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Torres, María ; Palomares, Oscar ; Quiralte, Joaquín ; Pauli, Gabrielle ; Rodríguez García, Rosalía ; Villalba, Mayte | PLOS | 2015-07Endo-?-1,3-glucanases are widespread enzymes with glycosyl hydrolitic activity involved in carbohydrate remodelling during the germination and pollen tube growth. Although members of this protein family with allergenic activity have been reporte[...]texto impreso
Gamo, Ana M. ; Gónzalez-Vera, Juan A. ; Rueda-Zubiaurre, Ainoa ; Alonso, Dulce ; Vázquez-Villa, Henar ; Martín-Couce, Lidia ; Palomares, Oscar ; López, Juan A. ; Martín-Fontecha, Mar ; Benhamú, Bellinda ; López-Rodríguez, María L. ; Ortega-Gutiérrez, Silvia | Wiley | 2015Determination of the targets of a compound remains an essential aspect in drug discovery. A complete understanding of all binding interactions is critical to recognize in advance both therapeutic effects and undesired consequences. However, the[...]texto impreso
Sirvent, Sofía ; Cantó, Belén ; Gómez, Francisca ; Blanca, Natalia ; Cuesta-Herranz, Javier ; Canto, Gabriela ; Blanca, Miguel ; Rodíguez, Rosalía ; Villalba, Mayte ; Palomares, Oscar | John Wiley & Sons Ltd | 2014Background:Act d 12 (11S globulin) and Act d 13 (2S albumin) are two novel relevant allergens from kiwi seeds that might be useful to improve the diagnostic sensitivity and the management of kiwifruit-allergic patients. Objective:To perform a co[...]texto impreso
Hernández Torres, Gloria ; Enríquez Palacios, Ernesto ; Mecha Rodríguez, Miriam ; Feliú Martínez, Ana ; Rueda Zubiaurre, Ainoa ; Angelina Querencias, Alba ; Martín Cruz, Leticia ; Martín Fontecha, María del Mar ; Palomares, Oscar ; Guaza Rodríguez, Carmen ; Peña Cabrera, Eduardo ; López Rodríguez, María L. ; Ortega Gutiérrez, Silvia | American Chemical Society (ACS) | 2018-05-07Serotonin (5-HT) modulates key aspects of the immune system. However, its precise function and the receptors involved in the observed effects have remained elusive. Among the different serotonin receptors, 5-HT1A plays an important role in the i[...]texto impreso
Martín Fontecha, María del Mar ; Angelina Querencias, Alba ; Rückert, Beate ; Rueda Zubiaurre, Ainoa ; Martín Cruz, Leticia ; Veen, Willem van de ; Akdis, Mübeccel ; Ortega Gutiérrez, Silvia ; López Rodríguez, María Luz ; Akdis, Cezmi A. ; Palomares, Oscar | American Chemical Society (ACS) | 2018-02-21The human endogenous cannabinoid system (ECS) regulates key physiological processes and alterations in its signaling pathways, and endocannabinoid levels are associated with diseases such as neurological and neuropsychiatric conditions, cancer, [...]texto impreso
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Sirvent, Sofía ; Cantó, Belén ; Cuesta-Herranz, Javier ; Gómez, Francisca ; Canto, Gabriela ; Blanca, Natalia ; Rodríguez, Rosalía ; Villalba, Mayte ; Palomares, Oscar | Elsevier | 2014Background: Kiwifruit is a common cause of IgE-mediated food allergy. Component-resolved diagnosis of kiwifruit allergy suggests that relevant allergenic components are still undiscovered. The presence of allergens in kiwi seeds has not been inv[...]
