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Tume, L. ; Gallo, Carla ; Malaga-Trillo, E. ; Poletti, Giovanni ; Rojas, R. ; Vaisberg, A. J. | Federation of American Society of Experimental Biology | 2019-01-25T16:20:58ZBackground: Schizophrenia is a severe mental disorder that affects approximately 1% of the population. The main symptom is psychosis in which thought and emotions are impaired. Current pharmacological treatments for schizophrenia are partially e[...]texto impreso
Gu, Wanjun ; Wuren, Tana ; Xu, Ian ; Qin, Ga ; Yan, Ma ; Wei, Guan ; Wagner, Harrieth ; Macarlupu, Jose ; Vicardo, Gustavo ; Anza, Cecilia ; Villafuerte, Francisco ; Ge, Ri-Li ; Wagner, Peter ; Simonson, Tatum | Federation of American Society of Experimental Biology | 2020-07-14T00:01:12ZAn acute increase in hemoglobin concentration ([Hb]) up to 1.6 g/dL has been previously reported under the condition of exercise-induced hypoxemia in sea level individuals with COPD (Schagatay et.al 2015). Changes in [Hb] have been attributed to[...]texto impreso
Richalet, J. P. ; Gazal, S. ; Espinoza, J. R. ; Austerlitz, F. ; Macarlupu, J. L. ; León-Velarde, F. ; Marchant, D. ; Gouya, L. | Federation of American Society of Experimental Biology | 2019-01-25T16:20:59ZChronic mountain sickness (CMS) is a pathological condition resulting from the loss of adaptation to high altitude. The syndrome is characterized by an excessive number of red blood cells (Excessive Erythropoiesis) associated with a high concent[...]texto impreso
Heinrich, Erica C. ; Gaio, Eduardo ; Powell, Frank L. ; Macarlupu, Jose Luis ; Anza-Ramirez, Cecilia ; Corante, Noemi ; Vizcardo-Galindo, Gustavo ; Villafuerte, Francisco C. ; Simonson, Tatum S. | Federation of American Society of Experimental Biology | 2019-02-22T14:54:31ZMultiple adaptive phenotypes for high-altitude and hypoxic stress have developed by distinct evolutionary trajectories in highland populations. For example, considerable variation is observed in the hypoxic ventilatory response (HVR) of Tibetans[...]texto impreso
Zhao, Huiwen ; Perkins, Guy ; Callacondo, David ; Appenzeller, Otto ; Haddad, Gabriel | Federation of American Society of Experimental Biology | 2019-02-22T14:55:30ZChronic mountain sickness (CMS) is a disease that potentially threatens a large segment of the high altitude population (more than 140 million highlanders) during extended living over 2500m. Patients with CMS suffer from severe hypoxemia, erythr[...]texto impreso
Azad, Priti ; Patel, Gargi ; Bermutez, Daniella ; Villafuerte, Francisco ; Haddad, Gabriel | Federation of American Society of Experimental Biology | 2020-07-14T00:00:56ZRationale Chronic mountain sickness (CMS), or Monge's disease, is an advancing and debilitating syndrome caused by chronic (years) exposure to high altitude hypoxia, as experienced by people living in the Andean region. Excessive erythrocytosis [...]texto impreso
Macarlupu, Jose L. ; Vizcardo-Galindo, Gustavo ; Figueroa-Mujíca, Rómulo ; Villafuerte, Francisco C. | Federation of American Society of Experimental Biology | 2020-07-14T00:02:32ZExcessive erythrocytosis (EE; Hct ? 63% in men) is the hallmark of Monge?s disease or Chronic Mountain Sickness (CMS), a debilitating syndrome with high prevalence in Andean highlanders. EE is associated with typical CMS neurological symptoms an[...]texto impreso
Heinicke, Katja ; Heinicke, Ilmar ; Jelkmann, Wolfgang ; Rawlings, Pablo ; Behn, Claus ; Gassmann, Max | Federation of American Society of Experimental Biology | 2019-02-22T14:54:31ZThe objective of this study was to investigate if prolonged training at moderate altitude leads to complete acclimatization of maximal oxygen uptake (VO2max), and if physical activity at this altitude promotes additional skeletal muscle adaption[...]
