søndergaard, Annette ;
San Millán, Álvaro ;
Santos López, Alfonso ;
Nielsen, Signe M ;
González Zorn, Bruno ;
Nørskov-Lauritsen, Niels
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Tipo de documento:
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texto impreso
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Editorial:
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American Society for Microbiology, 2012-09
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Dimensiones:
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application/pdf
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Nota general:
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info:eu-repo/semantics/restrictedAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Veterinaria
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Tipo = Artículo
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Resumen:
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TEM-1 is the dominant ?-lactamase of Haemophilus influenzae and can be located on small plasmids. Three distinct plasmids with sizes from 4,304 to 5,646 nucleotides (nt) were characterized: pA1606, pA1209, and pPN223. In addition to TEM-1 and a replication enzyme of the Rep 3 superfamily, pA1606 carries a Tn3 resolvase gene and pA1606 and pA1209 carry an open reading frame (ORF) similar to a plasmid recombination enzyme gene described in Gram-positive bacteria. The plasmids transformed strain Rd to the ampicillin-resistant phenotype.
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En línea:
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https://eprints.ucm.es/39668/1/509.pdf
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