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Estradiol, either from peripheral or central origin, activates multiple molecular neuroprotective and neuroreparative responses that, being mediated by estrogen receptors or by estrogen receptor independent mechanisms, are initiated at the membr[...]texto impreso
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Crespo Castrillo, Andrea ; Yanguas Casás, Natalia ; Arévalo, María Ángeles ; Azcoitia Elías, Iñigo ; Barreto, George E. ; García Segura, Luis Miguel | Humana Press | 2018-03-26Previous studies have shown that estradiol reduces reactive gliosis after a stab wound injury in the cerebral cortex. Since the therapeutic use of estradiol is limited by its peripheral hormonal effects, it is of interest to determine whether sy[...]
